Biological monitoring and questionnaire for assessing exposure to ethylenebisdithiocarbamates in a multicenter European field study

Human and Experimental Toxicology

Volumn 27, Issue 9, 2008, Pages 681-691

  Fustinoni, S ^a,h   Campo, L ^a   Liesivuori, J ^b,c   Pennanen, S ^b   Vergieva, T ^d   Van Amelsvoort, L G P M ^e   Bosetti, C ^f   Van Loveren, H ^e,g   Colosio, C ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d National Center of Public Health Protection Bulgaria   (Bulgaria)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^g NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^h S Paolo Hospital Unit ^*  (Italy)

Author keywords

Biological monitoring; Ethylenebisdithiocarbamates; Exposure assessment; Questionnaire; Urinary ethylenethiourea

Indexed keywords

2 IMIDAZOLIDINETHIONE; ABAMECTIM; ALDICARB; CHLOOR; COPPER; CREATININE; DIMETHOMORPH; FLUAZINAM; GOLTIX; HEXACONAZOLE; IPRODIONE; MANCOZEB; MANEB; METHOMYL; METYRAM; PARAQUAT; PENCONAZOLE; PESTICIDE; PROPAMOCARB; QUINOXIFEN; SUMIDEN; THIAMETAXAM; UNCLASSIFIED DRUG; ZINEB;

ADULT; AGRICULTURAL WORKER; ARTICLE; BIOLOGICAL MONITORING; BULGARIA; CLEANING; CONTROLLED STUDY; CREATININE URINE LEVEL; DRUG URINE LEVEL; FEMALE; FIELD STUDY; FLORICULTURE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OCCUPATIONAL EXPOSURE; POTATO; PRIORITY JOURNAL; PROTECTIVE EQUIPMENT; QUALITY CONTROL; QUESTIONNAIRE; SEASONAL VARIATION; URINALYSIS; VINEYARD; WORK ENVIRONMENT; WORKING TIME;

ADULT; AGRICULTURE; BULGARIA; CREATINE; ENVIRONMENTAL MONITORING; ETHYLENEBIS(DITHIOCARBAMATES); ETHYLENETHIOUREA; FEMALE; FINLAND; HUMANS; ITALY; MALE; MIDDLE AGED; NETHERLANDS; OCCUPATIONAL EXPOSURE; OCCUPATIONS; QUESTIONNAIRES; RISK ASSESSMENT; TIME FACTORS;

SOLANUM TUBEROSUM;

EID: 57449119917     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327108100003     Document Type: Article

References (27)

1. Baldi I. Lebailly P. Jean S. Rougetet L. Dulaurent S. Marquet P.. Pesticide contamination of workers in vineyards in France. J Expo Sci Environ Epidemiol 2006 ; 16: 115-124.
2. Arbuckle TE. Burnet R. Cole D. Teschke K. Dosemeci M. Bancej C.. Predictors of Herbicide exposure in farm applicators. Int Arch Occup Environ Health 2002 ; 75: 406-414.
3. Aprea C. Sciarra G. Sartorelli P.. Environmental and biological monitoring of exposure to mancozeb, ethylenethiourea, and dimethoate during industrial formulation. J Toxicol Environ Health A 1998 ; 53: 263-281.
4. Barr DB. Bravo R. Weerasekera G. Caltabiano LM. Whitehead RD. Olsson AO.. Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population. Environ Health Perspect 2004 ; 112: 186-200.
5. Aprea C. Betta A. Catenacci G. Colli A. Lotti A. Minoia C.. Urinary excretion of ethylenethiourea in five volunteers on a controlled diet (multicentric study). Sci Total Environ 1997 ; 203: 167-179.
6. Colosio C. Visentin S. Birindelli S. Campo L. Fustinoni S. Mariani F.. Reference values for ethylenethiourea in urine in Northern Italy: results of a pilot study. Toxicol Lett 2006 ; 162: 153-157.
7. Aprea C. Tumino R. Saieva C. Masala G. Salvini S. Frasca G.. Twenty-four-hour urinary excretion of ten pesticide metabolites in healthy adults in two different areas of Italy (Florence and Ragusa). Sci Total Environ 2004 ; 332: 71-80.
8. Corsini E. Swaen G. Liesivori J. Vergieva T. Van Loveren H. Colosio C.. Effects of pesticide exposure on the human immune system. Hum Exp Toxicol 2008 ; 27: 671-680.
9. Commission of the European Communities. Council Directive 9μ14/EEC. Official Journal of the European Communities L 230 19.8.1991 page 1. Luxembourg, Office for Official Publications of the European Communities; 1991.
10. http://www.osha.gov/dts/chemicalsampling/data/CH_250190.html
11. http://www.cdc.gov/niosh/npg/npgd0379.html
12. American Conference of Governmental Industrial Hygienists. Threshold limit value for chemical substances and physical agents and biological exposure indices. Cincinnati, Ohio: ACGIH; 2004.
13. 16 Deutsche Forschungsgemeinschaft. List of MAK and BAT values 2005. Commission for the investigation of health hazards of chemical compounds in the work area, report no. 41. Weinheim: WILEY-VCH ; 2005.
14. Aprea C. Betta A. Catenacci G. Lotti A. Minoia C. Passini W.. Reference values of urinary ethylenethiourea in four regions of Italy (multicentric study). Sci Total Environ 1996 ; 192: 83-93.
15. Colosio C. Fustinoni S. Birindelli S. Bonomi I. De Paschale G. Mammone T.. Ethylenethiourea in urine as an indicator of exposure to mancozeb in vineyard workers. Toxicol Lett 2002 ; 134: 133-140.
16. Panganiban L. Cortes-Maramba N. Dioquino C. Suplido ML. Ho H. Francisco-Rivera A.. Correlation between blood ethylenethiourea and thyroid gland disorder among banana plantation workers in the Philippines. Environ Health Perspect 2004 ; 112: 42-45.
17. Colosio C. Harari R. Birindelli S. Campo L. Fustinoni S. Harari H.. Esposizione professionale a fungicidi in floricoltori dell'Ecuador. G Ital Med Lav Ergon 2003 ; 25: 107-108 [article in Italian].
18. Colosio C. Fustinoni S. Corsini E. Bosetti C. Birindelli S. Boers D.. Changes in serum markers indicative of health effects in vineyard workers following exposure to the fungicide mancozeb: an Italian study. Biomarkers 2007 ; 12: 574-588.
19. Sottani C. Bettinelli M. Fiorentino ML. Minoia C.. Analytical method for the quantitative determination of urinary ethylenethiourea by liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 2003 ; 17: 2253-2259.
20. 23 Fustinoni S. Campo L. Harari R. Valla C. Foà V. Colosio C.. Kinetic of urinary ethylenethiourea in humans: a field study in agriculture workers. "28th International Congress on Occupational Health (ICOH)", Milan, Italy: Book of abstracts; 2006. p. 143.
21. Fustinoni S. Campo L. Colosio C. Birindelli S. Foà V.. Application of gas chromatographic/mass spectrometry for the determination of urinary ethylenethiourea in humans. J Chromatogr B 2005 ; 814: 251-258.
22. Kurttio P. Savolainen K.. Ethylenethiurea in air and in urine as an indicator of exposure to ethylenebisdithiocarbamate fungicides. Scand J Work Environ Health 1990 ; 16: 203-207.
23. 26 Fustinoni S. Campo L. Birindelli S. Colosio C.. Urinary ethylenethiourea as a biomarker of exposure to ethylenebisdithiocarbamates. In: Martínez Vidal, JL, Garrido Frenich, A, (eds), Methods in biotechnology, vol. 19, in pesticide protocols. Totowa, NJ: Human Press Inc.; 2005. p. 79-89.
24. 27 World Health Organization. Biological monitoring of chemical exposure in the workplace, vol. 1. Geneva: WHO ; 1996.
25. Mutti A.. Biological monitoring in occupational and environmental toxicology. Toxicol Lett 1999 ; 108: 77-89.
26. Kurttio P. Vartiainen T. Savolainen K.. Environmental and biological monitoring of exposure to ethylenebisdiocarbammate fungicides and ethylenethiourea. Br J Ind Med 1990 ; 47: 203-206.
27. http://www.pesticides.gov.uk/publications.asp?id=36