Studies on formulation development of mucoadhesive sustained release itraconazole tablet using response surface methodology

AAPS PharmSciTech

Volumn 9, Issue 3, 2008, Pages 998-1005

  Madgulkar, Ashwini ^a   Kadam, Shivajirao ^a   Pokharkar, Varsha ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Factorial design; Itraconazole; Mucoadhesion; Optimization; Response surface methodology

Indexed keywords

CARBOMER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; ITRACONAZOLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG RETENTION; DRUG SOLUBILITY; FEMALE; HYDROPHILICITY; IN VITRO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PROCESS OPTIMIZATION; RABBIT; SPRAY DRYING; SUSTAINED RELEASE FORMULATION; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADHESIVES; ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; FEMALE; GASTRIC MUCOSA; ITRACONAZOLE; MALE; RABBITS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; SWINE; TABLETS;

EID: 57149132106     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9119-8     Document Type: Article

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