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Volumn 34, Issue 1, 2009, Pages 248-249

Promise of mGluR2/3 activators in psychiatry

Author keywords

[No Author keywords available]

Indexed keywords

BIPHENYLINDANONE A; EGLUMETAD; LY 487379; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 2 AGONIST; METABOTROPIC RECEPTOR 2 POSITIVE ALLOSTERIC MODULATOR; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 3 AGONIST; METABOTROPIC RECEPTOR AGONIST; PSYCHEDELIC AGENT; UNCLASSIFIED DRUG;

EID: 57649112566     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2008.156     Document Type: Short Survey
Times cited : (33)

References (6)
  • 1
    • 27744597869 scopus 로고    scopus 로고
    • A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity
    • Galici R, Echemendia NG, Rodriguez AL, Conn PJ (2005). A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity. J Pharmacol Exp Ther 315: 1181-1187.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1181-1187
    • Galici, R.1    Echemendia, N.G.2    Rodriguez, A.L.3    Conn, P.J.4
  • 2
    • 33745227414 scopus 로고    scopus 로고
    • Biphenylindanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice
    • Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC et al (2006). Biphenylindanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol Exp Ther 318: 173-185.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 173-185
    • Galici, R.1    Jones, C.K.2    Hemstapat, K.3    Nong, Y.4    Echemendia, N.G.5    Williams, L.C.6
  • 3
    • 0038155299 scopus 로고    scopus 로고
    • Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: Synthesis and subtype selectivity of N-(4-(2- methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl) pyrid-3-ylmethylamine
    • Johnson MP, Baez M, Jagdmann Jr GE, Britton TC, Large TH, Callagaro DO et al (2003). Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2- methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl) pyrid-3-ylmethylamine. J Med Chem 46: 3189-3192.
    • (2003) J Med Chem , vol.46 , pp. 3189-3192
    • Johnson, M.P.1    Baez, M.2    Jagdmann Jr, G.E.3    Britton, T.C.4    Large, T.H.5    Callagaro, D.O.6
  • 4
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, Andreev BV et al (2007). Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 13: 1102-1107.
    • (2007) Nat Med , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3    Lowe, S.L.4    Jackson, K.A.5    Andreev, B.V.6
  • 5
    • 0011900802 scopus 로고    scopus 로고
    • Preclinical pharmacology of mGlu2/3 receptor agonists: Novel agents for schizophrenia?
    • Schoepp DD, Marek GJ (2002). Preclinical pharmacology of mGlu2/3 receptor agonists: novel agents for schizophrenia? Curr Drug Target CNS Neurol Disord 1: 215-225.
    • (2002) Curr Drug Target CNS Neurol Disord , vol.1 , pp. 215-225
    • Schoepp, D.D.1    Marek, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.