Predictors of herbicide exposure in farm applicators

International Archives of Occupational and Environmental Health

Volumn 75, Issue 6, 2002, Pages 406-414

  Arbuckle, Tye E ^a   Burnett, Rick ^b   Cole, Donald ^c   Teschke, Kay ^d   Dosemeci, Mustafa ^e   Bancej, Christina ^a   Zhang, Jun ^a  

^a HEALTH CANADA   (Canada)

^b Health Canada   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bio monitoring; Environmental exposure; Exposure misclassification; Herbicides; Predictive modelling

Indexed keywords

2 (4 CHLORO 2 METHYLPHENOXY)ACETIC ACID; 2,4 DICHLOROPHENOXYACETIC ACID; HERBICIDE; PESTICIDE;

AGRICULTURAL WORKER; ARTICLE; BIOLOGICAL MONITORING; CANADA; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION COEFFICIENT; EPIDEMIOLOGICAL DATA; HERBICIDE TOLERANCE; HUMAN; OCCUPATIONAL EXPOSURE; PESTICIDE SPRAYING; PREDICTION; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; RETROSPECTIVE STUDY; SELF REPORT; SENSITIVITY AND SPECIFICITY; URINALYSIS; URINE LEVEL; VALIDATION PROCESS; VOLUNTEER;

2,4-DICHLOROPHENOXYACETIC ACID; 2-METHYL-4-CHLOROPHENOXYACETIC ACID; ADULT; AGRICULTURE; BIOLOGICAL MARKERS; COHORT STUDIES; ENVIRONMENTAL MONITORING; FEMALE; HERBICIDES; HUMANS; MALE; MULTIVARIATE ANALYSIS; OCCUPATIONAL EXPOSURE; ONTARIO; PESTICIDES; QUESTIONNAIRES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SELF DISCLOSURE; SENSITIVITY AND SPECIFICITY;

EID: 0036705628     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-002-0323-7     Document Type: Article

References (28)

1. Arbuckle TE, Savitz DA, Mery LS, Curtis KM (1999a) Exposure to phenoxy herbicides and the risk of spontaneous abortion. Epidemiology 10:1-9
2. Arbuckle TE, Schrader SM, Cole D, Hall JC, Bancej CM, Turner LA, Claman P (1999b) 2,4-Dichlorophenoxyacetic acid residues in semen of Ontario farmers. Reprod Toxicol 13:421-429
3. Archibald BA, Solomon KR, Stephenson GR (1994) A new procedure for calibrating the video imaging technique for assessing dermal exposure to pesticides. Arch Environ Contam Toxicol 26:398-402
4. Archibald BA, Solomon KR, Stephenson GR (1995) Estimation of pesticide exposure to greenhouse applicators using video imaging and other assessment techniques. Am Ind Hyg Assoc J 56:226-235
5. Arnold EK, Beasley VR (1989) The pharmacokinetics of chlorinated phenoxy acid herbicides: A literature review. Vet Hum Toxicol 31:121-125
6. Baugher DG (1994) Validation of a pharmacokinetic model to predict exposure to ground boom mixer-loader-applicators to chlorophenoxyacetic acid herbicides. In: Saleh MA, Blancato JN, Nauman CH (eds) Biomarkers of Human Exposure to Pesticides. ACS Symposium Series 542. American Chemical Society, Washington DC, pp 214-230
7. Curtis KM, Savitz DA, Weinberg CR, Arbuckle TE (1999) The effect of pesticide exposure on time to pregnancy. Epidemiology 10:112-117
8. Feldmann RJ, Maibach HI (1974) Percutaneous penetration of some pesticides and herbicides in man. Toxicol Appl Pharmacol 28:126-132
9. Fenske RA, Birnbaum SG (1997) Second generation video imaging technique for assessing dermal exposure (VITAE System). Am Ind Hyg Assoc J 58:636-645
10. Fenske RA, Leffingwell JT, Spear RC (1986a) A video imaging technique for assessing dermal exposure. 1. Instrument design and testing. Am Ind Hyg Assoc J 47:764-770
11. Fenske RA, Wong SM, Leffingwell JT, Spear RC (1986b) A video imaging technique for assessing dermal exposure. II. Fluorescent tracer testing. Am Ind Hyg Assoc J 47:771-775
12. Frank R, Campbell RA, Sirons GJ (1985) Forestry workers involved in aerial application of 2,4-dichlorophenoxyacetic acid (2,4-D): Exposure and urinary excretion. Arch Environ Contam Toxicol 14:427-435
13. Garrod ANI, Phillips AM, Pemberton JA (2001) Potential exposure of hands inside protective gloves - A summary of data from non-agricultural pesticide surveys. Ann Occup Hyg 45:55-60
14. Greenland S (1998) Basic methods for sensitivity analysis and external adjustment. In: Rothman KJ, Greenland S (eds) Modern Epidemiology, 2nd edn. Lippincott-Raven, Philadelphia, pp 343-357
15. Harris SA (1999) The development and validation of a pesticide dose prediction model. PhD dissertation, University of Toronto
16. Harris SA, Solomon KR (1992) Percutaneous penetration of 2,4-dichlorophonoxyacetic acid and 2,4-D dimethylamine salt in human volunteers. J Toxicol Environ Health 36:233-240
17. Harris SA, Solomon KR, Stephenson GR (1992) Exposure of homeowners and bystanders to 2,4-dichlorophenoxyacetic acid (2,4-D). J Environ Sci Health B27:23-38
18. Harris SA, Purdham JT, Corey PN, Sass-Kortsak AM (2000) An evaluation of 24-hour urinary creatinine excretion for use in identification of incomplete urine collections and adjustment of absorbed dose of pesticides. Am Ind Hyg Assoc J 61:649-657
19. Hines CJ, Deddens JA, Tucker SP, Hornung RW (2001) Distributions and determinants of pre-emergent herbicide exposures among custom applicators. Ann Occup Hyg 45:227-239
20. Hoar SK, Blair A, Holmes FF, Boysen CD, Robel RJ, Hoover R, Fraumeni JF (1986) Agricultural herbicide use and risk of lymphoma and soft-tissue sarcoma. JAMA 256:1141-1147
21. Kohli JD, Khanna RN, Gupta BN, Dhar MM, Tandon JS, Sircar KP (1974) Absorption and excretion of 2,4-dichlorophenoxyacetic acid in man. Xenobiotica 4:97-100
22. Kolmodin-Hedman B, Höglund S, Åkerblom M (1983) Studies on phenoxy acid herbicides. I. Field study - Occupational exposure to phenoxy acid herbicides (MCPA, dichlorprop, mecoprop and 2,4-D) in agriculture. Arch Toxicol 54:257-265
23. Libich S, To JC, Frank R, Sirons GJ (1984) Occupational exposure of herbicide applicators to herbicides used along electric power transmission line right-of-way. Am Ind Hyg Assoc J 45:56-62
24. Maibach H, Feldman R, Milby T, Serat W (1971) Regional variation in percutaneous penetration in man. Arch Environ Health 23:208-211
25. Moody RP, Wester RC, Melendres JL, Maibach HI (1992) Dermal absorption of the phenoxy herbicide 2,4-D dimethylamine in humans: Effect of DEET and anatomic site. J Toxicol Environ Health 36:241-250
26. Sauerhoff MW, Braun WH, Blau GE, Gehring PJ (1977) The fate of 2,4-dichlorophenoxyacetic acid (2,4-D) following oral administration to man. Toxicology 8:3-11
27. Savitz DA, Arbuckle T, Kaczor D, Curtis KM (1997) Male pesticide exposure and pregnancy outcome. Am J Epidemiol 146:1025-1036
28. Zahm SH, Weisenburger DD, Babbitt PP, Saal RC, Vaught JB, Cantor KP, Blair A (1990) A case-control study of non-Hodgkin's lymphoma and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in Eastern Nebraska. Epidemiology 1:349-356