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Volumn 123, Issue 12, 2008, Pages 2931-2938

Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21WAF1/CIP1 dependent

Author keywords

Apoptosis; Cell cycle; Oral cancer; OSU03012; p21WAF1 CIP1

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CELECOXIB; CELL CYCLE PROTEIN; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1; OSU 03012; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 57349154375     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23895     Document Type: Article
Times cited : (12)

References (47)
  • 4
    • 33644766747 scopus 로고    scopus 로고
    • Cytotoxicity of a non-cyclooxygenase-2 inhibitory derivative of celecoxib in non-small-cell lung cancer A549 cells
    • Tong Z, Wu X, Chen CS, Kehrer JP. Cytotoxicity of a non-cyclooxygenase-2 inhibitory derivative of celecoxib in non-small-cell lung cancer A549 cells. Lung Cancer 2006;52:117-24.
    • (2006) Lung Cancer , vol.52 , pp. 117-124
    • Tong, Z.1    Wu, X.2    Chen, C.S.3    Kehrer, J.P.4
  • 7
    • 20844434173 scopus 로고    scopus 로고
    • Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance
    • Tseng PH, Lin HP, Zhu J, Chen KF, Hade EM, Young DC, Byrd JC, Grever M, Johnson K, Druker BJ, Chen CS. Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance. Blood 2005;105:4021-7.
    • (2005) Blood , vol.105 , pp. 4021-4027
    • Tseng, P.H.1    Lin, H.P.2    Zhu, J.3    Chen, K.F.4    Hade, E.M.5    Young, D.C.6    Byrd, J.C.7    Grever, M.8    Johnson, K.9    Druker, B.J.10    Chen, C.S.11
  • 8
    • 42249092819 scopus 로고    scopus 로고
    • Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor
    • Weng SC, Kashida Y, Kulp SK, Wang D, Brueggemeier RW, Shapiro CL, Chen CS. Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor. Mol Cancer Ther 2008;7:800-8.
    • (2008) Mol Cancer Ther , vol.7 , pp. 800-808
    • Weng, S.C.1    Kashida, Y.2    Kulp, S.K.3    Wang, D.4    Brueggemeier, R.W.5    Shapiro, C.L.6    Chen, C.S.7
  • 14
    • 38449111862 scopus 로고    scopus 로고
    • Cell cycle deregulation in breast cancer: Insurmountable chemoresistance or Achilles' heel?
    • Lambert L, Keyomarsi K. Cell cycle deregulation in breast cancer: insurmountable chemoresistance or Achilles' heel? Adv Exp Med Biol 2007;608:52-69.
    • (2007) Adv Exp Med Biol , vol.608 , pp. 52-69
    • Lambert, L.1    Keyomarsi, K.2
  • 16
    • 0030766184 scopus 로고    scopus 로고
    • Ineffectiveness of the presence of h-ras/p53 combination mutations in squamous cell carcinoma cells to induce the conversion of a nontumorigenic to a tumorigenic tumor type
    • Lee H, Li D, Prior T, Casto BC, Weghorst CM, Shuler CF, Milo GE. Ineffectiveness of the presence of h-ras/p53 combination mutations in squamous cell carcinoma cells to induce the conversion of a nontumorigenic to a tumorigenic tumor type. Cell Biol Toxicol 1997;13:419-34.
    • (1997) Cell Biol Toxicol , vol.13 , pp. 419-434
    • Lee, H.1    Li, D.2    Prior, T.3    Casto, B.C.4    Weghorst, C.M.5    Shuler, C.F.6    Milo, G.E.7
  • 17
    • 0033796588 scopus 로고    scopus 로고
    • The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck
    • Nylander K, Dabelsteen E, Hall PA. The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck. J Oral Pathol Med 2000;29:413-25.
    • (2000) J Oral Pathol Med , vol.29 , pp. 413-425
    • Nylander, K.1    Dabelsteen, E.2    Hall, P.A.3
  • 19
    • 0032167646 scopus 로고    scopus 로고
    • Expression of p21 (Waf1/Cip1) in head and neck cancer in relation to proliferation, differentiation, p53 status and cyclin D1 expression
    • Van Oijen MG, Tilanus MG, Medema RH, Slootweg PJ. Expression of p21 (Waf1/Cip1) in head and neck cancer in relation to proliferation, differentiation, p53 status and cyclin D1 expression. J Oral Pathol Med 1998;27:367-75.
    • (1998) J Oral Pathol Med , vol.27 , pp. 367-375
    • Van Oijen, M.G.1    Tilanus, M.G.2    Medema, R.H.3    Slootweg, P.J.4
  • 22
    • 33645224637 scopus 로고    scopus 로고
    • Grow-ING Age-ING and Die-ING: ING proteins link cancer, senescence and apoptosis
    • Russell M, Berardi P, Gong W, Riabowol K. Grow-ING Age-ING and Die-ING: ING proteins link cancer, senescence and apoptosis. Exp Cell Res 2006;312:951-61.
    • (2006) Exp Cell Res , vol.312 , pp. 951-961
    • Russell, M.1    Berardi, P.2    Gong, W.3    Riabowol, K.4
  • 23
    • 0029079228 scopus 로고
    • Apoptosis in antitumor strategies: Modulation of cell cycle or differentiation
    • Darzynkiewicz Z. Apoptosis in antitumor strategies: modulation of cell cycle or differentiation. J Cell Biochem 1995;58:151-9.
    • (1995) J Cell Biochem , vol.58 , pp. 151-159
    • Darzynkiewicz, Z.1
  • 24
    • 0031455518 scopus 로고    scopus 로고
    • Modulation of chemosensitivity through altered expression of cell cycle regulatory genes in cancer
    • Hochhauser D. Modulation of chemosensitivity through altered expression of cell cycle regulatory genes in cancer. Anticancer Drugs 1997;8:903-10.
    • (1997) Anticancer Drugs , vol.8 , pp. 903-910
    • Hochhauser, D.1
  • 25
    • 1242271208 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells
    • Kulp SK, Yang YT, Hung CC, Chen KF, Lai JP, Tseng PH, Fowble JW, Ward PJ, Chen CS. 3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. Cancer Res 2004;64:1444-51.
    • (2004) Cancer Res , vol.64 , pp. 1444-1451
    • Kulp, S.K.1    Yang, Y.T.2    Hung, C.C.3    Chen, K.F.4    Lai, J.P.5    Tseng, P.H.6    Fowble, J.W.7    Ward, P.J.8    Chen, C.S.9
  • 27
    • 0033860894 scopus 로고    scopus 로고
    • Differential growth responses of normal, premalignant, and malignant human oral epithelial cells by chemopreventive agents
    • D'Ambrosio SM, D'Ambrosio REG, Milo GE, Casto BC, Kelloff GJ, Steele VE. Differential growth responses of normal, premalignant, and malignant human oral epithelial cells by chemopreventive agents. Anticancer Res 2000;20:2273-80.
    • (2000) Anticancer Res , vol.20 , pp. 2273-2280
    • D'Ambrosio, S.M.1    D'Ambrosio, R.E.G.2    Milo, G.E.3    Casto, B.C.4    Kelloff, G.J.5    Steele, V.E.6
  • 28
    • 0022549344 scopus 로고
    • A method for isolating large numbers of viable disaggregated cells from various human tissues for cell culture establishment
    • Gibson-D'Ambrosio RE, Samuel M, D'Ambrosio SM. A method for isolating large numbers of viable disaggregated cells from various human tissues for cell culture establishment. In Vitro 1986;22:529-34.
    • (1986) In Vitro , vol.22 , pp. 529-534
    • Gibson-D'Ambrosio, R.E.1    Samuel, M.2    D'Ambrosio, S.M.3
  • 29
    • 1842484279 scopus 로고    scopus 로고
    • Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells
    • Horner SM, DeFilippis RA, Manuelidis L, DiMaio D. Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. J Virol 2004;78:4063-73.
    • (2004) J Virol , vol.78 , pp. 4063-4073
    • Horner, S.M.1    DeFilippis, R.A.2    Manuelidis, L.3    DiMaio, D.4
  • 30
    • 19544370181 scopus 로고    scopus 로고
    • Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries
    • Han C, Ding H, Casto BC, Stoner GD, D'Ambrosio SM. Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries. Nutr Cancer 2005;51:207-17.
    • (2005) Nutr Cancer , vol.51 , pp. 207-217
    • Han, C.1    Ding, H.2    Casto, B.C.3    Stoner, G.D.4    D'Ambrosio, S.M.5
  • 31
    • 0242332090 scopus 로고    scopus 로고
    • Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1
    • Ding H, Han C, Gibson-D'Ambrosio R, Steele VE, D'Ambrosio SM. Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1. Int J Cancer 2003;107:830-6.
    • (2003) Int J Cancer , vol.107 , pp. 830-836
    • Ding, H.1    Han, C.2    Gibson-D'Ambrosio, R.3    Steele, V.E.4    D'Ambrosio, S.M.5
  • 32
    • 57349087818 scopus 로고    scopus 로고
    • OSU03012 activates Erk1/2 and cdk2/cyclin A leading to the accumulation of cells in the S-phase and apoptosis
    • in press
    • Ding H, Han C, Guo D, Wang D, Chen CS, D'Ambrosio SM. OSU03012 activates Erk1/2 and cdk2/cyclin A leading to the accumulation of cells in the S-phase and apoptosis. Int J Cancer 2008;(in press).
    • (2008) Int J Cancer
    • Ding, H.1    Han, C.2    Guo, D.3    Wang, D.4    Chen, C.S.5    D'Ambrosio, S.M.6
  • 34
    • 38449113943 scopus 로고    scopus 로고
    • Human papillomavirus in cervical and head-and-neck cancer
    • Psyrri A, DiMaio D. Human papillomavirus in cervical and head-and-neck cancer. Nat Clin Pract Oncol 2008;5:24-31.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 24-31
    • Psyrri, A.1    DiMaio, D.2
  • 35
    • 0027991315 scopus 로고
    • Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines
    • Min BM, Baek JH, Shin KH, Gujuluva CN, Cherrick HM, Park NH. Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines. Eur J Cancer B Oral Oncol 1994;30B:338-45.
    • (1994) Eur J Cancer B Oral Oncol , vol.30 B , pp. 338-345
    • Min, B.M.1    Baek, J.H.2    Shin, K.H.3    Gujuluva, C.N.4    Cherrick, H.M.5    Park, N.H.6
  • 37
    • 0038339635 scopus 로고    scopus 로고
    • p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax
    • Kawata S, Ariumi Y, Shimotohno K. p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax. J Virol 2003;77:7291-9.
    • (2003) J Virol , vol.77 , pp. 7291-7299
    • Kawata, S.1    Ariumi, Y.2    Shimotohno, K.3
  • 38
    • 1842481018 scopus 로고    scopus 로고
    • Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells
    • Nguyen DM, Schrump WD, Chen GA, Tsai W, Nguyen P, Trepel JB, Schrump DS. Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells. Clin Cancer Res 2004;10:1813-25.
    • (2004) Clin Cancer Res , vol.10 , pp. 1813-1825
    • Nguyen, D.M.1    Schrump, W.D.2    Chen, G.A.3    Tsai, W.4    Nguyen, P.5    Trepel, J.B.6    Schrump, D.S.7
  • 39
    • 30044440857 scopus 로고    scopus 로고
    • Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress
    • Rodriguez R, Meuth M. Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress. Mol Biol Cell 2006;17:402-12.
    • (2006) Mol Biol Cell , vol.17 , pp. 402-412
    • Rodriguez, R.1    Meuth, M.2
  • 40
    • 0032510026 scopus 로고    scopus 로고
    • Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells
    • Lu Y, Yamagishi N, Yagi T, Takebe H. Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells. Oncogene 1998;16:705-12.
    • (1998) Oncogene , vol.16 , pp. 705-712
    • Lu, Y.1    Yamagishi, N.2    Yagi, T.3    Takebe, H.4
  • 42
    • 33845777950 scopus 로고    scopus 로고
    • p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation
    • Sohn D, Essmann F, Schulze-Osthoff K, Janicke RU. p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation. Cancer Res 2006;66:11254-62.
    • (2006) Cancer Res , vol.66 , pp. 11254-11262
    • Sohn, D.1    Essmann, F.2    Schulze-Osthoff, K.3    Janicke, R.U.4
  • 43
    • 11144352722 scopus 로고    scopus 로고
    • Golsteyn RM. Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle. Cancer Lett 2005;217:129-38.
    • Golsteyn RM. Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle. Cancer Lett 2005;217:129-38.
  • 44
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret O. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 2003;13:65-70.
    • (2003) Trends Cell Biol , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 45
    • 2342598475 scopus 로고    scopus 로고
    • The role of p27Kip1 in proteasome inhibitor induced apoptosis
    • Drexler HC. The role of p27Kip1 in proteasome inhibitor induced apoptosis. Cell Cycle 2003;2:438-41.
    • (2003) Cell Cycle , vol.2 , pp. 438-441
    • Drexler, H.C.1
  • 46
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L, Slingerland JM. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 2008;8:253-67.
    • (2008) Nat Rev Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 47
    • 20144384882 scopus 로고    scopus 로고
    • Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 2005;65:3980-5.
    • Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 2005;65:3980-5.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.