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Volumn 34, Issue 12, 2008, Pages 1356-1367

Formulation and evaluation of secnidazole or doxycycline dento-oral gels

Author keywords

Doxycycline; Mucoadhesive polymers; Periodontitis; Release study; Rheological properties; Secnidazole

Indexed keywords

CARBOMER; CHLORHEXIDINE; DOXYCYCLINE; ELUGEL; EUDRAGIT; MICONAZ; MICONAZOLE; SECNIDAZOLE; UNCLASSIFIED DRUG;

EID: 57349128951     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802122944     Document Type: Article
Times cited : (14)

References (55)
  • 2
    • 0034924241 scopus 로고    scopus 로고
    • Determination of minimum inhibitory concentrations
    • Andrews, J. M. (2001). Determination of minimum inhibitory concentrations. J. Antimicrob. Chemother., 48, 5-16.
    • (2001) J. Antimicrob. Chemother , vol.48 , pp. 5-16
    • Andrews, J.M.1
  • 4
    • 4444384402 scopus 로고    scopus 로고
    • Rheological, mucoadhesive and release properties of Carbopol gels in hydrophilic cosolvents
    • Bonacucina, G., Martelli, S., & Palmieri, G. F. (2004). Rheological, mucoadhesive and release properties of Carbopol gels in hydrophilic cosolvents. Int. J. Pharm., 282, 115-130.
    • (2004) Int. J. Pharm , vol.282 , pp. 115-130
    • Bonacucina, G.1    Martelli, S.2    Palmieri, G.F.3
  • 5
    • 29244477903 scopus 로고    scopus 로고
    • Rheological, adhesive and release characterization of semisolid Carbopol/tetraglycol systems
    • Bonacucina, G., Cespi, M., Misici-Falzi. M., & Palmieri G. F. (2006). Rheological, adhesive and release characterization of semisolid Carbopol/tetraglycol systems. Int. J. Pharm., 307, 129-140.
    • (2006) Int. J. Pharm , vol.307 , pp. 129-140
    • Bonacucina, G.1    Cespi, M.2    Misici-Falzi, M.3    Palmieri, G.F.4
  • 6
    • 16244377780 scopus 로고    scopus 로고
    • Oral bioadhesive drug delivery systems
    • Bruschi, M. L., & De Freitas, O. (2005). Oral bioadhesive drug delivery systems. Drug Dev. Ind. Pharm., 31, 293-310.
    • (2005) Drug Dev. Ind. Pharm , vol.31 , pp. 293-310
    • Bruschi, M.L.1    De Freitas, O.2
  • 7
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery: II. Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers
    • Ch'Ng, H. S., Park, H., Kelly, P., & Robinson, J. R. (1985). Bioadhesive polymers as platforms for oral controlled drug delivery: II. Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers. J. Pharm. Sci., 74, 399-405.
    • (1985) J. Pharm. Sci , vol.74 , pp. 399-405
    • Ch'Ng, H.S.1    Park, H.2    Kelly, P.3    Robinson, J.R.4
  • 8
    • 23144451894 scopus 로고    scopus 로고
    • Preparation and evaluation of a novel buccal adhesive system
    • article
    • Desai, K. G. H., & Kumar, T. M. P. (2004). Preparation and evaluation of a novel buccal adhesive system. AAPS Pharm. Sci. Tech., 5(3), article 35. http://www.aapspharmscitech.org.
    • (2004) AAPS Pharm. Sci. Tech , vol.5 , Issue.3 , pp. 35
    • Desai, K.G.H.1    Kumar, T.M.P.2
  • 9
    • 2642704985 scopus 로고    scopus 로고
    • Flow behavior of Carbopol 940 hydrogels, the influence of concentration and agitation time
    • Dolz, M., Herraez, M., Gozalez, F., & Diez, O. (1998). Flow behavior of Carbopol 940 hydrogels, the influence of concentration and agitation time. Pharmazie, 53(2), 126-130.
    • (1998) Pharmazie , vol.53 , Issue.2 , pp. 126-130
    • Dolz, M.1    Herraez, M.2    Gozalez, F.3    Diez, O.4
  • 10
    • 0033013346 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of anaerobic and capnophilic bacteria isolated from odontogenic abscesses and rapidly progressive periodontitis
    • Eick, S., Pfister, W., & Straube, E. (1999). Antimicrobial susceptibility of anaerobic and capnophilic bacteria isolated from odontogenic abscesses and rapidly progressive periodontitis. Int. J. Antimicrob. Agents, 12, 41-46.
    • (1999) Int. J. Antimicrob. Agents , vol.12 , pp. 41-46
    • Eick, S.1    Pfister, W.2    Straube, E.3
  • 11
    • 0034962252 scopus 로고    scopus 로고
    • In-vitro comparative study of buccal mucoadhesive performance of different polymeric films
    • Eouani, C., Piccerellea, P., Prinderrea, P., Bourret, E., & Joachim, J. (2001). In-vitro comparative study of buccal mucoadhesive performance of different polymeric films. Eur. J. Pharm. Biopharm., 52, 45-55.
    • (2001) Eur. J. Pharm. Biopharm , vol.52 , pp. 45-55
    • Eouani, C.1    Piccerellea, P.2    Prinderrea, P.3    Bourret, E.4    Joachim, J.5
  • 12
    • 0036848452 scopus 로고    scopus 로고
    • Systematic study of the flow behavior and mechanical properties of Carbopol Ultrez 10 hydroalcoholic gels
    • Fresno, M. J. C., Ramirez, A. D., & Jimenez, M. M. (2002). Systematic study of the flow behavior and mechanical properties of Carbopol Ultrez 10 hydroalcoholic gels. Eur. J. Pharm. Biopharm., 54, 329-335.
    • (2002) Eur. J. Pharm. Biopharm , vol.54 , pp. 329-335
    • Fresno, M.J.C.1    Ramirez, A.D.2    Jimenez, M.M.3
  • 13
    • 0036193457 scopus 로고    scopus 로고
    • Controlled local delivery of tetracyclines with polymer strips in the treatment of periodontitis
    • Friesen, L. R., Williams, K. B., Krause, L. S., & Killoy, W. J. (2002). Controlled local delivery of tetracyclines with polymer strips in the treatment of periodontitis. J. Periodontol., 73, 13-19.
    • (2002) J. Periodontol , vol.73 , pp. 13-19
    • Friesen, L.R.1    Williams, K.B.2    Krause, L.S.3    Killoy, W.J.4
  • 14
    • 0029913196 scopus 로고    scopus 로고
    • Secnidazole: A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis
    • Gillis, J. C., & Wiseman, L. R. (1996). Secnidazole: A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis. Drugs, 51, 621-638.
    • (1996) Drugs , vol.51 , pp. 621-638
    • Gillis, J.C.1    Wiseman, L.R.2
  • 16
    • 0028457303 scopus 로고
    • Antimicrobial strategies for treatment of the periodontal diseases
    • Goodson, J. M. (1994). Antimicrobial strategies for treatment of the periodontal diseases. Periodontol. 2000, 5, 142-168.
    • (1994) Periodontol. 2000 , vol.5 , pp. 142-168
    • Goodson, J.M.1
  • 17
    • 0025947549 scopus 로고
    • Preparation and evaluation of Eudragit gels. I: Eudragit Organogels containing drugs as rectal sustained-release preparations
    • Goto, S., Kawata, M., Suzuki, T., Kim, N., & Ito, C. (1991). Preparation and evaluation of Eudragit gels. I: Eudragit Organogels containing drugs as rectal sustained-release preparations. J. Pharm. Sci., 80, 958-961.
    • (1991) J. Pharm. Sci , vol.80 , pp. 958-961
    • Goto, S.1    Kawata, M.2    Suzuki, T.3    Kim, N.4    Ito, C.5
  • 18
    • 0028457308 scopus 로고
    • Microbial etiological agents of destructive periodontal disease
    • Haffajee, A. D., & Socransky, S. S. (1994). Microbial etiological agents of destructive periodontal disease. Periodontol. 2000, 5, 78-111.
    • (1994) Periodontol. 2000 , vol.5 , pp. 78-111
    • Haffajee, A.D.1    Socransky, S.S.2
  • 19
    • 0030955984 scopus 로고    scopus 로고
    • Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers
    • Jones, D. S., Woolfson, A. D., & Brown, A. F. (1997a). Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. Int. J. Pharm., 151, 223-233.
    • (1997) Int. J. Pharm , vol.151 , pp. 223-233
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 20
    • 0030913693 scopus 로고    scopus 로고
    • Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels
    • Jones, D. S., Woolfson, A. D., & Brown, A. F. (1997b). Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels. Pharm. Res., 14, 450-457.
    • (1997) Pharm. Res , vol.14 , pp. 450-457
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 21
    • 0030766318 scopus 로고    scopus 로고
    • Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties
    • Jones, D. S., Woolfson, A. D., Brown, A. F., & O'Neill, M. J. (1997). Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: in vitro release kinetics, syringeability, mechanical and mucoadhesive properties J. Control. Rel., 49, 71-79.
    • (1997) J. Control. Rel , vol.49 , pp. 71-79
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    O'Neill, M.J.4
  • 22
    • 0034601173 scopus 로고    scopus 로고
    • Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease
    • Jones, D. S., Woolfson, A. D., Brown, A. F., Coulter, W. A., McClelland, C., & Irwin, C. R. (2000). Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease. J. Control. Release, 67, 357-368.
    • (2000) J. Control. Release , vol.67 , pp. 357-368
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    Coulter, W.A.4    McClelland, C.5    Irwin, C.R.6
  • 23
    • 0030469411 scopus 로고    scopus 로고
    • Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases
    • Jones, D. S., Woolfson, A. D., Djokic, J., & Coulter, W. A. (1996). Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm. Res., 13, 1734-1738.
    • (1996) Pharm. Res , vol.13 , pp. 1734-1738
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3    Coulter, W.A.4
  • 24
    • 0002353804 scopus 로고    scopus 로고
    • Pathogenesis of periodontitis
    • J. Lindhe, T. Karring, & N. P. Lang Eds, Copenhagen: Munksgaard Intl Pub
    • Kinane, D. F., & Lindhe, J. (1997). Pathogenesis of periodontitis. In J. Lindhe, T. Karring, & N. P. Lang (Eds.). Clinical periodontology and implant dentistry, (pp. 189-225). Copenhagen: Munksgaard Intl Pub.
    • (1997) Clinical periodontology and implant dentistry , pp. 189-225
    • Kinane, D.F.1    Lindhe, J.2
  • 26
    • 0027345257 scopus 로고
    • Release behavior of bioactive agents from pH-sensitive hydrogels
    • Khare, A. R., & Peppas, N. A. (1993). Release behavior of bioactive agents from pH-sensitive hydrogels. J. Biomater. Sci. Polym. Ed., 4, 275-289.
    • (1993) J. Biomater. Sci. Polym. Ed , vol.4 , pp. 275-289
    • Khare, A.R.1    Peppas, N.A.2
  • 27
    • 0029965810 scopus 로고    scopus 로고
    • Development and evaluation of a mucoadhesive drug delivery system for dual-controlled delivery of Nonoxynol-9
    • Lee, C. H., & Chien, Y. W. (1996). Development and evaluation of a mucoadhesive drug delivery system for dual-controlled delivery of Nonoxynol-9. J. Control. Release, 39, 93-103.
    • (1996) J. Control. Release , vol.39 , pp. 93-103
    • Lee, C.H.1    Chien, Y.W.2
  • 28
    • 33947324513 scopus 로고    scopus 로고
    • Release characteristics of lidocaine from local implant of polyanionic and polycationic hydrogels
    • Liu, D. Z., Sheu, M. T., Chen, C. H., Yang, Y. R., & Ho, H. O. (2007). Release characteristics of lidocaine from local implant of polyanionic and polycationic hydrogels. J. Control. Release, 118(3), 333-339.
    • (2007) J. Control. Release , vol.118 , Issue.3 , pp. 333-339
    • Liu, D.Z.1    Sheu, M.T.2    Chen, C.H.3    Yang, Y.R.4    Ho, H.O.5
  • 29
    • 0025011073 scopus 로고
    • Randomized controlled trial of doxycycline in prevention of recurrent periodontitis in high-risk patients: Antimicrobial activity and collagenase inhibition
    • McCulloch, C. A. G., Birek, P., Overall, C. et al. (1990). Randomized controlled trial of doxycycline in prevention of recurrent periodontitis in high-risk patients: Antimicrobial activity and collagenase inhibition. J. Clin. Periodontol., 17, 616-622.
    • (1990) J. Clin. Periodontol , vol.17 , pp. 616-622
    • McCulloch, C.A.G.1    Birek, P.2    Overall, C.3
  • 30
    • 0025355398 scopus 로고
    • Bioadhesive analysis of controlled release systems: IV. An experimental method for testing the adhesion of microparticles with mucosa
    • Mikos, A. G., & Peppas, N. A. (1990). Bioadhesive analysis of controlled release systems: IV. An experimental method for testing the adhesion of microparticles with mucosa. J. Control. Release, 12, 31-37.
    • (1990) J. Control. Release , vol.12 , pp. 31-37
    • Mikos, A.G.1    Peppas, N.A.2
  • 31
    • 0027436645 scopus 로고
    • The influence of concentration on the release of drugs from gels and matrices containing Methocel®
    • Mitchell, K., Ford, J. L., Armstrong, D. J., Elliott, P. N. C., Rostron, C., & Hogan, J. E. (1993a). The influence of concentration on the release of drugs from gels and matrices containing Methocel®. Int. J. Pharm., 100, 155-163.
    • (1993) Int. J. Pharm , vol.100 , pp. 155-163
    • Mitchell, K.1    Ford, J.L.2    Armstrong, D.J.3    Elliott, P.N.C.4    Rostron, C.5    Hogan, J.E.6
  • 32
    • 0027489135 scopus 로고
    • The influence of drugs on the properties of gels and swelling characteristics of matrices containing methylcellulose or Hydroxypropylmethylcellulose
    • Mitchell, K., Ford, J. L., Armstrong, D. J., Elliott, P. N. C., Hogan, J. E., & Rostron, C. (1993b). The influence of drugs on the properties of gels and swelling characteristics of matrices containing methylcellulose or Hydroxypropylmethylcellulose. Int. J. Pharm., 100, 165-173.
    • (1993) Int. J. Pharm , vol.100 , pp. 165-173
    • Mitchell, K.1    Ford, J.L.2    Armstrong, D.J.3    Elliott, P.N.C.4    Hogan, J.E.5    Rostron, C.6
  • 33
    • 0031178395 scopus 로고    scopus 로고
    • Clinical response to local delivery of tetracycline in relation to overall and local periodontal conditions
    • Mombelli, A., Lehmann, B., Tonetti, M., & Lang, N. P. (1997). Clinical response to local delivery of tetracycline in relation to overall and local periodontal conditions. J. Clin. Periodontol., 24, 470-477.
    • (1997) J. Clin. Periodontol , vol.24 , pp. 470-477
    • Mombelli, A.1    Lehmann, B.2    Tonetti, M.3    Lang, N.P.4
  • 34
    • 0034629580 scopus 로고    scopus 로고
    • Muramatsu, M., Kanada, K., Nishida A., Ouchi, K., Saito, N., Yoshida, M., Shimoaka, A., Ozeki, T., Noriyasu, Yuasa, H., & Kanaya, Y. (2000). Application of Carbopol® to controlled release preparations I. Carbopol® as a novel coating material. Int. J. Pharm., 199, 77-83.
    • Muramatsu, M., Kanada, K., Nishida A., Ouchi, K., Saito, N., Yoshida, M., Shimoaka, A., Ozeki, T., Noriyasu, Yuasa, H., & Kanaya, Y. (2000). Application of Carbopol® to controlled release preparations I. Carbopol® as a novel coating material. Int. J. Pharm., 199, 77-83.
  • 36
    • 57349156014 scopus 로고    scopus 로고
    • National Committee for Clinical Laboratory Standards. (1997). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed. Approved standard (M7-A4). Wayne, PA: NCCLS.
    • National Committee for Clinical Laboratory Standards. (1997). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed. Approved standard (M7-A4). Wayne, PA: NCCLS.
  • 38
    • 0031613136 scopus 로고    scopus 로고
    • Characterisation of bioadhesives for periodontal and oral mucosal drug delivery
    • Needleman, I. G., Martin, G. P., & Smales, F. C. (1998). Characterisation of bioadhesives for periodontal and oral mucosal drug delivery, J. Clin. Periodontal., 25, 74-82.
    • (1998) J. Clin. Periodontal , vol.25 , pp. 74-82
    • Needleman, I.G.1    Martin, G.P.2    Smales, F.C.3
  • 39
    • 0031087411 scopus 로고    scopus 로고
    • A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients
    • Noyan, U., Yilmaz, S., Kuru, B., Kadir, T., Acar, O., & Buget, E. (1997). A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients. J. Clin. Periodontol., 24, 158-165.
    • (1997) J. Clin. Periodontol , vol.24 , pp. 158-165
    • Noyan, U.1    Yilmaz, S.2    Kuru, B.3    Kadir, T.4    Acar, O.5    Buget, E.6
  • 40
    • 0029626640 scopus 로고
    • Controlled release of lidocaine from injectable gels and efficacy in rat sciatic nerve block
    • Paavola, A., Yliruusi, J., Kajimoto, Y., Kalso, E., Wahlström, T., & Rosenberg, P. (1995). Controlled release of lidocaine from injectable gels and efficacy in rat sciatic nerve block. Pharm. Res., 12 (12), 1997-2002.
    • (1995) Pharm. Res , vol.12 , Issue.12 , pp. 1997-2002
    • Paavola, A.1    Yliruusi, J.2    Kajimoto, Y.3    Kalso, E.4    Wahlström, T.5    Rosenberg, P.6
  • 41
    • 14844290295 scopus 로고    scopus 로고
    • Metronidazole concentrations in plasma, saliva and periodontal pockets in patients with periodontitis
    • Pähkla, E. R., Koppel, T., Saag, M., & Pähkla, R. (2005). Metronidazole concentrations in plasma, saliva and periodontal pockets in patients with periodontitis. J. Clin. Peridontol., 32, 163-166.
    • (2005) J. Clin. Peridontol , vol.32 , pp. 163-166
    • Pähkla, E.R.1    Koppel, T.2    Saag, M.3    Pähkla, R.4
  • 42
    • 0028361592 scopus 로고
    • Structural rheology of model ointment
    • Pena, L. E., Lee, B. I., & Sternes, J. F. (1994). Structural rheology of model ointment. Pharm. Res., 11, 875-881.
    • (1994) Pharm. Res , vol.11 , pp. 875-881
    • Pena, L.E.1    Lee, B.I.2    Sternes, J.F.3
  • 43
    • 0021904208 scopus 로고
    • Analysis of Fickian and non-Fickian drug release from polymers
    • Peppas, N. A. (1985). Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv., 60, 110-111.
    • (1985) Pharm. Acta Helv , vol.60 , pp. 110-111
    • Peppas, N.A.1
  • 44
    • 0034601246 scopus 로고    scopus 로고
    • Local delivery of antimicrobial agents for the treatment of periodontal diseases
    • Schwach-Abdellaoui, K., Vivien-Castioni, N., & Gurny. R. (2000). Local delivery of antimicrobial agents for the treatment of periodontal diseases. Eur. J. Pharm. Biopharm., 50, 83-99.
    • (2000) Eur. J. Pharm. Biopharm , vol.50 , pp. 83-99
    • Schwach-Abdellaoui, K.1    Vivien-Castioni, N.2    Gurny, R.3
  • 45
    • 0029374114 scopus 로고
    • Cellular source, activation and inhibition of dental plaque collagenase
    • Sorsa, T., Ding, Y. L., Ongmam, T. et al. (1995). Cellular source, activation and inhibition of dental plaque collagenase. J. Clin. Periodontol., 22, 709-711.
    • (1995) J. Clin. Periodontol , vol.22 , pp. 709-711
    • Sorsa, T.1    Ding, Y.L.2    Ongmam, T.3
  • 46
    • 0141848152 scopus 로고    scopus 로고
    • Intoduction to Rheology
    • J. F. Steffe Ed, East Lansing, MI: Freeman Press
    • Steffe, J. F. (1996). Intoduction to Rheology. In J. F. Steffe (Ed.), Rheological methods in food process engineering (pp. 1-91). East Lansing, MI: Freeman Press.
    • (1996) Rheological methods in food process engineering , pp. 1-91
    • Steffe, J.F.1
  • 47
    • 0029916413 scopus 로고    scopus 로고
    • Rheological characterization of xanthan gum and hydroxypropylmethyl cellulose with respect to controlled-release drug delivery
    • Talukder, M. M., Vinckier, I., Moldenaers, P., & Kinget, R. (1996). Rheological characterization of xanthan gum and hydroxypropylmethyl cellulose with respect to controlled-release drug delivery. J. Pharm. Sci., 85(5), 537-540.
    • (1996) J. Pharm. Sci , vol.85 , Issue.5 , pp. 537-540
    • Talukder, M.M.1    Vinckier, I.2    Moldenaers, P.3    Kinget, R.4
  • 48
    • 0028810099 scopus 로고
    • An investigation into the rheological, dielectric and mucoadhesive properties of poly (acrylic acid) gel systems
    • Tamburic, S., & Craig, D., Q. M. (1995). An investigation into the rheological, dielectric and mucoadhesive properties of poly (acrylic acid) gel systems. J. Control. Release, 37, 59-68.
    • (1995) J. Control. Release , vol.37 , pp. 59-68
    • Tamburic, S.1    Craig, D.Q.M.2
  • 49
    • 33846255450 scopus 로고    scopus 로고
    • Detection of Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella intermedia, and Prevotella nigrescens in chronic endodontic infection
    • Tomazinho, L. F., & Avila-Campos, M. J. (2007). Detection of Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella intermedia, and Prevotella nigrescens in chronic endodontic infection. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod., 103(2), 285-288.
    • (2007) Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod , vol.103 , Issue.2 , pp. 285-288
    • Tomazinho, L.F.1    Avila-Campos, M.J.2
  • 50
    • 22444439616 scopus 로고    scopus 로고
    • Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in The Netherlands and Spain
    • Van Winkelhoff, A. J., Herrera, D., Oteo, A., & Sanz, M. (2005). Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in The Netherlands and Spain. J. Clin. Periodontol., 32(8), 891-892.
    • (2005) J. Clin. Periodontol , vol.32 , Issue.8 , pp. 891-892
    • Van Winkelhoff, A.J.1    Herrera, D.2    Oteo, A.3    Sanz, M.4
  • 51
    • 0033928012 scopus 로고    scopus 로고
    • The effects of sustained release doxycycline on the anaerobic flora and antibiotic-resistant patterns in subgingival plaque and saliva
    • Walker, C. B., Godowski, K. C., Borden, L., Lennon, J., Nango, S., Stone, C., & Garrett, S. (2000). The effects of sustained release doxycycline on the anaerobic flora and antibiotic-resistant patterns in subgingival plaque and saliva. J. Periodontol., 71, 768-774.
    • (2000) J. Periodontol , vol.71 , pp. 768-774
    • Walker, C.B.1    Godowski, K.C.2    Borden, L.3    Lennon, J.4    Nango, S.5    Stone, C.6    Garrett, S.7
  • 52
    • 0035195302 scopus 로고    scopus 로고
    • Treatment of periodontitis by local administration of minocycline microspheres: A controlled trial
    • Williams, R. C., Paquette, D. W., Offenbacher, S. et al. (2001). Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J. Periodontol., 72, 1535-1544.
    • (2001) J. Periodontol , vol.72 , pp. 1535-1544
    • Williams, R.C.1    Paquette, D.W.2    Offenbacher, S.3
  • 53
    • 0028431621 scopus 로고
    • Bacteria as risk marker for periodontitis
    • Wolff, L, Dahlen, G., & Aeppli, D. (1994). Bacteria as risk marker for periodontitis. J. Periodontol., 64, 498-510.
    • (1994) J. Periodontol , vol.64 , pp. 498-510
    • Wolff, L.1    Dahlen, G.2    Aeppli, D.3
  • 54
    • 0022600807 scopus 로고
    • Diffusion model for studying the drug release from semisolid dosage forms. Part 1. Methodology using agar gel as diffusion medium
    • Won-Jun, H., & Bayoumi, S. M. (1986). Diffusion model for studying the drug release from semisolid dosage forms. Part 1. Methodology using agar gel as diffusion medium. Drug. Dev. Ind .Pharm., 12(6), 899-914.
    • (1986) Drug. Dev. Ind .Pharm , vol.12 , Issue.6 , pp. 899-914
    • Won-Jun, H.1    Bayoumi, S.M.2
  • 55
    • 0035845756 scopus 로고    scopus 로고
    • Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium
    • Yong., C. H., Choi, J. S., Quan, Q. Z., Rhee, J. D., Kim, C. K., Lim, S. J., Kim, K. M., Oh, P. S., & Choi, H. G. (2001). Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium. Int. J. Pharm., 226, 195-205.
    • (2001) Int. J. Pharm , vol.226 , pp. 195-205
    • Yong, C.H.1    Choi, J.S.2    Quan, Q.Z.3    Rhee, J.D.4    Kim, C.K.5    Lim, S.J.6    Kim, K.M.7    Oh, P.S.8    Choi, H.G.9


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