Improved thermostability and acetic acid tolerance of Escherichia coli via directed evolution of homoserine o-succinyltransferase

Applied and Environmental Microbiology

Volumn 74, Issue 24, 2008, Pages 7660-7668

  Mordukhova, Elena A ^a   Lee, Hee Soon ^b   Pan, Jae Gu ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Research Institute of Ships and Ocean Engineering   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; AGGLOMERATION; AMINATION; AMINES; AMINO ACIDS; BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CLONING; ENZYMES; GROWTH (MATERIALS); KNOWLEDGE BASED SYSTEMS; ORGANIC ACIDS; PH; PH EFFECTS; STRAIN;

ACCELERATED GROWTHS; ACETIC ACID TREATMENTS; AMINO ACID RESIDUES; AMINO ACID SUBSTITUTIONS; ASPARTIC ACIDS; BIO PROCESSES; DIRECTED EVOLUTIONS; E. COLI; ELEVATED TEMPERATURES; HIGHER TEMPERATURES; HOMOSERINE; HOST STRAINS; IN-VIVO; META GENES; METHIONINE BIOSYNTHESES; RANDOM MUTAGENESISES; TEMPERATURE RANGES;

ESCHERICHIA COLI;

ACETIC ACID; HOMOSERINE SUCCINYLTRANSFERASE;

ACETIC ACID; AMINO ACID; CHROMOSOME; COLIFORM BACTERIUM; ENZYME ACTIVITY; GROWTH RATE; HIGH TEMPERATURE; MUTATION; TOLERANCE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM MUTANT; ESCHERICHIA COLI; MOLECULAR CLONING; NONHUMAN; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY;

ACETIC ACID; AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACILLACEAE; BIOSYNTHETIC PATHWAYS; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DRUG TOLERANCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HEAT-SHOCK RESPONSE; HOMOSERINE O-SUCCINYLTRANSFERASE; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE;

ESCHERICHIA COLI; GEOBACILLUS KAUSTOPHILUS;

EID: 57449100055     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00654-08     Document Type: Article

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