Ultrasound techniques for drug delivery in cardiovascular medicine

Current Drug Discovery Technologies

Volumn 5, Issue 4, 2008, Pages 328-332

  Landini, Luigi ^a   Santarelli, Maria Filomena ^a   Landini, Linda ^a   Positano, Vincenzo ^b  

^a UNIVERSITY OF PISA   (Italy)

^b FONDAZIONE TOSCANA GABRIELE MONASTERIO   (Italy)

Author keywords

Cardiovascular disease; Contrast echocardiography; Targeted contrast agents; Therapeutic ultrasound

Indexed keywords

DOXORUBICIN; ECHO CONTRAST MEDIUM; PERFLUTREN; RECOMBINANT SCATTER FACTOR; VASCULOTROPIN 165;

ACOUSTICS; CONTRAST ECHOCARDIOGRAPHY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; GENE DELIVERY SYSTEM; HUMAN; MICROBUBBLE; NONHUMAN; PRIORITY JOURNAL; REVIEW; ULTRASOUND;

ANIMALS; CARDIOVASCULAR AGENTS; CARDIOVASCULAR DISEASES; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; GENE THERAPY; HUMANS; MICROBUBBLES; ULTRASONOGRAPHY;

EID: 57349137368     PISSN: 15701638     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016308786733573     Document Type: Review

References (40)

1. Cronan J.J.: Ultrasound: is there a future in diagnostic imaging? J. Am. Coll. Radiol. 3(9), 645-656, (2006).
2. Moreau J.F.: Ultrasound: is there a future in diagnostic imaging? J. Am. Coll. Radiol. 4(1), 78-79, (2007).
3. Lindner J.R., Song J., Christiansen J., Klibanov A.L., Xu F., Ley K.: Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation 104, 2107-2112, (2001).
4. Bekeredjian R., Grayburn P.A., Shohet R.V.: Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine. J. Am. Coll. Cardiol. 45(3), 329-335, (2005).
5. Unger E.C., Matsunaga T.O., McCreery T., Schumann P., Sweitzer R., Quigley R.: Therapeutic applications of microbubbles. E. J. Radiology 42, 160-168, (2002).
6. Keirolowoon A., Dayton P.A., Lum A.F.H., Little E., Paoli E.E., Zheng H., Ferrara K.W.: Acoustically-active microbubbles conjugated to liposomes: characterization of a proposed drug delivery vehicle. J. Control. Release 118, 275-284, (2007).
7. Tsutsui J.M., Xie F., Porter R.T.: The use of microbubbles to target drug delivery. Cardiovas. Ultrasound 2, 23-29, (2004).
8. Müller O.J., Katus H.A., Bekeredjian R.: Targeting the heart with gene therapy-optimized gene delivery methods. Cardiovasc Res 73(3), 453-462, (2007).
9. Wu J.: Temperature rise generated by ultrasound in the presence of contrast agent. Ultrasound Med Biol. 24(2), 267-274, (1998).
10. Husseini G.A., Runyan C.M., Pitt W.P.: Investigating the mechanism of acoustically activated uptake of drugs from Pluronic micelles. BMC Cancer 2, 1-6, (2002).
11. Dijkmans P.A., Juffermans L.J., Musters R.J., van Wamel A., ten Cate F.J., van Gilst W., Visser C.A., de Jong N., et al.: Microbubbles and ultrasound: from diagnosis to therapy. Eur. J. Echocardiogr. 5(4), 245-256, (2004).
12. Starritt H.C., Duck F.A., Humphrey V.F.: An experimental investigation of streaming in pulsed diagnostic ultrasound beams. Ultrasound Med. Biol. 15, 363-373, (1989).
13. Barnett N.B., Ter Haar G.R., Ziskin M.C., Nyborg W.L., Maeda K., Bang J.: Current status of research on biophysical effects of ultrasound. Ultrasound Med. Biol. 20, 205-218, (1994).
14. Schlicher R.K., Radhakrishna H., Tolentino T.P., Apkarian R.P., Zarnitsyn V., Prausnitz M.R.: Mechanisms of intracellular delivery by acoustic cavitation. Ultrasound Med. Biol. 32(6), 915-924, (2006).
15. O'Brien W.D., Jr.: Ultrasound-biophysics mechanisms. Prog. Biophys. Mol. Biol. 93(1-3), 212-255, (2007).
16. De Jong N.: Mechanical index. J. Echocardiography 3(1), 73-74, (2002).
17. Church C.C.: Frequency, pulse length, and the mechanical index. Acoustics Res. Lett. Online 6(3), 162-168, (2005).
18. Van Bavel E.: Effects of shear stress on endothelial cells: Possible relevance for ultrasound applications. Prog. Biophys. Mol. Biol. 93(1-3), 374-383, (2007).
19. Sundaram J., Mellein B.R., Mitragotri S.: An experimental and theoretical analysis of ultrasound-induced permeabilization of cell membranes. J. Biophys. 84(5), 3087-3101, (2003).
20. Stieger S.M., Caskey C.F., Adamson R.H., Qin S., Curry F.R., Wisner E.R., Ferrara K.W.: Enhancement of vascular permeability with low-frequency contrast-enhanced ultrasound in the chorioallantoic membrane model. Radiology 243(1), 112-121, (2007).
21. Van Wamel A., Kooiman K., Emmer M., ten Cate F.J., Versluis M., de Jong N.: Ultrasound microbubble induced endothelial cell permeability. J. Control Release 116(2), e100-e102, (2006).
22. Mukherjee D., Wong J., Griffin B., Ellis S.G., Porter T., Sen S., Thomas J.D.: Ten-fold augmentation of endothelial uptake of vascular endothelial growth factor with ultrasound after systemic administration. J. Am. Coll. Cardiol. 35, 1678-1686, (2000).
23. Larrue V.: Ultrasound-assisted thrombolysis in acute ischemic stroke. Presse Med. 34(17), 1254-1256, (2005).
24. Postema M., Schmitz G.: Ultrasonic bubbles in medicine: Influence of the shell. Ultrasonics Sonochemistry 14, 438-444, (2007).
25. Liu Y., Miyoshi H., Nakamura M.: Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Control. Release 114, 89-99, (2006).
26. Smith D., Porter T., Martinez J., Huang S., Macdonald R., Mcpherson D., Holland C.: Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound Med. Biol. 33(5), 797-809, (2007).
27. Taniyama Y., Tachibana K., Hiraoka K., Aoki M., Yamamoto S., Matsumoto K., Nakamura T., Ogihara T., et al.: Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther. 9(6), 372-380, (2002).
28. Mehier-Humbert S., Bettinger T., Yan F., Guy R.H.: Plasma membrane poration induced by ultrasound exposure: implication for drug delivery. J. Control. Release 104(1), 213-222, (2005).
29. Tran T.A., Le Guennec J.Y., Bougnoux P., Tranquart F., Bouakaz A.: Characterization of cell membrane response to ultrasound activated microbubbles. IEEE Trans Ultrason Ferroelectr. Freq. Control. 55(1), 43-49, (2008).
30. Kumon R.E., Aehle M., Sabens D., Parikh P., Kourennyi D., Deng CX.: Ultrasound-induced calcium oscillations and waves in Chinese hamster ovary cells in the presence of microbubbles. Biophys. J. 93(6), L29-31, (2007).
31. Hallow D.M., Mahajan A.D., Prausnitz M.R.: Ultrasonically targeted delivery into endothelial and smooth muscle cells in ex vivo arteries. J. Control. Release 118: 285-293, (2007).
32. Oh H., Chi X., Bradfute S.B., Mishina Y., Pocius J., Michael L.H., Behringer R.R., Schwartz R.J., et al.: Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann. NY Acad. Sci. 1015, 182-189, (2004).
33. Masayoshi I., Yasushi A., Takashi N., Keizo M., Yasuhiro S., Yuming Z.: Hepatocyte growth factor delivered by ultrasound-mediated destruction of microbubbles induces proliferation of cardiomyocytes and amelioration of left ventricular contractile function in doxorubicin-induced cardiomyopathy. Stem Cells 23, 1589-1597, (2005).
34. Bekeredjian R., Chen S., Frenkel P.A., Grayburn P.A., Shohet R.V.: Ultrasound targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart. Circulation 108, 1022-1026, (2003).
35. Korpanty G., Chen S., Shohet R.V., Ding J., Yang B., Frenkel P.A., Grayburn P.A.: Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles. Gene Ther. 12, 1305-1312, (2005).
36. Kondo I., Ohmori K., Oshita A., Takeuchi H., Fuke S., Shinomiya K., Noma T., Namba T., et al.: Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction. J. Am. Coll. Cardiol. 44, 644-653, (2004).
37. Bekeredjian R., Chen S., Pan W., Grayburn P.A., Shohet R.V.: Effects of ultrasound-targeted microbubble destruction on cardiac gene expression. Ultrasound Med. Biol. 30, 539-543, (2004).
38. Mitragotri S.: Healing sound: the use of ultrasound in drug delivery and other therapeutic applications. Nat. Rev. Drug Discov. 4(3), 255-260, (2005).
39. Anderson D.R., Tsutsui J.M., Xie F., Radio S.J., Porter T.R.: The role of complement in the adherence of microbubbles to dysfunctional arterial endothelium and atherosclerotic plaque. Cardiovasc. Res. 73, 597-606, (2007).
40. Porter T.R., Xie F., Knapp D., Iversen P., Marky L.A., Tsutsui J.M., Maiti S., Lof M.: Targeted vascular delivery of antisense molecules using intravenous microbubbles. Cardiovasc. Revasc. Med. 7(1), 25-33, (2006).