Role of cytochrome b5, reductase on the antioxidant function of coenzyme Q in the plasma membrane

Molecular Aspects of Medicine

Volumn 18, Issue SUPPL., 1997, Pages 7-13

  Villalba, J M ^a   Navarro, F ^a   Gomez Diaz C ^a   Arroyo, A ^a   Bello, R I ^a   Navas, P ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Apoptosis; Ascorbate; Coenzyme Q; Cytochrome b5 reductase; Lipid peroxidation

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CYTOCHROME B5 REDUCTASE; FREE RADICAL; LIPOSOME; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UBIQUINONE; L ASCORBATE CYTOCHROME B5 REDUCTASE; L-ASCORBATE--CYTOCHROME-B5 REDUCTASE; MEMBRANE PROTEIN; MONODEHYDROASCORBATE REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME PURIFICATION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER CELL MEMBRANE; NONHUMAN; OXIDATIVE STRESS; REDUCTION; ANIMAL; CELL MEMBRANE; LIVER; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REVIEW;

ANIMALIA;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASCORBIC ACID; CELL MEMBRANE; HUMANS; LIPID PEROXIDATION; LIPOSOMES; LIVER; MEMBRANE PROTEINS; NAD; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES; PROTO-ONCOGENE PROTEINS C-BCL-2; UBIQUINONE;

EID: 0030629508     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0098-2997(97)00015-0     Document Type: Conference Paper

References (26)

1. Alcaín, F. J., Burón, M. I., Villalba, J. M. and Navas, P. (1991). Ascorbate is regenerated by HL-60 cells through the transplasmalemma redox system. Biochimica Biophysica Acta, 1073, 380-385.
2. Beyer, R. E. (1994). The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q. Journal of Bioenergetics and Biomembranes, 26, 349-358.
3. Burón, M. I., Villalba, J. M. and Navas, P. (1987). NADH-ascorbate free radical reductase of rat liver plasma membranes: kinetics and lectin inhibition. Epithelia, 1, 295-306.
4. Crane, F. L., Löw, H. and Clark, M. G. (1985) Plasma membrane redox enzymes. In: The Enzymes of Biological Membranes, (Martonosi, A. N., ed.), Vol. 4, pp. 465-510. Plenum Press, New York.
5. Frei, B. (1994). Reactive oxygen species and antioxidant vitamins: mechanisms of action. American Journal of Medicine, 97, 5S-13S.
6. Goldman, R., Stoyanovsky, D. A., Tsyrlov, I. B., Grogan, J. and Kagan, V. E. (1993). Reduction of phenoxyl radicals by the purified human NADPH-cytochrome P450 reductase. Free Radicals in Biology and Medicine, 15, 542
7. 10 reductase in plasma membrane. Journal of Bioenergetics and Biomembranes. (in press).
8. Hockenbery, D. M., Oltvai, Z. N., Yin, X.-M-., Milliman, C. L. and Korsmeyer, S. J. (1993). Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell, 75, 241-251.
9. Ishizaki, Y., Cheng, L., Mudge, A. W. and Raff, M. C. (1995). Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells. Molecular Biology of the Cell, 6, 1443-1458.
10. Kagan, V. E., Nohl, H. and Quinn, P. J. (1996) Coenzyme Q: its role in scavenging and generation of radicals in membranes. In Handbook of Antioxidants (E. Cadenas and L. Packer, eds.), pp. 157-201. Marcel Dekker, New York.
11. Kant, J. A. and Steck, T. L. (1972). Cation-impermeable inside-out and right-side-out vesicles from human erythrocyte membranes. Nature, 240, 26-28.
12. Kobayashi, K., Harada, Y. and Hayashi, K. (1991). Kinetic behavior of the monodedydroascorbate radical studied by pulse radiolysis. Biochemistry, 30, 8310-8315.
13. Minetti, M., Forte, T., Sotiani, M., Quaresima, V., Menditto, A. and Ferrari, M. (1992). Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. Biochemistry Journal, 282, 459-465.
14. Nakamura, M. and Hayashi, T. (1994). One-and two-electron reduction of quinones by rat liver subcellular fractions. Journal of Biochemistry, 115, 1141-1147.
15. Navarro, F., Villalba, J. M., Crane, F. L., MacKellar, W. C. and Navas, P. (1995). A phospholipid-dependent NADH-coenzyme Q reductase from liver plasma membrane. Biochemistry and Biophysics Research Communication, 212, 138-143.
16. Navas, P. and Burón, M. I. (1990) Role of pyridine nucleotides in the control of cell growth. In Oxidoreduction at the Plasma Membrane: Relation to Growth and Transport (F. L. Crane, D. J. Morré and H. E. Löw, eds), Vol. I, pp. 225-236. CRC Press, Boca Raton
17. Pethig, R., Gascoyne, P. R.C., McLaughlin, J. A. and Szent-Györgyi, A. (1985). Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxysemiquinone free radicals in Ehrlich ascites tunor cells. Proceedings of the National Academy of Science, 82, 1439-1442.
18. 5 to plasma membranes of rat liver. Its implication for membrane specificity and biogenesis. Biochimica Biophysica Acta, 597, 564-576.
19. Rodríguez-Aguilera, J. C. and Navas, P. (1994). Extracellular ascorbate stabilization: enzymatic or chemical process?. Journal of Bioenergetics and Biomembranes, 26, 379-384.
20. Rose, R. C. and Bode, A. M. (1993). Biology of free radical scavengers: an evaluation of ascorbate. FASEB Journal, 7, 1135-1142.
21. Schultz, J. R., Ellerby, L. M., Gralla, E. B., Valentine, J. S. and Clarke, C. F. (1996). Autoxidation of ubiquinol-6 is independent of superoxide dismutase. Biochemistry, 35, 6595-6603.
22. 5 reductase gene results in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with type II hereditary methemoglobinemia. American Journal of Human Genetics, 57, 302-310.
23. Slater, A. F. G., Stefan, C., Nobel, Y., van den Dobbelsteen, D. and Orrenius, S. (1996). Intracellular redox changes during apoptosis. Cell Death and Differentiation, 3, 57-62.
24. Sun, I. L., Sun, E. E., Crane, F. L., Morré, D. J., Lindgren, A. and Löw, H. (1992). Requirement for coenzyme Q in plasma membrane electron transport. Proceedings of the National Academy of Science USA, 89, 11126-11130.
25. Vaux, D. L. and Strasser, A. (1996). The molecular biology of apoptosis. Proceedings of the National Academy of Science USA, 93, 2239-2244.
26. Villalba, J. M., Navarro, F., Córdoba, F., Serrano, A., Arroyo, A., Crane, F. L. and Navas, P. (1995). Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma membrane electron transport. Proceedings of the National Academy of Science USA, 92, 4887-4891.