-
1
-
-
34547855136
-
Cell proliferation and death: Forgotten features of chronic lymphocytic leukemia B cells
-
Chiorazzi N. Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cells. Best Pract Res Clin Haematol 2007;20:399-413.
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, pp. 399-413
-
-
Chiorazzi, N.1
-
2
-
-
32644435470
-
How I treat refractory CLL
-
Montserrat E, Moreno C, Esteve J, Urbano-Ispizua A, Gine E, Bosch F. How I treat refractory CLL. Blood 2006;107:1276-83.
-
(2006)
Blood
, vol.107
, pp. 1276-1283
-
-
Montserrat, E.1
Moreno, C.2
Esteve, J.3
Urbano-Ispizua, A.4
Gine, E.5
Bosch, F.6
-
3
-
-
34547967320
-
Fludarabine: A review of its use in non-Hodgkin's lymphoma
-
Anderson VR, Perry CM. Fludarabine: a review of its use in non-Hodgkin's lymphoma. Drugs 2007;67:1633-55.
-
(2007)
Drugs
, vol.67
, pp. 1633-1655
-
-
Anderson, V.R.1
Perry, C.M.2
-
4
-
-
0032830965
-
In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia
-
Bellosillo B, Villamor N, Colomer D, Pons G, Montserrat E, Gil J. In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia. Blood 1999;94:2836-43.
-
(1999)
Blood
, vol.94
, pp. 2836-2843
-
-
Bellosillo, B.1
Villamor, N.2
Colomer, D.3
Pons, G.4
Montserrat, E.5
Gil, J.6
-
5
-
-
0030322149
-
In vitro sensitivity of chronic lymphocytic leukemia B-cells to fludarabine, 2-chlorodeoxyadenosine and chlorambucil: Correlation with clinicohematological and immunophenotypic features
-
Morabito F, Stelitano C, Callea I, Filangeri M, Oliva B, Sculli G, et al. In vitro sensitivity of chronic lymphocytic leukemia B-cells to fludarabine, 2-chlorodeoxyadenosine and chlorambucil: correlation with clinicohematological and immunophenotypic features. Haematologica 1996;81:224-31.
-
(1996)
Haematologica
, vol.81
, pp. 224-231
-
-
Morabito, F.1
Stelitano, C.2
Callea, I.3
Filangeri, M.4
Oliva, B.5
Sculli, G.6
-
6
-
-
0032844150
-
The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia
-
Pettitt AR, Sherrington PD, Cawley JC. The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia. Br J Haematol 1999;106:1049-51.
-
(1999)
Br J Haematol
, vol.106
, pp. 1049-1051
-
-
Pettitt, A.R.1
Sherrington, P.D.2
Cawley, J.C.3
-
7
-
-
0013040873
-
Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562
-
Dumontet C, Fabianowska-Majewska K, Mantincic D, Callet BE, Tigaud I, Gandhi V, et al. Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562. Br J Haematol 1999;106: 78-85.
-
(1999)
Br J Haematol
, vol.106
, pp. 78-85
-
-
Dumontet, C.1
Fabianowska-Majewska, K.2
Mantincic, D.3
Callet, B.E.4
Tigaud, I.5
Gandhi, V.6
-
8
-
-
0034994444
-
Nucleoside analogues: Mechanisms of drug resistance and reversal strategies
-
Galmarini CM, Mackey JR, Dumontet C. Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia 2001;15:875-90.
-
(2001)
Leukemia
, vol.15
, pp. 875-890
-
-
Galmarini, C.M.1
Mackey, J.R.2
Dumontet, C.3
-
9
-
-
1242272722
-
The equilibrative nucleoside transporter family, SLC29
-
Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD. The equilibrative nucleoside transporter family, SLC29. Pflugers Arch 2004;447:735-43.
-
(2004)
Pflugers Arch
, vol.447
, pp. 735-743
-
-
Baldwin, S.A.1
Beal, P.R.2
Yao, S.Y.3
King, A.E.4
Cass, C.E.5
Young, J.D.6
-
10
-
-
1242340288
-
The concentrative nucleoside transporter family, SLC28
-
Gray JH, Owen RP, Giacomini KM. The concentrative nucleoside transporter family, SLC28. Pflugers Arch 2004;447:728-34.
-
(2004)
Pflugers Arch
, vol.447
, pp. 728-734
-
-
Gray, J.H.1
Owen, R.P.2
Giacomini, K.M.3
-
11
-
-
1542503842
-
Nucleoside transporters in chronic lymphocytic leukaemia
-
Pastor-Anglada M, Molina-Arcas M, Casado FJ, Bellosillo B, Colomer D, Gil J. Nucleoside transporters in chronic lymphocytic leukaemia. Leukemia 2004;18:385-93.
-
(2004)
Leukemia
, vol.18
, pp. 385-393
-
-
Pastor-Anglada, M.1
Molina-Arcas, M.2
Casado, F.J.3
Bellosillo, B.4
Colomer, D.5
Gil, J.6
-
12
-
-
0037443633
-
Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia
-
Molina-Arcas M, Bellosillo B, Casado FJ, Montserrat E, Gil J, Colomer D, et al. Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia. Blood 2003;101:2328-34.
-
(2003)
Blood
, vol.101
, pp. 2328-2334
-
-
Molina-Arcas, M.1
Bellosillo, B.2
Casado, F.J.3
Montserrat, E.4
Gil, J.5
Colomer, D.6
-
13
-
-
19944428546
-
Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): Identification of fludarabine-sensitive and -insensitive populations
-
Mackey JR, Galmarini CM, Graham KA, Joy AA, Delmer A, Dabbagh L, et al. Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations. Blood 2005;105:767-74.
-
(2005)
Blood
, vol.105
, pp. 767-774
-
-
Mackey, J.R.1
Galmarini, C.M.2
Graham, K.A.3
Joy, A.A.4
Delmer, A.5
Dabbagh, L.6
-
14
-
-
19944427083
-
Equilibrative nucleoside transporter-2 (hENT2) protein expression correlates with ex vivo sensitivity to fludarabine in chronic lymphocytic leukemia (CLL) cells
-
Molina-Arcas M, Marce S, Villamor N, Huber-Ruano I, Casado FJ, Bellosillo B, et al. Equilibrative nucleoside transporter-2 (hENT2) protein expression correlates with ex vivo sensitivity to fludarabine in chronic lymphocytic leukemia (CLL) cells. Leukemia 2005;19:64-8.
-
(2005)
Leukemia
, vol.19
, pp. 64-68
-
-
Molina-Arcas, M.1
Marce, S.2
Villamor, N.3
Huber-Ruano, I.4
Casado, F.J.5
Bellosillo, B.6
-
15
-
-
33751085679
-
Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5′-DFUR in breast cancer MCF7 cells
-
Molina-Arcas M, Moreno-Bueno G, Cano-Soldado P, Hernandez-Vargas H, Casado FJ, Palacios J, et al. Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5′-DFUR in breast cancer MCF7 cells. Biochem Pharmacol 2006;72:1646-56.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1646-1656
-
-
Molina-Arcas, M.1
Moreno-Bueno, G.2
Cano-Soldado, P.3
Hernandez-Vargas, H.4
Casado, F.J.5
Palacios, J.6
-
16
-
-
0037406968
-
ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
-
Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, Rozman M, et al. ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 2003;348:1764-75.
-
(2003)
N Engl J Med
, vol.348
, pp. 1764-1775
-
-
Crespo, M.1
Bosch, F.2
Villamor, N.3
Bellosillo, B.4
Colomer, D.5
Rozman, M.6
-
17
-
-
0036721455
-
Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia
-
Bellosillo B, Villamor N, López-Guillermo A, Marcé S, Bosch F, Campo E, et al. Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia. Blood 2002;100:1810-6.
-
(2002)
Blood
, vol.100
, pp. 1810-1816
-
-
Bellosillo, B.1
Villamor, N.2
López-Guillermo, A.3
Marcé, S.4
Bosch, F.5
Campo, E.6
-
18
-
-
18744409028
-
Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia
-
Bosch F, Ferrer A, Lopez-Guillermo A, Gine E, Bellosillo B, Villamor N, et al. Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia. Br J Haematol 2002;119:976-84.
-
(2002)
Br J Haematol
, vol.119
, pp. 976-984
-
-
Bosch, F.1
Ferrer, A.2
Lopez-Guillermo, A.3
Gine, E.4
Bellosillo, B.5
Villamor, N.6
-
19
-
-
0042121252
-
GEPAS: A web-based resource for microarray gene expression data analysis
-
Herrero J, Al-Shahrour F, Díaz-Uriarte R, Mateos A, Vaquerizas JM, Santoyo J, Dopazo J. GEPAS: a web-based resource for microarray gene expression data analysis. Nucleic Acids Res 2003;31:3461-7.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3461-3467
-
-
Herrero, J.1
Al-Shahrour, F.2
Díaz-Uriarte, R.3
Mateos, A.4
Vaquerizas, J.M.5
Santoyo, J.6
Dopazo, J.7
-
20
-
-
0142219312
-
Nucleoside transporter profiles in human pancreatic cancer cells: Role of hCNT1 in 2′,2′-difluorodeoxycytidine-induced cytotoxicity
-
Garcia-Manteiga J, Molina-Arcas M, Casado FJ, Mazo A, Pastor-Anglada M. Nucleoside transporter profiles in human pancreatic cancer cells: role of hCNT1 in 2′,2′-difluorodeoxycytidine-induced cytotoxicity. Clin Cancer Res 2003;9:5000-8.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5000-5008
-
-
Garcia-Manteiga, J.1
Molina-Arcas, M.2
Casado, F.J.3
Mazo, A.4
Pastor-Anglada, M.5
-
21
-
-
33745792969
-
Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma
-
Marce S, Molina-Arcas M, Villamor N, Casado FJ, Campo E, Pastor-Anglada M, et al. Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. Haematologica 2006;91:895-902.
-
(2006)
Haematologica
, vol.91
, pp. 895-902
-
-
Marce, S.1
Molina-Arcas, M.2
Villamor, N.3
Casado, F.J.4
Campo, E.5
Pastor-Anglada, M.6
-
22
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 2006;126:107-20.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
-
23
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai KR, Peterson BL, Appelbaum FR, Kolitz J, Elias L, Shepherd L, et al. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med 2000;343:1750-7.
-
(2000)
N Engl J Med
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Appelbaum, F.R.3
Kolitz, J.4
Elias, L.5
Shepherd, L.6
-
24
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993;74:957-67.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
25
-
-
40749128044
-
Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: High response rate and disease eradication
-
Bosch F, Ferrer A, Villamor N, Gonzalez M, Briones J, Gonzalez-Barca E, et al. Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication. Clin Cancer Res 2008;14:155-61.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 155-161
-
-
Bosch, F.1
Ferrer, A.2
Villamor, N.3
Gonzalez, M.4
Briones, J.5
Gonzalez-Barca, E.6
-
26
-
-
0028987180
-
p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic Bcell leukemias
-
Dohner H, Fischer K, Bentz M, Hansen K, Benner A, Cabot G, et al. p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic Bcell leukemias. Blood 1995;85:1580-9.
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Dohner, H.1
Fischer, K.2
Bentz, M.3
Hansen, K.4
Benner, A.5
Cabot, G.6
-
27
-
-
33947544426
-
Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US Intergroup phase III trial E2997
-
Grever MR, Lucas DM, Dewald GW, Neuberg DS, Reed JC, Kitada S, et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup phase III trial E2997. J Clin Oncol 2007;25:799-804.
-
(2007)
J Clin Oncol
, vol.25
, pp. 799-804
-
-
Grever, M.R.1
Lucas, D.M.2
Dewald, G.W.3
Neuberg, D.S.4
Reed, J.C.5
Kitada, S.6
-
28
-
-
0033028601
-
Purine analogues kill resting lymphocytes by p53-dependent and -independent mechanisms
-
Pettitt AR, Clarke AR, Cawley JC, Griffiths SD. Purine analogues kill resting lymphocytes by p53-dependent and -independent mechanisms. Br J Haematol 1999;105:986-8.
-
(1999)
Br J Haematol
, vol.105
, pp. 986-988
-
-
Pettitt, A.R.1
Clarke, A.R.2
Cawley, J.C.3
Griffiths, S.D.4
-
29
-
-
4444228658
-
Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response
-
Rosenwald A, Chuang EY, Davis RE, Wiestner A, Alizadeh AA, Arthur DC, et al. Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response. Blood 2004;104:1428-34.
-
(2004)
Blood
, vol.104
, pp. 1428-1434
-
-
Rosenwald, A.1
Chuang, E.Y.2
Davis, R.E.3
Wiestner, A.4
Alizadeh, A.A.5
Arthur, D.C.6
-
30
-
-
0345688175
-
Nucleoside anticancer drugs: The role of nucleoside transporters in resistance to cancer chemotherapy
-
Damaraju VL, Damaraju S, Young JD, Baldwin SA, MacKey J, Sawyer MB, et al. Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy. Oncogene 2003;22:7524-36.
-
(2003)
Oncogene
, vol.22
, pp. 7524-7536
-
-
Damaraju, V.L.1
Damaraju, S.2
Young, J.D.3
Baldwin, S.A.4
MacKey, J.5
Sawyer, M.B.6
-
31
-
-
34249899423
-
Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes
-
Smal C, Van Den NE, Maerevoet M, Poire X, Theate I, Bontemps F. Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes. Cancer Lett 2007;253:68-73.
-
(2007)
Cancer Lett
, vol.253
, pp. 68-73
-
-
Smal, C.V.D.N.1
Maerevoet, M.2
Poire, X.3
Theate, I.4
Bontemps, F.5
-
32
-
-
0036180689
-
Cytotoxicity of 2-chlorodeoxy-adenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: Significance of cellular nucleoside transporter content
-
Wright AM, Paterson AR, Sowa B, Akabutu JJ, Grundy PE, Gati WP. Cytotoxicity of 2-chlorodeoxy-adenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: significance of cellular nucleoside transporter content. Br J Haematol 2002;116:528-37.
-
(2002)
Br J Haematol
, vol.116
, pp. 528-537
-
-
Wright, A.M.1
Paterson, A.R.2
Sowa, B.3
Akabutu, J.J.4
Grundy, P.E.5
Gati, W.P.6
-
33
-
-
0030971066
-
Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein
-
Gati WP, Paterson AR, Larratt LM, Turner AR, Belch AR. Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein. Blood 1997;90:346-53.
-
(1997)
Blood
, vol.90
, pp. 346-353
-
-
Gati, W.P.1
Paterson, A.R.2
Larratt, L.M.3
Turner, A.R.4
Belch, A.R.5
-
34
-
-
0037441744
-
Differential mRNA expression of ara-C-metabolizing enzymes explains ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia
-
Stam RW, den Boer ML, Meijerink JP, Ebus ME, Peters GJ, Noordhuis P, et al. Differential mRNA expression of ara-C-metabolizing enzymes explains ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia. Blood 2003;101:1270-6.
-
(2003)
Blood
, vol.101
, pp. 1270-1276
-
-
Stam, R.W.1
den Boer, M.L.2
Meijerink, J.P.3
Ebus, M.E.4
Peters, G.J.5
Noordhuis, P.6
-
35
-
-
28644447388
-
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia
-
Hubeek I, Stam RW, Peters GJ, Broekhuizen R, Meijerink JP, van Wering ER, et al. The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. Br J Cancer 2005;93:1388-94.
-
(2005)
Br J Cancer
, vol.93
, pp. 1388-1394
-
-
Hubeek, I.1
Stam, R.W.2
Peters, G.J.3
Broekhuizen, R.4
Meijerink, J.P.5
van Wering, E.R.6
-
36
-
-
0036280996
-
In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia
-
Galmarini CM, Thomas X, Calvo F, Rousselot P, Rabilloud M, El Jaffari A, et al. In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia. Br J Haematol 2002;117:860-8.
-
(2002)
Br J Haematol
, vol.117
, pp. 860-868
-
-
Galmarini, C.M.1
Thomas, X.2
Calvo, F.3
Rousselot, P.4
Rabilloud, M.5
El Jaffari, A.6
-
37
-
-
6044267987
-
The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma
-
Spratlin J, Sangha R, Glubrecht D, Dabbagh L, Young JD, Dumontet C, et al. The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma. Clin Cancer Res 2004;10:6956-61.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6956-6961
-
-
Spratlin, J.1
Sangha, R.2
Glubrecht, D.3
Dabbagh, L.4
Young, J.D.5
Dumontet, C.6
-
38
-
-
0037165658
-
PKC regulation of the human equilibrative nucleoside transporter, hENT1
-
Coe I, Zhang Y, McKenzie T, Naydenova Z. PKC regulation of the human equilibrative nucleoside transporter, hENT1. FEBS Lett 2002;517:201-5.
-
(2002)
FEBS Lett
, vol.517
, pp. 201-205
-
-
Coe, I.1
Zhang, Y.2
McKenzie, T.3
Naydenova, Z.4
-
39
-
-
8644236778
-
Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors
-
Farre X, Guillen-Gomez E, Sanchez L, Hardisson D, Plaza Y, Lloberas J, et al. Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors. Int J Cancer 2004;112:959-66.
-
(2004)
Int J Cancer
, vol.112
, pp. 959-966
-
-
Farre, X.1
Guillen-Gomez, E.2
Sanchez, L.3
Hardisson, D.4
Plaza, Y.5
Lloberas, J.6
|