Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure

Infection, Genetics and Evolution

Volumn 9, Issue 1, 2009, Pages 62-70

  Dumans, Ana T ^a   Barreto, Cláudia C ^b   Santos, André F ^c   Arruda, Mônica ^c   Sousa, Thatiana M ^c   Machado, Elizabeth S ^c   Sabino, Ester C ^d   Brindeiro, Rodrigo M ^c   Tanuri, Amílcar ^c   Duarte, Alberto J ^b   Soares, Marcelo A ^c,e  

^a FEDERAL UNIVERSITY OF THE STATE OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d FUNDAÇÃO PRÓ SANGUE HEMOCENTRO DE SÃO PAULO   (Brazil)

^e INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Brazil; Drug resistance mutations; HIV 1; Pediatric infection; Protease; Subtype B; Subtype F1

Indexed keywords

AMPRENAVIR; INDINAVIR; LOPINAVIR; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR;

ADULT; AMINO ACID SEQUENCE; ANTIVIRAL RESISTANCE; ARTICLE; BRAZIL; CHILD; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EXPOSURE; DRUG TREATMENT FAILURE; FEMALE; GENETIC POLYMORPHISM; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; UNINDEXED SEQUENCE; VIRUS LOAD; VIRUS MUTATION; VIRUS STRAIN;

ADULT; ANTI-HIV AGENTS; BRAZIL; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, GENETIC; STATISTICS, NONPARAMETRIC; VIRAL LOAD;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 57649126297     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2008.10.002     Document Type: Article

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