메뉴 건너뛰기




Volumn 76, Issue 12, 2008, Pages 5524-5534

Vibrio cholerae flagellins induce toll-like receptor 5-mediated interleukin-8 production through mitogen-activated protein kinase and NF-κB activation

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA VACCINE; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; RECOMBINANT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TOLL LIKE RECEPTOR 5;

EID: 57349138815     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00843-08     Document Type: Article
Times cited : (52)

References (58)
  • 2
    • 43049176799 scopus 로고    scopus 로고
    • IL-1beta expression in Int407 is induced by flagellin of Vibrio cholerae through TLR5 mediated pathway
    • Bandyopadhaya, A., M. Sarkar, and K. Chaudhuri. 2008. IL-1beta expression in Int407 is induced by flagellin of Vibrio cholerae through TLR5 mediated pathway. Microb. Pathog. 44:524-536.
    • (2008) Microb. Pathog , vol.44 , pp. 524-536
    • Bandyopadhaya, A.1    Sarkar, M.2    Chaudhuri, K.3
  • 3
    • 0036800129 scopus 로고    scopus 로고
    • Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-κB and MAP kinase pathways and the upregulated expression of interleukin 8
    • Berin, M. C., A. Darfeuille-Michaud, L. J. Egan, Y. Miyamoto, and M. F. Kagnoff. 2002. Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-κB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell. Microbiol. 4:635-648.
    • (2002) Cell. Microbiol , vol.4 , pp. 635-648
    • Berin, M.C.1    Darfeuille-Michaud, A.2    Egan, L.J.3    Miyamoto, Y.4    Kagnoff, M.F.5
  • 4
    • 0037371245 scopus 로고    scopus 로고
    • The Afa/Dr adhesins of diffusely adhering Escherichia coli stimulate interleukin-8 secretion, activate mitogen-activated protein kinases, and promote polymorphonuclear transepithelial migration in T84 polarized epithelial cells
    • Betis, F., P. Brest, V. Hofman, J. Guignot, M. F. Bernet-Camard, B. Rossi, A. Servin, and P. Hofman. 2003. The Afa/Dr adhesins of diffusely adhering Escherichia coli stimulate interleukin-8 secretion, activate mitogen-activated protein kinases, and promote polymorphonuclear transepithelial migration in T84 polarized epithelial cells. Infect. Immun. 71:1068-1074.
    • (2003) Infect. Immun , vol.71 , pp. 1068-1074
    • Betis, F.1    Brest, P.2    Hofman, V.3    Guignot, J.4    Bernet-Camard, M.F.5    Rossi, B.6    Servin, A.7    Hofman, P.8
  • 5
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274:10689-10692.
    • (1999) J. Biol. Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 6
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis, R. J. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 7
    • 0037174919 scopus 로고    scopus 로고
    • Two nonadjacent regions in enteroaggregative Escherichia coli flagellin are required for activation of Toll-like receptor 5
    • Donnelly, M. A., and T. S. Steiner. 2002. Two nonadjacent regions in enteroaggregative Escherichia coli flagellin are required for activation of Toll-like receptor 5. J. Biol. Chem. 277:40456-40461.
    • (2002) J. Biol. Chem , vol.277 , pp. 40456-40461
    • Donnelly, M.A.1    Steiner, T.S.2
  • 8
    • 0026411101 scopus 로고
    • Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector
    • Donnenberg, M. S., and J. B. Kaper. 1991. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect. Immun. 59:4310-4317.
    • (1991) Infect. Immun , vol.59 , pp. 4310-4317
    • Donnenberg, M.S.1    Kaper, J.B.2
  • 10
    • 0001494888 scopus 로고
    • The nature of the gastrointestinal lesion in Asiatic cholera and its relation to pathogenesis: A biopsy study
    • Gangarosa, E. J., W. R. Beisel, C. Benyajati, H. Sprinz, and P. Piyaratn. 1960. The nature of the gastrointestinal lesion in Asiatic cholera and its relation to pathogenesis: a biopsy study. Am. J. Trop. Med. Hyg. 9:125-135.
    • (1960) Am. J. Trop. Med. Hyg , vol.9 , pp. 125-135
    • Gangarosa, E.J.1    Beisel, W.R.2    Benyajati, C.3    Sprinz, H.4    Piyaratn, P.5
  • 11
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
    • Gewirtz, A. T., T. A. Navas, S. Lyons, P. J. Godowski, and J. L. Madara. 2001. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167: 1882-1885.
    • (2001) J. Immunol , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 13
    • 17144462135 scopus 로고    scopus 로고
    • Heidelberg, J. F., J. A. Eisen, W. C. Nelson, R. A. Clayton, M. L. Gwinn, R. J. Dodson, D. H. Haft, E. K. Hickey, J. D. Peterson, L. Umayam, S. R. Gill, K. E. Nelson, T. D. Read, H. Tettelin, D. Richardson, M. D. Ermolaeva, J. Vamathevan, S. Bass, H. Qin, I. Dragoi, P. Sellers, L. McDonald, T. Utterback, R. D. Fleishmann, W. C. Nierman, O. White, S. L. Salzberg, H. O. Smith, R. R. Colwell, J. J. Mekalanos, J. C. Venter, and C. M. Fraser. 2000. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406:477-483.
    • Heidelberg, J. F., J. A. Eisen, W. C. Nelson, R. A. Clayton, M. L. Gwinn, R. J. Dodson, D. H. Haft, E. K. Hickey, J. D. Peterson, L. Umayam, S. R. Gill, K. E. Nelson, T. D. Read, H. Tettelin, D. Richardson, M. D. Ermolaeva, J. Vamathevan, S. Bass, H. Qin, I. Dragoi, P. Sellers, L. McDonald, T. Utterback, R. D. Fleishmann, W. C. Nierman, O. White, S. L. Salzberg, H. O. Smith, R. R. Colwell, J. J. Mekalanos, J. C. Venter, and C. M. Fraser. 2000. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406:477-483.
  • 16
    • 4043111231 scopus 로고    scopus 로고
    • Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activation
    • Khan, M. A., J. Kang, and T. S. Steiner. 2004. Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activation. Immunology 112:651-660.
    • (2004) Immunology , vol.112 , pp. 651-660
    • Khan, M.A.1    Kang, J.2    Steiner, T.S.3
  • 17
    • 0031951605 scopus 로고    scopus 로고
    • Differential regulation of multiple flagellins in Vibrio cholerae
    • Klose, K. E., and J. J. Mekalanos. 1998. Differential regulation of multiple flagellins in Vibrio cholerae. J. Bacteriol. 180:303-316.
    • (1998) J. Bacteriol , vol.180 , pp. 303-316
    • Klose, K.E.1    Mekalanos, J.J.2
  • 20
    • 0002778525 scopus 로고
    • Volunteer studies in development of vaccines against cholera and enterotoxigenic Escherichia coli: A review
    • T. Holme, J. Holmgren, M. H. Merson, and R. Mollby ed, Elsevier, Amsterdam, The Netherlands
    • Levine, M. M., R. E. Black, M. L. Clements, D. R. Nalin, L. Cisneros, and R. A. Finkelstein. 1981. Volunteer studies in development of vaccines against cholera and enterotoxigenic Escherichia coli: a review, p. 443-459. In T. Holme, J. Holmgren, M. H. Merson, and R. Mollby (ed.), Acute enteric infections in children. New prospects for treatment and prevention. Elsevier, Amsterdam, The Netherlands.
    • (1981) Acute enteric infections in children. New prospects for treatment and prevention , pp. 443-459
    • Levine, M.M.1    Black, R.E.2    Clements, M.L.3    Nalin, D.R.4    Cisneros, L.5    Finkelstein, R.A.6
  • 21
    • 0021058990 scopus 로고
    • New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
    • Levine, M. M., J. B. Kaper, R. E. Black, and M. L. Clements. 1983. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev. 47:510-550.
    • (1983) Microbiol. Rev , vol.47 , pp. 510-550
    • Levine, M.M.1    Kaper, J.B.2    Black, R.E.3    Clements, M.L.4
  • 22
    • 0023789781 scopus 로고
    • Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR
    • Levine, M. M., J. B. Kaper, D. Herrington, J. Ketley, G. Losonsky, C. O. Tacket, B. Tall, and S. Cryz. 1988. Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR. Lancet. ii:467-470.
    • (1988) Lancet , vol.2 , pp. 467-470
    • Levine, M.M.1    Kaper, J.B.2    Herrington, D.3    Ketley, J.4    Losonsky, G.5    Tacket, C.O.6    Tall, B.7    Cryz, S.8
  • 24
    • 0029118461 scopus 로고
    • Ultrastructural changes in the upper small intestinal mucosa in patients with cholera
    • Mathan, M. M., G. Chandy, and V. I. Mathan. 1995. Ultrastructural changes in the upper small intestinal mucosa in patients with cholera. Gastroenterology 109:422-430.
    • (1995) Gastroenterology , vol.109 , pp. 422-430
    • Mathan, M.M.1    Chandy, G.2    Mathan, V.I.3
  • 25
    • 0031883544 scopus 로고    scopus 로고
    • Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium
    • McCormick, B. A., C. A. Parkos, S. P. Colgan, D. K. Carnes, and J. L. Madara. 1998. Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium. J. Immunol. 160:455-466.
    • (1998) J. Immunol , vol.160 , pp. 455-466
    • McCormick, B.A.1    Parkos, C.A.2    Colgan, S.P.3    Carnes, D.K.4    Madara, J.L.5
  • 26
    • 0014122519 scopus 로고
    • Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235
    • McIntire, F. C., H. W. Sievert, G. H. Barlow, R. A. Finley, and A. Y. Lee. 1967. Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235. Biochemistry 6:2363-2372.
    • (1967) Biochemistry , vol.6 , pp. 2363-2372
    • McIntire, F.C.1    Sievert, H.W.2    Barlow, G.H.3    Finley, R.A.4    Lee, A.Y.5
  • 27
    • 0037226519 scopus 로고    scopus 로고
    • Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance
    • Medvedev, A. E., and S. N. Vogel. 2003. Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance. J. Endotoxin Res. 9:60-64.
    • (2003) J. Endotoxin Res , vol.9 , pp. 60-64
    • Medvedev, A.E.1    Vogel, S.N.2
  • 28
    • 0027244956 scopus 로고
    • Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells
    • Menard, R., P. J. Sansonetti, and C. Parsot. 1993. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J. Bacteriol. 175:5899-5906.
    • (1993) J. Bacteriol , vol.175 , pp. 5899-5906
    • Menard, R.1    Sansonetti, P.J.2    Parsot, C.3
  • 29
    • 0027495118 scopus 로고
    • CVD110, an attenuated Vibrio cholerae O1 El Tor live oral vaccine strain
    • Michalski, J., J. E. Galen, A. Fasano, and J. B. Kaper. 1993. CVD110, an attenuated Vibrio cholerae O1 El Tor live oral vaccine strain. Infect. Immun. 61:4462-4468.
    • (1993) Infect. Immun , vol.61 , pp. 4462-4468
    • Michalski, J.1    Galen, J.E.2    Fasano, A.3    Kaper, J.B.4
  • 32
    • 1242294430 scopus 로고    scopus 로고
    • Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro
    • Murthy, K. G., A. Deb, S. Goonesekera, C. Szabo, and A. L. Salzman. 2004. Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro. J. Biol. Chem. 279:5667- 5675.
    • (2004) J. Biol. Chem , vol.279 , pp. 5667-5675
    • Murthy, K.G.1    Deb, A.2    Goonesekera, S.3    Szabo, C.4    Salzman, A.L.5
  • 33
    • 57349169616 scopus 로고    scopus 로고
    • Norris, H. T. 1974. The pathology of cholera, p. 169-187. In B. Burrows (ed.), Cholera. Saunders, Philadelphia, PA.
    • Norris, H. T. 1974. The pathology of cholera, p. 169-187. In B. Burrows (ed.), Cholera. Saunders, Philadelphia, PA.
  • 34
    • 0017140452 scopus 로고
    • A bioptic study of gastrointestinal mucosa in cholera patients during an epidemic in southern Italy
    • Pastore, G., G. Schiraldi, G. Fera, E. Sforza, and O. Schiraldi. 1976. A bioptic study of gastrointestinal mucosa in cholera patients during an epidemic in southern Italy. Am. J. Dig. Dis. 21:613-617.
    • (1976) Am. J. Dig. Dis , vol.21 , pp. 613-617
    • Pastore, G.1    Schiraldi, G.2    Fera, G.3    Sforza, E.4    Schiraldi, O.5
  • 35
    • 0345830645 scopus 로고    scopus 로고
    • Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induces increases in innate cells and inflammatory mediators at the mucosal surface of the gut
    • Qadri, F., T. R. Bhuiyan, K. K. Dutta, R. Raqib, M. S. Alam, N. H. Alam, A. M. Svennerholm, and M. M. Mathan. 2004. Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induces increases in innate cells and inflammatory mediators at the mucosal surface of the gut. Gut 53:62-69.
    • (2004) Gut , vol.53 , pp. 62-69
    • Qadri, F.1    Bhuiyan, T.R.2    Dutta, K.K.3    Raqib, R.4    Alam, M.S.5    Alam, N.H.6    Svennerholm, A.M.7    Mathan, M.M.8
  • 38
    • 0021847804 scopus 로고
    • Identification and occurrence of Vibrio cholerae flagellar core proteins in isolated outer membrane
    • Richardson, K., and C. D. Parker. 1985. Identification and occurrence of Vibrio cholerae flagellar core proteins in isolated outer membrane. Infect. Immun. 47:674-679.
    • (1985) Infect. Immun , vol.47 , pp. 674-679
    • Richardson, K.1    Parker, C.D.2
  • 39
    • 0035160163 scopus 로고    scopus 로고
    • Differential interleukin-8 response of intestinal epithelial cell line to reactogenic and nonreactogenic candidate vaccine strains of Vibrio cholerae
    • Rodriguez, B. L., A. Rojas, J. Campos, T. Ledon, E. Valle, W. Toledo, and R. Fando. 2001. Differential interleukin-8 response of intestinal epithelial cell line to reactogenic and nonreactogenic candidate vaccine strains of Vibrio cholerae. Infect. Immun. 69:613-616.
    • (2001) Infect. Immun , vol.69 , pp. 613-616
    • Rodriguez, B.L.1    Rojas, A.2    Campos, J.3    Ledon, T.4    Valle, E.5    Toledo, W.6    Fando, R.7
  • 40
    • 0024972526 scopus 로고
    • Protein structure. Chaperones, paperones
    • Sambrook, J., and M. J. Gething. 1989. Protein structure. Chaperones, paperones. Nature 342:224-225.
    • (1989) Nature , vol.342 , pp. 224-225
    • Sambrook, J.1    Gething, M.J.2
  • 41
    • 0242653921 scopus 로고    scopus 로고
    • Activation and suppression of the proinflammatory immune response by Vibrio cholerae toxins
    • Satchell, K. J. 2003. Activation and suppression of the proinflammatory immune response by Vibrio cholerae toxins. Microbes Infect. 5:1241-1247.
    • (2003) Microbes Infect , vol.5 , pp. 1241-1247
    • Satchell, K.J.1
  • 42
    • 0029907913 scopus 로고    scopus 로고
    • Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophils
    • Savkovic, S. D., A. Koutsouris, and G. Hecht. 1996. Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophils. Infect. Immun. 64:4480-4487.
    • (1996) Infect. Immun , vol.64 , pp. 4480-4487
    • Savkovic, S.D.1    Koutsouris, A.2    Hecht, G.3
  • 44
    • 0029978911 scopus 로고    scopus 로고
    • New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and O139 Vibrio cholerae
    • Silva, T. M., M. A. Schleupner, C. O. Tacket, T. S. Steiner, J. B. Kaper, R. Edelman, and R. Guerrant. 1996. New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and O139 Vibrio cholerae. Infect. Immun. 64:2362-2364.
    • (1996) Infect. Immun , vol.64 , pp. 2362-2364
    • Silva, T.M.1    Schleupner, M.A.2    Tacket, C.O.3    Steiner, T.S.4    Kaper, J.B.5    Edelman, R.6    Guerrant, R.7
  • 45
    • 0021027842 scopus 로고
    • A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in Gram negative bacteria
    • Simon, R., U. Prefiefer, and A. Puhler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram negative bacteria. Bio/Technology 1:784-791.
    • (1983) Bio/Technology , vol.1 , pp. 784-791
    • Simon, R.1    Prefiefer, U.2    Puhler, A.3
  • 46
  • 47
    • 33846829490 scopus 로고    scopus 로고
    • How flagellin and Toll-like receptor 5 contribute to enteric infection
    • Steiner, T. S. 2007. How flagellin and Toll-like receptor 5 contribute to enteric infection. Infect. Immun. 75:545-552.
    • (2007) Infect. Immun , vol.75 , pp. 545-552
    • Steiner, T.S.1
  • 48
    • 0033945681 scopus 로고    scopus 로고
    • Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells
    • Steiner, T. S., J. P. Nataro, C. E. Poteet-Smith, J. A. Smith, and R. L. Guerrant. 2000. Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells. J. Clin. Investig. 105:1769-1777.
    • (2000) J. Clin. Investig , vol.105 , pp. 1769-1777
    • Steiner, T.S.1    Nataro, J.P.2    Poteet-Smith, C.E.3    Smith, J.A.4    Guerrant, R.L.5
  • 49
    • 0027524750 scopus 로고
    • Safety and immunogenicity of live oral cholera vaccine candidate CVD 110, a ΔctxA Δzot Δace derivative of El Tor Ogawa Vibrio cholerae
    • Tacket, C. O., G. Losonsky, J. P. Nataro, S. J. Cryz, R. Edelman, A. Fasano, J. Michalski, J. B. Kaper, and M. M. Levine. 1993. Safety and immunogenicity of live oral cholera vaccine candidate CVD 110, a ΔctxA Δzot Δace derivative of El Tor Ogawa Vibrio cholerae. J. Infect. Dis. 168:1536-1540.
    • (1993) J. Infect. Dis , vol.168 , pp. 1536-1540
    • Tacket, C.O.1    Losonsky, G.2    Nataro, J.P.3    Cryz, S.J.4    Edelman, R.5    Fasano, A.6    Michalski, J.7    Kaper, J.B.8    Levine, M.M.9
  • 50
    • 4844224383 scopus 로고    scopus 로고
    • Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-κB and proinflammatory gene program activation in intestinal epithelial cells
    • Tallant, T., A. Deb, N. Kar, J. Lupica, M. J. de Veer, and J. A. DiDonato. 2004. Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-κB and proinflammatory gene program activation in intestinal epithelial cells. BMC Microbiol. 4:33.
    • (2004) BMC Microbiol , vol.4 , pp. 33
    • Tallant, T.1    Deb, A.2    Kar, N.3    Lupica, J.4    de Veer, M.J.5    DiDonato, J.A.6
  • 51
    • 0028986193 scopus 로고
    • NF-kappa B: A lesson in family values
    • Thanos, D., and T. Maniatis. 1995. NF-kappa B: a lesson in family values. Cell 80:529-532.
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 52
    • 0027225631 scopus 로고
    • Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette
    • Trucksis, M., J. E. Galen, J. Michalski, A. Fasano, and J. B. Kaper. 1993. Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette. Proc. Natl. Acad. Sci. USA 90:5267-5271.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5267-5271
    • Trucksis, M.1    Galen, J.E.2    Michalski, J.3    Fasano, A.4    Kaper, J.B.5
  • 54
    • 40749144875 scopus 로고    scopus 로고
    • Decreased potency of the Vibrio cholerae sheathed flagellum to trigger host innate immunity
    • Yoon, S. S., and J. J. Mekalanos. 2008. Decreased potency of the Vibrio cholerae sheathed flagellum to trigger host innate immunity. Infect. Immun. 76:1282-1288.
    • (2008) Infect. Immun , vol.76 , pp. 1282-1288
    • Yoon, S.S.1    Mekalanos, J.J.2
  • 56
    • 34249716382 scopus 로고    scopus 로고
    • Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells
    • Zhao, L., M. J. Kwon, S. Huang, J. Y. Lee, K. Fukase, N. Inohara, and D. H. Hwang. 2007. Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells. J. Biol. Chem. 282:11618-11628.
    • (2007) J. Biol. Chem , vol.282 , pp. 11618-11628
    • Zhao, L.1    Kwon, M.J.2    Huang, S.3    Lee, J.Y.4    Fukase, K.5    Inohara, N.6    Hwang, D.H.7
  • 58
    • 0037378135 scopus 로고    scopus 로고
    • Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells
    • Zhou, X., J. A. Girón, A. G. Torres, J. A. Crawford, E. Negrete, S. N. Vogel, and J. B. Kaper. 2003. Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells. Infect. Immun. 71:2120-2129.
    • (2003) Infect. Immun , vol.71 , pp. 2120-2129
    • Zhou, X.1    Girón, J.A.2    Torres, A.G.3    Crawford, J.A.4    Negrete, E.5    Vogel, S.N.6    Kaper, J.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.