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Volumn 63, Issue 1, 2009, Pages 121-127

Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients

Author keywords

Ethnicity; Gemcitabine; Gene variants; Non small cell lung cancer; Polymorphism

Indexed keywords

CARBOPLATIN; DNA; GEMCITABINE;

EID: 57649112390     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2008.04.010     Document Type: Article
Times cited : (63)

References (32)
  • 2
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics-drug disposition, drug targets, and side effects
    • Evans W.E., and McLeod H.L. Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med 348 (2003) 538-549
    • (2003) N Engl J Med , vol.348 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 4
    • 0344197480 scopus 로고    scopus 로고
    • Cancer pharmacogenetics: polymorphisms, pathways and beyond
    • Ulrich C.M., Robien K., and McLeod H.L. Cancer pharmacogenetics: polymorphisms, pathways and beyond. Nat Rev Cancer 3 (2003) 912-920
    • (2003) Nat Rev Cancer , vol.3 , pp. 912-920
    • Ulrich, C.M.1    Robien, K.2    McLeod, H.L.3
  • 5
    • 33644550908 scopus 로고    scopus 로고
    • Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population
    • Lee S.C., Ng S.S., Oldenburg J., Chong P.Y., Rost S., Guo J.Y., et al. Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population. Clin Pharmacol Ther 79 (2006) 197-205
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 197-205
    • Lee, S.C.1    Ng, S.S.2    Oldenburg, J.3    Chong, P.Y.4    Rost, S.5    Guo, J.Y.6
  • 6
    • 28444436251 scopus 로고    scopus 로고
    • Advances and challenges in fluoropyrimidine pharmacogenomics and pharmacogenetics
    • Soong R., and Diasio R.B. Advances and challenges in fluoropyrimidine pharmacogenomics and pharmacogenetics. Pharmacogenomics 6 (2005) 835-847
    • (2005) Pharmacogenomics , vol.6 , pp. 835-847
    • Soong, R.1    Diasio, R.B.2
  • 7
    • 1442302331 scopus 로고    scopus 로고
    • Mammalian nucleoside transporters
    • Kong W., Engel K., and Wang J. Mammalian nucleoside transporters. Curr Drug Metab 5 (2004) 63-84
    • (2004) Curr Drug Metab , vol.5 , pp. 63-84
    • Kong, W.1    Engel, K.2    Wang, J.3
  • 8
    • 0033520708 scopus 로고    scopus 로고
    • Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters
    • Mackey J.R., Yao S.Y., Smith K.M., Karpinski E., Baldwin S.A., Cass C.E., et al. Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. J Natl Cancer Inst 91 (1999) 1876-1881
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1876-1881
    • Mackey, J.R.1    Yao, S.Y.2    Smith, K.M.3    Karpinski, E.4    Baldwin, S.A.5    Cass, C.E.6
  • 9
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-beta-d-arabinofuranosylcytosine
    • Heinemann V., Hertel L.W., Grindey G.B., and Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-beta-d-arabinofuranosylcytosine. Cancer Res 48 (1988) 4024-4031
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 10
    • 0029584109 scopus 로고
    • Preclinical characteristics of gemcitabine
    • Plunkett W., Huang P., and Gandhi V. Preclinical characteristics of gemcitabine. Anticancer Drugs 6 Suppl. 6 (1995) 7-13
    • (1995) Anticancer Drugs , vol.6 , Issue.SUPPL. 6 , pp. 7-13
    • Plunkett, W.1    Huang, P.2    Gandhi, V.3
  • 11
    • 0025049372 scopus 로고
    • Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine
    • Heinemann V., Xu Y.Z., Chubb S., Sen A., Hertel L.W., Grindey G.B., et al. Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine. Mol Pharmacol 38 (1990) 567-572
    • (1990) Mol Pharmacol , vol.38 , pp. 567-572
    • Heinemann, V.1    Xu, Y.Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6
  • 12
    • 0026571795 scopus 로고
    • Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: a mechanism of self-potentiation
    • Heinemann V., Xu Y.Z., Chubb S., Sen A., Hertel L.W., Grindey G.B., et al. Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: a mechanism of self-potentiation. Cancer Res 52 (1992) 533-539
    • (1992) Cancer Res , vol.52 , pp. 533-539
    • Heinemann, V.1    Xu, Y.Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6
  • 13
    • 0031808788 scopus 로고    scopus 로고
    • Cross-resistance of the gemcitabine resistant human ovarian cancer cell line AG6000 to standard and investigational drugs
    • Bergman A.M., Pinedo H.M., Ruiz van Haperen V.W., Veerman G., Kuiper C.M., and Peters G.J. Cross-resistance of the gemcitabine resistant human ovarian cancer cell line AG6000 to standard and investigational drugs. Adv Exp Med Biol 431 (1998) 587-590
    • (1998) Adv Exp Med Biol , vol.431 , pp. 587-590
    • Bergman, A.M.1    Pinedo, H.M.2    Ruiz van Haperen, V.W.3    Veerman, G.4    Kuiper, C.M.5    Peters, G.J.6
  • 14
    • 5044242910 scopus 로고    scopus 로고
    • Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway
    • Fukunaga A.K., Marsh S., Murry D.J., Hurley T.D., and McLeod H.L. Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway. Pharmacogenomics J 4 (2004) 307-314
    • (2004) Pharmacogenomics J , vol.4 , pp. 307-314
    • Fukunaga, A.K.1    Marsh, S.2    Murry, D.J.3    Hurley, T.D.4    McLeod, H.L.5
  • 15
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P., Arbuck S.G., Eisenhauer E.A., Wanders J., Kaplan R.S., Rubinstein L., et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92 (2000) 205-216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 16
    • 19944429421 scopus 로고    scopus 로고
    • Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance
    • Bepler G., Zheng Z., Gautam A., Sharma S., Cantor A., Sharma A., et al. Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance. Lung Cancer 47 (2005) 183-192
    • (2005) Lung Cancer , vol.47 , pp. 183-192
    • Bepler, G.1    Zheng, Z.2    Gautam, A.3    Sharma, S.4    Cantor, A.5    Sharma, A.6
  • 17
    • 10744229920 scopus 로고    scopus 로고
    • Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations
    • Gray J.H., Mangravite L.M., Owen R.P., Urban T.J., Chan W., Carlson E.J., et al. Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations. Mol Pharmacol 65 (2004) 512-519
    • (2004) Mol Pharmacol , vol.65 , pp. 512-519
    • Gray, J.H.1    Mangravite, L.M.2    Owen, R.P.3    Urban, T.J.4    Chan, W.5    Carlson, E.J.6
  • 18
    • 0141507954 scopus 로고    scopus 로고
    • Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene
    • Kawakami K., and Watanabe G. Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene. Cancer Res 63 (2003) 6004-6007
    • (2003) Cancer Res , vol.63 , pp. 6004-6007
    • Kawakami, K.1    Watanabe, G.2
  • 19
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 (2005) 263-265
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 20
    • 33645298447 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients
    • de las Penas R., Sanchez-Ronco M., Alberola V., Taron M., Camps C., Garcia-Carbonero R., et al. Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients. Ann Oncol 17 (2006) 668-675
    • (2006) Ann Oncol , vol.17 , pp. 668-675
    • de las Penas, R.1    Sanchez-Ronco, M.2    Alberola, V.3    Taron, M.4    Camps, C.5    Garcia-Carbonero, R.6
  • 21
    • 33749036570 scopus 로고    scopus 로고
    • DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy
    • Quintela-Fandino M., Hitt R., Medina P.P., Gamarra S., Manso L., Cortes-Funes H., et al. DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy. J Clin Oncol 24 (2006) 4333-4339
    • (2006) J Clin Oncol , vol.24 , pp. 4333-4339
    • Quintela-Fandino, M.1    Hitt, R.2    Medina, P.P.3    Gamarra, S.4    Manso, L.5    Cortes-Funes, H.6
  • 22
    • 33748324572 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in DNA repair genes might be prognostic factors in muscle-invasive bladder cancer patients treated with chemoradiotherapy
    • Sakano S., Wada T., Matsumoto H., Sugiyama S., Inoue R., Eguchi S., et al. Single nucleotide polymorphisms in DNA repair genes might be prognostic factors in muscle-invasive bladder cancer patients treated with chemoradiotherapy. Br J Cancer 95 (2006) 561-570
    • (2006) Br J Cancer , vol.95 , pp. 561-570
    • Sakano, S.1    Wada, T.2    Matsumoto, H.3    Sugiyama, S.4    Inoue, R.5    Eguchi, S.6
  • 23
    • 3843130823 scopus 로고    scopus 로고
    • A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer
    • Stoehlmacher J., Park D.J., Zhang W., Yang D., Groshen S., Zahedy S., et al. A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer. Br J Cancer 91 (2004) 344-354
    • (2004) Br J Cancer , vol.91 , pp. 344-354
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3    Yang, D.4    Groshen, S.5    Zahedy, S.6
  • 24
    • 33745254202 scopus 로고    scopus 로고
    • Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab
    • Zhang W., Gordon M., Press O.A., Rhodes K., Vallbohmer D., Yang D.Y., et al. Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab. Pharmacogenet Genom 16 (2006) 475-483
    • (2006) Pharmacogenet Genom , vol.16 , pp. 475-483
    • Zhang, W.1    Gordon, M.2    Press, O.A.3    Rhodes, K.4    Vallbohmer, D.5    Yang, D.Y.6
  • 25
    • 20244367613 scopus 로고    scopus 로고
    • Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2
    • Owen R.P., Gray J.H., Taylor T.R., Carlson E.J., Huang C.C., Kawamoto M., et al. Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2. Pharmacogenet Genomics 15 (2005) 83-90
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 83-90
    • Owen, R.P.1    Gray, J.H.2    Taylor, T.R.3    Carlson, E.J.4    Huang, C.C.5    Kawamoto, M.6
  • 26
    • 34447303456 scopus 로고    scopus 로고
    • Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism
    • Sugiyama E., Kaniwa N., Kim S.R., Kikura-Hanajiri R., Hasegawa R., Maekawa K., et al. Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. J Clin Oncol 25 (2007) 32-42
    • (2007) J Clin Oncol , vol.25 , pp. 32-42
    • Sugiyama, E.1    Kaniwa, N.2    Kim, S.R.3    Kikura-Hanajiri, R.4    Hasegawa, R.5    Maekawa, K.6
  • 27
    • 20244364241 scopus 로고    scopus 로고
    • Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin
    • Yonemori K., Ueno H., Okusaka T., Yamamoto N., Ikeda M., Saijo N., et al. Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin. Clin Cancer Res 11 (2005) 2620-2624
    • (2005) Clin Cancer Res , vol.11 , pp. 2620-2624
    • Yonemori, K.1    Ueno, H.2    Okusaka, T.3    Yamamoto, N.4    Ikeda, M.5    Saijo, N.6
  • 28
    • 0025758615 scopus 로고
    • Ethnic differences in drug disposition and responsiveness
    • Wood A.J., and Zhou H.H. Ethnic differences in drug disposition and responsiveness. Clin Pharmacokinet 20 (1991) 350-373
    • (1991) Clin Pharmacokinet , vol.20 , pp. 350-373
    • Wood, A.J.1    Zhou, H.H.2
  • 31
    • 16644398719 scopus 로고    scopus 로고
    • Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group
    • Rudd R.M., Gower N.H., Spiro S.G., Eisen T.G., Harper P.G., Littler J.A., et al. Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group. J Clin Oncol 23 (2005) 142-153
    • (2005) J Clin Oncol , vol.23 , pp. 142-153
    • Rudd, R.M.1    Gower, N.H.2    Spiro, S.G.3    Eisen, T.G.4    Harper, P.G.5    Littler, J.A.6
  • 32
    • 33644684204 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: the Swedish Lung Cancer Study Group
    • Sederholm C., Hillerdal G., Lamberg K., Kolbeck K., Dufmats M., Westberg R., et al. Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: the Swedish Lung Cancer Study Group. J Clin Oncol 23 (2005) 8380-8388
    • (2005) J Clin Oncol , vol.23 , pp. 8380-8388
    • Sederholm, C.1    Hillerdal, G.2    Lamberg, K.3    Kolbeck, K.4    Dufmats, M.5    Westberg, R.6


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