Surgical treatment for epilepsy: Too little, too late?

JAMA

Volumn 300, Issue 21, 2008, Pages 2548-2550

  Engel, Jerome ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; EDITORIAL; ELECTROENCEPHALOGRAM; HUMAN; INTRACTABLE EPILEPSY; MAGNETOENCEPHALOGRAPHY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TEMPORAL LOBE EPILEPSY; WORLD HEALTH ORGANIZATION;

EID: 57349168225     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2008.756     Document Type: Editorial

References (22)

1. Murray GJ, Lopez AD. Global Comparative Assessments in the Health Sector: Disease Burden, Expenditure, Intervention Packages. Geneva, Switzerland: World Health Organization; 1994.
2. Berg AT. Understanding the delay before epilepsy surgery: who develops intractable focal epilepsy and when? CNS Spectr. 2004;9(2):136-144.
3. Begley CE, Famulari M, Annegers JF, et al. The cost of epilepsy in the United States: an estimate from population-based clinical and survey data. Epilepsia. 2000;41(3):342-351.
4. Semah F, Picot M-C, Adam C, et al. Is the underlying cause of epilepsy a major prognostic factor for recurrence? Neurology. 1998;51(5):1256-1262.
5. Engel J Jr. Etiology as a risk factor for medically refractory epilepsy: a case for early surgical intervention. Neurology. 1998;51(5):1243-1244.
6. Engel J Jr, Van Ness P, Rasmussen TB, Ojemann LM. Outcome with respect to epileptic seizures. In: Engel J Jr, ed. Surgical Treatment of the Epilepsies. 2nd ed. New York, NY: Raven Press; 1993:609-621.
7. Engel J Jr, Wiebe S, French J, et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Neurology. 2003;60(4):538-547.
8. Wiebe S, Blume WT, Girvin JP, Eliasziw M. A randomized, controlled trial of surgery for temporal lobe epilepsy. N Engl J Med. 2001;345(5):311-318.
9. Engel J Jr, Shewmon DA. Overview: who should be considered a surgical candidate? In: Engel J Jr, ed. Surgical Treatment of the Epilepsies. 2nd ed. New York, NY: Raven Press; 1993:23-34.
10. Berg AT, Langfitt J, Shinnar S, et al. How long does it take for partial epilepsy to become intractable? Neurology. 2003;60(2):186-190.
11. Engel J Jr. Finally, a randomized controlled trial of epilepsy surgery. N Engl J Med. 2001;345(5):365-367.
12. Sperling MR. The consequences of uncontrolled epilepsy. CNS Spectr. 2004;9(2):98-109.
13. Choi H, Sell RL, Lenert L, et al. Epilepsy surgery for pharmacoresistant temporal lobe epilepsy: a decision analysis. JAMA. 2008;300(21):2497- 2505.
14. Engel J Jr, Cahan L. Potential relevance of kindling to human partial epilepsy. In: Wada J, ed. Kindling 3. New York, NY: Raven Press; 1986:37-51.
15. Engel J Jr. Current concepts: surgery for seizures. N Engl J Med. 1996;334(10):647-652.
16. Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med. 2000;342(5):314-319.
17. Bauer J, Buchmüller L, Reuber M, Burr W. Which patients become seizure free with antiepileptic drugs? an observational study in 821 patients with epilepsy. Acta Neurol Scand. 2008;117(1):55-59.
18. Callaghan BC, Anaud K, Hesdorffer D, Hauser WA, French JA. Likelihood of seizure remission in an adult population with refractory epilepsy. Ann Neurol. 2007;62(4):382-389.
19. Liimatainen SP, Raitanen JA, Ylinen AM, Peltola MA, Peltola JT. The benefit of active drug trials is dependent on the aetiology in refractory focal epilepsy [published correction in J Neurol Neurosurg Psychiatry. 2008;79(9):1086]. J Neurol Neurosurg Psychiatry. 2008;79(7):808-812.
20. Luciano AL, Shorvon SD. Results of treatment changes in patients with apparently drug-resistant chronic epilepsy. Ann Neurol. 2007;62(4):375-381.
21. Spencer SS, Sperling MR, Shewman DA, Kahane P. Intracranial electrodes. In: Engel J Jr, ed. Epilepsy: A Comprehensive Textbook. Philadelphia, PA: Wolters Kluwer; 2008:1791-1815.
22. Schomer DL, Black PM. A 24-year-old woman with intractable seizures: review of surgery for epilepsy. JAMA. 2008;300(21):2527-2538.