Selective breeding for intravenous drug self-administration in rats: A pilot study

Behavioural Pharmacology

Volumn 19, Issue 8, 2008, Pages 751-764

  He, Shuangteng ^a   Yang, Yungao ^a   Mathur, Deepan ^a   Grasing, Kenneth ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cocaine; Drug; Morphine; Rat; Reinforcement (psychology); Selection (genetics); Self administration

Indexed keywords

COCAINE; MORPHINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREEDING LINE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; DRUG SELF ADMINISTRATION; FEMALE; FOUNDER EFFECT; GENETIC SELECTION; LOW DRUG DOSE; MALE; NONHUMAN; OUTBRED STRAIN; PILOT STUDY; RAT; REINFORCEMENT; SCORING SYSTEM; SUBSTANCE ABUSE; WISTAR RAT;

ANESTHETICS, LOCAL; ANIMALS; BEHAVIOR, ANIMAL; BREEDING; COCAINE; CONDITIONING, OPERANT; INFUSIONS, INTRAVENOUS; PILOT PROJECTS; RATS; RATS, WISTAR; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION; SUBSTANCE ABUSE, INTRAVENOUS;

EID: 57149145799     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32831c3aec     Document Type: Article

References (36)

1. Allan AM, Galindo R, Chynoweth J, Engel SR, Savage DD (2001). Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor. Psychopharmacology 158:18-27.
2. Brush FR, Driscoll P (2002). Selective breeding program with rats: introduction. Behav Genet 32:275-276.
3. Cadoni C, Di Chiara G (2007). Differences in dopamine responsiveness to drugs of abuse in the nucleus accumbens shell and core of Lewis and Fischer 344 rats. J Neurochem 103:487-499.
4. Caine SB, Lintz R, Koob GF (1993). Intravenous drug self-administration techniques in animals. In: Sahgal A, editor. Behavioral Neuroscience: a practical approach. Oxford: Oxford University Press, pp. 117-143.
5. Carlson KR, Perez L (1997). Ethanol and cocaine intake by rats selectively bred for oral opioid acceptance. Pharmacol Biochem Behav 57:309-313.
6. Comings DE, Blum K (2000). Reward deficiency syndrome: genetic aspects of behavioral disorders. Prog Brain Res 126:325-341.
7. Crabbe JC, Phillips TJ (1993). Selective breeding for alcohol withdrawal severity. Behav Genet 23:171-177.
8. De Vry J, Donselaar I, Van Ree JM (1989). Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol. J Pharmacol Exp Ther 251:735-740.
9. Faraone SV, Adamson JJ, Wilens TE, Monuteaux MC, Biederman J (2008). Familial transmission of derived phenotypes for molecular genetic studies of substance use disorders. Drug Alcohol Depend 92:100-107.
10. Flores G, Wood GK, Barbeau D, Quirion R, Srivastava LK (1998). Lewis and Fischer rats: a comparison of dopamine transporter and receptors levels. Brain Res 814:34-40.
11. Garland T Jr (2001). Phylogenetic comparison and artificial selection; two approaches in evolutionary physiology. In: Roach RC, editor. Hypoxia: from Genes to Bedside. New York: Kluwer Academic/Plenum Publishers, pp. 107-132.
12. Grahame NJ, Li TK, Lumeng L (1999). Selective breeding for high and low alcohol preference in mice. Behav Genet 29:47-57.
13. Grasing K, Li N, He S, Parrish C, Delich J, Glowa J (2003). A new progressive ratio schedule for support of morphine seff-administration in opiate dependent rats. Psychopharmacology 168:387-396.
14. Grasing K, He S, Yang Y (2008). Dose-related effects of the acetylcholinesterase inhibitor tacrine on cocaine and food self-administration in rats. Psychopharmacology 196:133-142.
15. He S, Grasing K (2004). Chronic opiate treatment enhances both cocaine-reinforced and cocaine-seeking behaviors following opiate withdrawal. Drug Alcohol Depend 75:215-221.
16. He S, Grasing K (2006). L-methamphetamine and selective MAO inhibitors decrease morphine-reinforced and non-reinforced behavior in rats; Insights towards selegiline's mechanism of action. Pharmacol Biochem Behav 85:675-688.
17. Johanson CE, Aigner T (1981). Comparison of the reinforcing properties of cocaine and procaine in rhesus monkeys. Pharmacol Biochem Behav 15:49-53.
18. Kamens HM, Burkhart-Kasch S, McKinnon CS, Li N, Reed C, Phillips TJ (2005). Sensitivity to psychostimulants in mice bred for high and low stimulation to methamphetamine. Genes Brain Behav 4:110-125.
19. Kosten TA, Miserendino MJ, Haile CN, DeCaprio JL, Jatlow PI, Nestler EJ (1997). Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains. Brain Res 778:418-429.
20. Kreek MJ, Bart G, Lilly C, LaForge KS, Nielsen DA (2006). Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol Rev 57:1-26.
21. Le AD, Israel Y, Juzytsch W, Quan B, Harding S (2001). Genetic selection for high and low alcohol consumption in a limited-access paradigm. Alcohol Clin Exp Res 25:1613-1620.
22. Martey RJ, Arros DM, Henricks KK, Marley ME, Miner LL (1998). Sensitivity to cocaine and amphetamine among mice selectively bred for differential cocaine sensitivity. Psychopharmacology (Berl) 140:42-51.
23. Martin S, Manzanares J, Corchero J, Garcia-Lecumberri C, Crespo JA, Fuentes JA, Ambrosio E (1999). Differential basal proenkephalin gene expression in dorsal striatum and nucleus accumbens, and vulnerability to morphine self-administration in Fischer 344 and Lewis rats. Brain Res 821:350-365.
24. Mylecharane EJ (1996). Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies. Behav Brain Res 73:1-5.
25. Palmer AA, Verbitsky M, Suresh R, Kamens HM, Reed CL, U N, et al. (2005). Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome 16:291-305.
26. Pontieri FE, Tanda G, Di Chiara G (1995). Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the 'shell' as compared with the 'core' of the rat nucleus accumbens. Proc Natl Acad Sci U S A 92:12304-12308.
27. Rodd ZA, Gryszowka VE, Toalston JE, Oster SM, Ji D, Bell RL, McBride WJ (2007). The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons. J Pharmecol Exp Ther 321:1003-1012.
28. Sanchie-Segura C, Spanagel R (2006). Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol 11:2-38.
29. Shen EH, Harland RD, Crabbe JC, Phillips TJ (1095). Bidirectional selective breeding for ethanol effects on locomotor activity: characterization of FAST and SLOW mice through selection generation 35. Alcohol Clin Exp Res 19:1234-1245.
30. Sizemore GM, Gaspard TM, Kim SA, Walker LE, Vrana SL, Dworkin SI (1907). Dose-effect functions for cocaine self-administration: effects of schedule and dosing procedure. Pharmacol Biochem Behav 57:523-531.
31. Smoten A, Marks MJ, DeFries JC, Hendereon ND (1994). Individual differences in sensitivity to nicotine in mice: response to six generations of selective breeding. Pharmacol Biochem Bahav 49:631-540.
32. Stead JD, Clinton S, Neal C, Schneider J, Jama A, Miller S, et al. (2006). Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors. Behav Genet 36:597-712.
33. Strecker RE, Eberle WF, Ashby CR Jr (1995). Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes. Life Sci 56:L135-L141.
34. Tsuang MT, Bar JL, Harley RM, Lyons MJ (2001). The Harvard Twin Study of Substance Abuse: what we have learned. Harv Rev Psychiatry 9:267-279.
35. Weeks JR, Coffins RJ (1979). Dose and physical dependence as factors in the self-administration of morphine by rats. Paychopharmacology 85:171-177.
36. Will CC, Aird F, Redei EE (2003). Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antideprassants. Mol Psychiatry 8:925-932.