Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane

Molecular and Cellular Neuroscience

Volumn 40, Issue 1, 2009, Pages 14-26

  Samhan Arias, Alejandro K ^a   Garcia Bereguiain, Miguel Angel ^a   Martin Romero, Francisco J ^a   Gutierrez Merino, Carlos ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Caveolin; Cerebellar granule neurons; Cholera toxin B; Cytochrome b5 reductase; Flavoproteins; FRET; Imaging; Lipid rafts; Plasma membrane redox centres; Synaptic plasma membranes

Indexed keywords

ACRIFLAVINE; CYTOCHROME B5 REDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; LIPID RAFT; NERVE CELL MEMBRANE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; SOMATIC CELL; SYNAPSE;

ANIMALS; BRAIN; CATHEPSIN D; CAVEOLIN 2; CELL MEMBRANE; CEREBELLUM; CYTOCHROME-B(5) REDUCTASE; FLAVINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MEMBRANE MICRODOMAINS; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; NEURONS; RATS; RATS, WISTAR; SUPEROXIDES;

RATTUS;

EID: 57149125691     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2008.08.013     Document Type: Article

References (51)

1. 5 reductase are now consistent. Biochemistry 40 (2001) 13574-13582
2. 5 reductase. J.Biol.Chem. 257 (1982) 13854-13861
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
4. Brenman J.E., and Bredt D.S. Synaptic signaling by nitric oxide. Curr. Opin. Neurobiol. 7 (1997) 374-378
5. Chatenay-Rivauday C., Cakar Z.P., Jenö P., Kuzmenko E.S., and Fiedler K. Caveolae: biochemical analysis. Mol. Biol. Rep. 31 (2004) 67-84
6. 5 reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands. Arch. Biochem. Biophys. 400 (2002) 63-75
7. Fazekas A.G., and Kokai K. Extraction, purification and separation of tissue flavines for spectrophotometric determination. Methods Enzymol. 18 (1971) 385-398
8. Forthoffer N., Gomez-Diaz C., Bello R.I., Buron M.I., Martin S.F., Rodriguez-Aguilera J.C., Navas P., and Villalba J.M. A novel plasma membrane quinone reductase and NAD(P)H: quinone oxidoreductase 1 are upregulated by serum withdrawal in human promyelocytic HL-60 cells. J. Bioenerg. Biomembranes 34 (2002) 209-219
9. 2+)-ATPase of rat brain synaptosomes. J. Neurochem. 47 (1986) 668-672
10. 2+)-ATPase activity of synaptosomal plasma membrane by the local anesthetics dibucaine and lidocaine. J. Neurochem. 54 (1990) 1238-1246
11. Gill D.L., Chueh S.H., Noel M.W., and Ueda T. Orientation of synaptic plasma membrane vesicles containing calcium pump and sodium-calcium exchange activities. Biochim. Biophys. Acta 856 (1986) 165-173
12. 2+)-ATPase. Biochim. Biophys. Acta, Biomembr. 897 (1987) 207-216
13. - pulses. Free Radic. Biol. Med. 32 (2002) 46-55
14. 2+ channels to extracellular oxidative/nitrosative stress in cerebellar granule cells. J. Neurochem. 92 (2005) 973-989
15. Gutiérrez-Merino C., Centeno F., García-Martín E., and Merino J.M. Fluorescence energy transfer as a tool to locate functional sites in membrane proteins. Biochem. Soc. Trans. 22 (1994) 784-788
16. Gutiérrez-Merino C., Bonini de Romanelli I.C., Pietrasanta L.I., and Barrantes F.J. Preferential distribution of the fluorescent phospholipid probes NBD-phosphatidylcholine and rhodamine-phosphatidylethanolamine in the exofacial leaflet of acetylcholine receptor-rich membranes from Torpedo marmorata. Biochemistry 34 (1995) 4846-4855
17. 5 and studies on their mechanism of function. Arch. Biochem. Biophys. 312 (1994) 554-565
18. Hyun D.-H., Emerson S.S., Jo D.-G., Mattson M.P., and de Cabo R. Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 19908-19912
19. Hyun D.-H., Hunt N.D., Emerson S.S., Hernandez J.O., Mattson M.P., and de Cabo R. Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria. J. Neurochem. 100 (2007) 1364-1374
20. Janes P.W., Ley S.C., and Magee A.I. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J. Cell Biol. 147 (1999) 447-461
21. Kim C., Crane F.L., Faulk W.P., and Morré D.J. Purification and characterization of a doxorubicin-inhibited NADH-quinone (NADH-ferricyanide) reductase from rat liver plasma membrane. J. Biol. Chem. 277 (2002) 16441-16447
22. 5 reductase in catalysis and control of the rate-limiting step in electron transfer. J. Biol. Chem. 278 (2003) 3580-3589
23. Koziol J. Fluorometric analysis of riboflavin and its coenzymes. Methods Enzymol. 18 (1971) 253-285
24. Lakowicz J.R. Principles of Fluorescence Spectroscopy (1983), Plenum Press, New York
25. Martin-Romero F.J., Santiago-Josefat B., Correa-Bordes J., Gutierrez-Merino C., and Fernandez-Salguero P. Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition. J. Mol. Neurosci. 15 (2000) 155-165
26. Martin-Romero F.J., Gutierrez-Martin Y., Henao F., and Gutierrez-Merino C. The NADH oxidase activity of the plasma membrane of synaptosomes is a major source of superoxide anion and is inhibited by peroxynitrite. J. Neurochem. 82 (2002) 604-614
27. Martin-Romero F.J., Garcia-Martin E., and Gutierrez-Merino C. Inhibition of the oxidative stress produced by plasma membrane NADH oxidase delays low-potassium induced apoptosis of cerebellar granule cells. J. Neurochem. 82 (2002) 705-715
28. Martin-Romero F.J., Samhan-Arias A.K., Garcia-Bereguiain M.A., and Gutierrez-Merino C. Molecular biology of mammalian AFR reductases. Recent Res. Devel. Mol. Biol. 2 (2004) 29-52
29. May J.M. Is ascorbic acid an antioxidant for the plasma membrane?. FASEB J. 13 (1999) 995-1006
30. 5 reductase. Methods Enzymol. 52 (1978) 102-108
31. Morré D.M., Lenaz G., and Morré D.J. Surface oxidase and oxidative stress propagation in aging. J. Exp. Biol. 203 (2000) 1513-1521
32. 5 reductase from pig liver at 2.4 A resolution. Biochemistry 34 (1995) 2763-2767
33. O'Connell K.M.M., Martens J.R., and Tamkun M.M. Localization of ion channels to lipid raft domains within the cardiovascular system. Trends Cardiovasc. Med. 14 (2004) 37-42
34. 5 reductase. Proc. Natl. Acad. Sci. U. S. A 85 (1988) 7246-7250
35. Pietta P., Calatroni A., and Rava A. Hydrolysis of riboflavin nucleotides in plasma monitored by high-performance liquid chromatography. J. Chromatogr. 229 (1982) 445-449
36. 5 toxin family. Biochemistry 35 (1996) 16069-16076
37. Samhan-Arias A.K., Martin-Romero F.J., and Gutierrez-Merino C. Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis. Free Radic. Biol. Med. 37 (2004) 48-61
38. Samhan-Arias A., Garcia-Bereguiain M.A., Martin-Romero F.J., and Gutierrez-Merino C. Regionalization of plasma membrane-bound flavoproteins of cerebellar granule cells in culture by fluorescence energy transfer imaging. J. Fluoresc. 16 (2006) 393-401
39. 5 reductase forms a large network of redox centres that co-localizes with cholera toxin B binding sites in cerebellar granule neurons in culture. Free Radic. Res. 41 Suppl.1 (2007) S52
40. Samhan-Arias A.K., Duarte R.O., Martin-Romero F.J., Moura J.J.G., and Gutierrez-Merino C. Reduction of ascorbate free radical by the plasma membrane of synaptic terminals from rat brain. Arch. Biochem. Biophys. 469 (2008) 243-254
41. Singer T.P., Salach J., Hemmerich P., and Ehrenberg A. Flavin peptides. Methods Enzymol. 18 (1971) 416-427
42. 5 aporeductase during reversible denaturation. J. Biol. Chem. 242 (1967) 4630-4636
43. Valencia A., and Moran J. Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons. J. Neurosci. Res. 64 (2001) 284-297
44. Villalba J.M., Canalejo A., Rodriguez-Aguilera J.C., Buron M.I., Morré D.J., and Navas P. NADH-ascorbate free radical and -ferricyanide reductase activities represent different levels of plasma membrane electron transport. J. Bioenerg. Biomembranes 25 (1993) 411-417
45. Villalba J.M., Navarro F., Cordoba F., Serrano A., Arroyo A., Crane F.L., and Navas P. Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 4887-4891
46. 5 reductase on the antioxidant function of coenzyme Q in the plasma membrane. Mol. Aspects Med. 18Suppl (1997) S7-S13
47. Williams Jr. C.H. Flavin-containing dehydrogenases. In: Boyer P.D. (Ed). The Enzymes, vol. XIII (1976), Academic Press, New York 173-189
48. Wright M.V., and Kuhn T.B. CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability. J. Neurochem. 83 (2002) 655-664
49. Yong Y., and Dreyer J.L. Distribution of six transplasma membrane NADH-dehydrogenases in rat brain tissue. Brain Res. Dev. Brain Res. 89 (1995) 235-252
50. Yong Y., and Dreyer J.L. Developmental changes in the localization of the transplasma membrane NADH-dehydrogenases in the rat brain. Brain Res. Dev. Brain Res. 89 (1995) 253-263
51. Zurbriggen R., and Dreyer J.L. The plasma membrane NADH-diaphorase is active during selective phases of the cell cycle in mouse neuroblastoma cell line NB41A3. Its relation to cell growth and differentiation. Biochim. Biophys. Acta 1312 (1996) 215-222