Adjuvant effect of di-(2-ethylhexyl) phthalate on asthma-like pathological changes in ovalbumin-immunised rats

Food and Agricultural Immunology

Volumn 19, Issue 4, 2008, Pages 351-362

  Yang, Guangtao ^a   Qiao, Yongkang ^a   Li, Bing ^a   Yang, Jiwen ^a   Liu, Dandan ^a   Yao, Hanchao ^a   Xu, Dongqun ^b   Yang, Xu ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Adjuvant effect; Asthma; Di (2 ethylhexyl)phthalate; Ovalbumin immunised rat

Indexed keywords

RATTUS; RATTUS NORVEGICUS;

EID: 57349175918     PISSN: 09540105     EISSN: 14653443     Source Type: Journal    
DOI: 10.1080/09540100802545869     Document Type: Article

References (45)

1. Ahn J.H., Kim, C.H, Kim, Y.H., Lee, S.Y., Kim, Y.K., Kim, K.H., et al. (2007). Inflammatory and remodeling events in asthma with chronic exposure to house dust mites: A murine model. Journal of Korean Medical Science, 22, 1026-1033.
2. ATSDR (2001). Toxicological profile for di-n-butyl phthalate. Atlanta, GA: Agency for Toxic Substances and Disease Registry.
3. ATRDR (2002). Toxicological profile for di(2-ethylhexyl)phthalate (DEHP). Atlanta, GA: Agency for Toxic Substances and Disease Registry.
4. Bornehag, C.G., Lundgren, B., Weschler, C.J., Sigsgaard, T., Hagerhed-Engman, L., & Sundell, J. (2005). Phthalates in indoor dust and their association with building characteristics. Environmental Health Perspectives, 113, 1399-1404.
5. Bornehag, C.G., Sundell, J., Weschler, C.J., Sigsgaard, T., Lundgren, B., Hasselgren, M., et al. (2004). The association between asthma and allergic symptoms in children and phthalates in house dust: A nested case-control study. Environmental Health Perspectives, 112, 1393-1397.
6. Boulet, L.P., & Sterk, P.J. (2007). A new series on airway remodeling. European Respiratory Journal, 29, 231-232.
7. Butala, J.H., David, R.M., Gans, G., McKee, R.H., Guo, T.L., Peachee, V.L., et al. (2004). Phthalate treatment does not influence levels of IgE or Th2 cytokines in B6C3F1 mice. Toxicology, 201, 77-85.
8. Calafat, A.M., Needham, L.L., Silva, M.J., & Lambert, G. (2004). Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit. Pediatrics, 113, e429-e434.
9. Chen, G., Zhou, D.H., & Kang, B.C. (2001). A comparative study on cockroach and ovalbumin sensitizations and challenge responses in Hartley guinea-pigs. Respiration Physiology, 125, 239-247.
10. Cho, S.H., Reponen, T., Bernstein, D.I., Olds, R., Levin, L., Liu, X., et al. (2006). The effect of home characteristics on dust antigen concentrations and loads in homes. Science of the Total Environment, 371, 31-43.
11. Delfino, R.J. (2002). Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research. Environmental Health Perspectives, 110, 573-589.
12. Devereux, G., & Seaton, A. (2005). Diet as a risk factor for atopy and asthma. Allergy and Clinical Immunology, 115, 1109-1117.
13. Doull, J., Cattley, R., Elcombe, C., Lake, B.G., Swenberg, J., Wilkinson, C., et al. (1999). A cancer risk assessment of di(2-ethylhexyl)phthalate: Application of the new U.S. EPA risk assessment guidelines. Regulatory Toxicology and Pharmacology, 29, 327-357.
14. Drazen, J.M., Finn, P.W., & De Sanctis, G.T. (1999). Mouse models of airway responsiveness: Physiological basis of observed outcomes and analysis of selected examples using these outcome indicators. Annual Review of Physiology, 61, 593-625.
15. Ebtekar, M. (2006). Air pollution induced asthma and alterations in cytokine patterns. Iranian Journal of Allergy, Asthma and Immunology, 5, 47-56.
16. Elias, J.A. (2000). Airway remodeling in asthma: Unanswered questions. American Journal of Respiratory and Critical Care Medicine, 161, S168-S171.
17. FDA. (2001). Safety assessment of di(2-ethylhexyl)phthalate (DEHP) released from PVC medical devices. Rockville, MD: Center for Devices and Radiological Health, U.S. Food and Drug Administration. Retrieved August 11, 2007, from http://www.fda.gov/cdrh/ost/dehp-pvc.pdf.
18. Gillis, H.L., & Lutchen, K.R. (1999). Airway remodeling in asthma amplifies heterogeneities in smooth muscle shortening causing hyperresponsiveness. Journal of Applied Physiology, 86, 2001-2012.
19. Green, R., Hauser, R., Calafat, A.M., Weuve, J., Schettler, T., & Ringer, S., et al. (2005). Use of di-(2-ethylhexyl) phthalate containing medical products and urinary levels of mono-(2-ethylhexyl) phthalate in neonatal intensive care unit infants. Environmental Health Perspectives, 113, 1222-1225.
20. Huber, W.W., Grasl-Kraupp, B., & Schulte-Hermann, R. (1996). Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk. Critical Reviews in Toxicology, 26, 365-481.
21. Jaakkola, J.J., Oie, L., Nafstad, P., Botten, G., Samuelsen, S.O., & Magnus, P. (1999). Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway. American Journal of Public Health, 89, 188-192.
22. Jaakkola, J.J., Verkasalo, P.K., & Jaakkola, N. (2000). Plastic wall materials in the home and respiratory health in young children. American Journal of Public Health, 90, 797-799.
23. Karol, M.H. (1994). Animal models of occupational asthma. European Respiratory Journal, 7, 555-568.
24. Kimber, I. (1998). Allergy, asthma and the environment: An introduction. Toxicology Letters, 102, 301-306.
25. Koch, H.M., Drexler, H., & Angerer, J. (2003). An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population. International Journal of Hygiene and Environmental Health, 206, 77-83.
26. Koch, H.M., Rossbach, B., Drexler, H., & Angerer, J. (2003). Internal exposure of the general population to DEHP and other phthalates-determination of secondary and primary phthalate monoester metabolites in urine. Environmental Research, 93, 177-185.
27. Kohn, M.C., Parham, F., Masten, S.A., Portier, C.J., Shelby, M.D., Brock, J.W., et al. (2000). Human exposure estimates for phthalates. Environmental Health Perspectives, 108, A440-A442.
28. Larsen, S.T., Hansen, J.S., Hansen, E.K., Clausen, P.A., & Nielsen, G.D. (2007). Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice. Toxicology, 235, 119-129.
29. Larsen, S.T., Lund, R.M., Nielsen, G.D., Thygesen, P., & Poulsen, M.O. (2001). Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB/c mice. Toxicology Letters, 125, 11-18.
30. Leigh, R., Ellis, R., Wattie, J., Southam, D.S., De Hoogh, M., Gauldie, J., et al. (2002). Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. American Journal of Respiratory Cell and Molecular Biology, 27, 526-535.
31. Lorz, P.M., Towae, F.K., Enke, W., Jäckh, R., Bhargava, N., & Hillesheim, W. (2002). Phthalic acid and derivatives. Ullmann's encyclopedia of industrial chemistry. Weinheim, Germany: Wiley-VCH.
32. Meek, M.E., & Chan, P.K.L. (1994). Bis(2-ethylhexyl)phthalate: evaluation of risks to health from environmental exposure in Canada. Journal of Environmental Science Health. Part C. Environmental Carcinogenisis and Ecotoxicology Reviews, 12, 179-194.
33. NTP-CERHR. (2003). Monograph on the potential human reproductive and developmental effects of butyl benzyl phthalate (BBP). Research Triangle Park, NC: National Toxicology Program, Center for the Evaluation of Risks to Human Reproduction. Retrieved December 1, 2006, from http://cerhr.niehs.nih.gov/ chemicals/phthalates/bb-phthalate/BBP_Monograph_Final.pdf
34. Oie, L., Hersoug, L.G., & Madsen, J.O. (1997). Residential exposure to plasticizers and its possible role in the pathogenesis of asthma. Environmental Health Perspectives, 105, 972-978.
35. Platts-Mills, A.E., & Woodfolk, J.A. (1997). Rise in asthma cases. Science, 278, 997-1001.
36. Ring, J. (1997). Allergy and modern society: Does 'western life style' promote the development of allergies? International Archives of Allergy and Immunology, 113, 7-10.
37. Ring, J., Krämer, U., & Behrendt, H. (2005). A critical approach to the hygiene hypothesis. Clinical & Experimental Allergy Reviews, 4, 40-44.
38. Rockville, M.D. (2001). Safety assessment of di(2-ethylhexyl)phthalate (DEHP) released from PVC medical devices. Center for Devices and Radiological Health, U.S. Food and Drug Administration. Retrieved December 11, 2006, from http://www.fda.gov/cdrh/ost/dehppvc.pdf.
39. Schettler, T. (2006). Human exposure to phthalates via consumer products. International Journal of Andrology, 29, 134-139.
40. Shea, K.M. (2003). American academy of pediatrics committee on environmental health. pediatric exposure and potential toxicity of phthalate plasticizers. Pediatrics, 111, 1467-1474.
41. Silva, M.J., Barr, D.B., Reidy, J.A., Malek, N.A., Hodge, C.C., & Caudill, S.P., et al. (2004). Urinary levels of seven phthalate metabolites in the US population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environmental Health Perspectives, 112, 331-338.
42. Snapper, C.M., Finkelman, F.D., & Paul, W.E. (1988). Regulation of IgG1 and IgE production by interleukin 4. Immunological Reviews, 102, 51-75.
43. Strachan, D. (1996). Socioeconomic factors and the development of allergy. Toxicology Letters, 86, 199-203.
44. WHO (2004). Prevention of allergy and allergic asthma. World Allergy Organization Project Report and Guidelines. Chemical Immunology and Allergy. Basel, Switzerland: Karger.
45. Yamauchi, K. (2006). Airway remodeling in asthma and its influence on clinical pathophysiology. Tohoku Journal of Experimental Medicine, 209, 75-87.