Solid-phase synthesis of pyrido[2,3-d]pyrimidin-7-ones

Tetrahedron Letters

Volumn 46, Issue 50, 2005, Pages 8749-8752

  Angiolini, Mauro ^a   Bassini, Domenico Fusar ^a   Gude, Markus ^a,b   Menichincheri, Maria ^a  

^a Discovery Research Oncology   (Italy)

^b ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

Formyl resin; Library; Pyrido 2,3 d pyrimidin 7 one; Scaffold; Solid phase

Indexed keywords

AMINE; MESYLIC ACID DERIVATIVE; POLYMER; PYRIDO[2,3 D]PYRIMIDIN 7 ONE; PYRIMIDINE DERIVATIVE; RESIN; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; DRUG SYNTHESIS; OXIDATION; SOLID; SOLID PHASE SYNTHESIS;

EID: 27744511792     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.10.030     Document Type: Article

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9. 6): δ 9.18 (t, 1H), 8.34 (d, 2H), 8.03 (m, 3H), 7.47 (m, 7H), 6.62 (t, 1H), 6.36 (d, 1H), 4.51 (d, 2H), 3.62 (m, 4H), 3.33 (m, 4H), 2.58 (s, 3H); LC/MS (ESI): m/z 647 (M+H).