메뉴 건너뛰기




Volumn 95, Issue 1, 2009, Pages 55-64

Cloning of the Rhizomucor miehe 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene and its heterologous expression in Mucor circinelloides

Author keywords

Carotenoid; HMG coenzyme A reductase; Statin; Sterol

Indexed keywords

AMINO ACID; CAROTENOID; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN; STEROL; FUNGAL PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH);

EID: 57149102877     PISSN: 00036072     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10482-008-9287-2     Document Type: Article
Times cited : (15)

References (38)
  • 3
    • 0026632637 scopus 로고
    • Independence of the carotene and sterol pathways of Phycomyces
    • doi: 10.1016/0014-5793(92)81002-4
    • Bejarano ER, Cerda-Olmedo E (1992) Independence of the carotene and sterol pathways of Phycomyces. FEBS J 306:209-212. doi: 10.1016/ 0014-5793(92)81002-4
    • (1992) FEBS J , vol.306 , pp. 209-212
    • Bejarano, E.R.1    Cerda-Olmedo, E.2
  • 4
    • 0026696823 scopus 로고
    • Cloning and sequence analysis of the Mucor circinelloides pyrG gene encoding orotidine-5′-monophosphate decarboxylase: Use of pyrG for homologous transformation
    • doi: 10.1016/0378-1119(92)90629-4
    • Benito EP, Díaz-Mínguez JM, Itturiaga EA, Campuzano EA, Eslava AP (1992) Cloning and sequence analysis of the Mucor circinelloides pyrG gene encoding orotidine-5′-monophosphate decarboxylase: Use of pyrG for homologous transformation. Gene 116:59-67. doi: 10.1016/0378-1119(92)90629-4
    • (1992) Gene , vol.116 , pp. 59-67
    • Benito, E.P.1    Díaz-Mínguez, J.M.2    Itturiaga, E.A.3    Campuzano, E.A.4    Eslava, A.P.5
  • 5
    • 0028256429 scopus 로고
    • Sequence comparison of a segment of the gene for 3-hydroxy-methylglutaryl-coenzyme A reductase in zygomycetes
    • doi: 10.1111/j.1432-1033.1994.tb18637.x
    • Burmester A, Czempinski K (1994) Sequence comparison of a segment of the gene for 3-hydroxy-methylglutaryl-coenzyme A reductase in zygomycetes. Eur J Biochem 220:403-408. doi: 10.1111/j.1432-1033.1994.tb18637.x
    • (1994) Eur J Biochem , vol.220 , pp. 403-408
    • Burmester, A.1    Czempinski, K.2
  • 6
    • 29944441034 scopus 로고    scopus 로고
    • Lovastatin has significant activity against zygomycetes and interacts synergistically with voriconazole
    • doi: 10.1128/AAC.50.1.96-103.2006
    • Chamilos G, Lewis RE, Kontoyiannis DP (2006) Lovastatin has significant activity against zygomycetes and interacts synergistically with voriconazole. Antimicrob Agents Chemother 50:96-103. doi: 10.1128/ AAC.50.1.96-103.2006
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 96-103
    • Chamilos, G.1    Lewis, R.E.2    Kontoyiannis, D.P.3
  • 7
    • 0000562132 scopus 로고
    • Cloning a segment of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Phycomyces blakesleeanus and Gibberella fujikuroi by the polymerase chain reaction
    • doi: 10.1016/0147-5975(92)90024-L
    • Corrochano LM, Avalos J (1992) Cloning a segment of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Phycomyces blakesleeanus and Gibberella fujikuroi by the polymerase chain reaction. Exp Mycol 16:167-171. doi: 10.1016/0147-5975(92)90024-L
    • (1992) Exp Mycol , vol.16 , pp. 167-171
    • Corrochano, L.M.1    Avalos, J.2
  • 8
    • 14644430471 scopus 로고    scopus 로고
    • PROBCONS: Probabilistic consistency-based multiple sequence alignment
    • doi: 10.1101/gr.2821705
    • Do CB, Mahabhashyam MS, Brudno M, Batzoglou S (2005) PROBCONS: probabilistic consistency-based multiple sequence alignment. Genome Res 15:330-340. doi: 10.1101/gr.2821705
    • (2005) Genome Res , vol.15 , pp. 330-340
    • Do, C.B.1    Mahabhashyam, M.S.2    Brudno, M.3    Batzoglou, S.4
  • 9
    • 39849102805 scopus 로고    scopus 로고
    • Regulation of sterol synthesis in Eukaryotes
    • doi: 10.1146/annurev.genet.41.110306.130315
    • Espenshade PJ, Hughes AL (2007) Regulation of sterol synthesis in Eukaryotes. Annu Rev Genet 41:401-427. doi: 10.1146/ annurev.genet.41.110306.130315
    • (2007) Annu Rev Genet , vol.41 , pp. 401-427
    • Espenshade, P.J.1    Hughes, A.L.2
  • 10
    • 0025082117 scopus 로고
    • Nit-2, the major positive-acting nitrogen regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein
    • doi: 10.1073/pnas.87.14.5331
    • Fu YH, Marzluf GA (1990) Nit-2, the major positive-acting nitrogen regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein. Proc Natl Acad Sci USA 87:5331-5335. doi: 10.1073/ pnas.87.14.5331
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5331-5335
    • Fu, Y.H.1    Marzluf, G.A.2
  • 11
    • 34247140262 scopus 로고    scopus 로고
    • Interactions between statins and Penicillium chrysogenum antifungal protein (PAF) to inhibit the germination of sporangiospores of different sensitive zygomycetes
    • doi: 10.1111/j.1574-6968.2007.00661.x
    • Galgóczy L, Papp T, Leiter É, Pócsi I, Válgvölgyi CS (2007) Interactions between statins and Penicillium chrysogenum antifungal protein (PAF) to inhibit the germination of sporangiospores of different sensitive zygomycetes. FEMS Microbiol Lett 270:109-115. doi: 10.1111/j.1574-6968.2007.00661.x
    • (2007) FEMS Microbiol Lett , vol.270 , pp. 109-115
    • Galgóczy, L.1    Papp, T.2    Leiter, É.3    Pócsi, I.4    Válgvölgyi, C.S.5
  • 12
    • 0242578620 scopus 로고    scopus 로고
    • A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood
    • doi: 10.1080/10635150390235520
    • Guindon S, Gascuel O (2003) A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 52:696-704. doi: 10.1080/10635150390235520
    • (2003) Syst Biol , vol.52 , pp. 696-704
    • Guindon, S.1    Gascuel, O.2
  • 13
    • 23144433822 scopus 로고    scopus 로고
    • PHYML online - A web server for fast maximum likelihood-based phylogenetic inference
    • doi: 10.1093/nar/gki352
    • Guindon S, Lethiec F, Duroux P, Gascuel O (2005) PHYML online - a web server for fast maximum likelihood-based phylogenetic inference. Nucleic Acids Res 33:W557-W559. doi: 10.1093/nar/gki352
    • (2005) Nucleic Acids Res , vol.33
    • Guindon, S.1    Lethiec, F.2    Duroux, P.3    Gascuel, O.4
  • 14
    • 0002949582 scopus 로고
    • The structure and organization of nuclear genes of filamentous fungi
    • In: Kinghorn JR (ed) IRL, Oxford
    • Gurr SJ, Unkles SE, Kinghorn JR (1987) The structure and organization of nuclear genes of filamentous fungi. In: Kinghorn JR (ed) Gene structure in eukaryotic microbes. IRL, Oxford, pp 93-139
    • (1987) Gene Structure in Eukaryotic Microbes , pp. 93-139
    • Gurr, S.J.1    Unkles, S.E.2    Kinghorn, J.R.3
  • 15
    • 0000207681 scopus 로고
    • TMbase - A database of membrane spanning proteins segments
    • Hofmann K, Stoffel W (1993) TMbase - a database of membrane spanning proteins segments. Biol Chem Hoppe Seyler 374:166-172
    • (1993) Biol Chem Hoppe Seyler , vol.374 , pp. 166-172
    • Hofmann, K.1    Stoffel, W.2
  • 16
    • 0034161543 scopus 로고    scopus 로고
    • Crystal structure of the catalytic portion of human HMG-CoA reductase: Insights into regulation of activity and catalysis
    • doi: 10.1093/emboj/19.5.819
    • Istvan ES, Palnitkar M, Buchanan SK, Deisenhofer J (2000) Crystal structure of the catalytic portion of human HMG-CoA reductase: Insights into regulation of activity and catalysis. EMBO J 19:819-830. doi: 10.1093/emboj/19.5.819
    • (2000) EMBO J , vol.19 , pp. 819-830
    • Istvan, E.S.1    Palnitkar, M.2    Buchanan, S.K.3    Deisenhofer, J.4
  • 17
    • 0026691182 scopus 로고
    • The rapid generation of mutation data matrices from protein sequences
    • Jones DT, Taylor WR, Thornton JM (1992) The rapid generation of mutation data matrices from protein sequences. CABIOS 8:275-282
    • (1992) CABIOS , vol.8 , pp. 275-282
    • Jones, D.T.1    Taylor, W.R.2    Thornton, J.M.3
  • 18
    • 1842788119 scopus 로고    scopus 로고
    • Simvastatin induces apoptosis of eppstein-barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas
    • doi: 10.1073/pnas.0305149101
    • Katano H, Pesnicak L, Cohen JI (2004) Simvastatin induces apoptosis of eppstein-barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas. Proc Natl Acad Sci USA 101:4960-4965. doi: 10.1073/pnas.0305149101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4960-4965
    • Katano, H.1    Pesnicak, L.2    Cohen, J.I.3
  • 19
    • 0035092874 scopus 로고    scopus 로고
    • Phase II study of high dose lovastatin in patients with advanced gastric adenocarcinoma
    • doi: 10.1023/A:1006481423298
    • Kim SW, Kim MM, Choi HJ, Yoon SS, Lee MH, Park K, Park CH, Kang WK (2001) Phase II study of high dose lovastatin in patients with advanced gastric adenocarcinoma. Invest New Drugs 19:81-83. doi: 10.1023/ A:1006481423298
    • (2001) Invest New Drugs , vol.19 , pp. 81-83
    • Kim, S.W.1    Kim, M.M.2    Choi, H.J.3    Yoon, S.S.4    Lee, M.H.5    Park, K.6    Park, C.H.7    Kang, W.K.8
  • 20
    • 0023930331 scopus 로고
    • Transformation of Penicillium chrysogenum using dominant selection markers and expression of an Escherichia coli lacZ fusion gene
    • doi: 10.1016/0378-1119(88)90586-0
    • Kolar M, Punt PJ, Van den Hondel CA, Schwab H (1988) Transformation of Penicillium chrysogenum using dominant selection markers and expression of an Escherichia coli lacZ fusion gene. Gene 62:127-134. doi: 10.1016/ 0378-1119(88)90586-0
    • (1988) Gene , vol.62 , pp. 127-134
    • Kolar, M.1    Punt, P.J.2    Van den Hondel, C.A.3    Schwab, H.4
  • 21
    • 0025220463 scopus 로고
    • The regulatory gene are a mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger
    • Kudla B, Caddick MX, Langdon T, Martinez-Rossi NM, Bennett CF, Sibley S, Davies RW, Arst HN (1990) The regulatory gene are a mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger. EMBO J 9:1355-1364
    • (1990) EMBO J , vol.9 , pp. 1355-1364
    • Kudla, B.1    Caddick, M.X.2    Langdon, T.3    Martinez-Rossi, N.M.4    Bennett, C.F.5    Sibley, S.6    Davies, R.W.7    Arst, H.N.8
  • 22
    • 0036534286 scopus 로고    scopus 로고
    • The sterol-sensing domain: Multiple families, a unique role?
    • doi: 10.1016/S0168-9525(02)02640-9
    • Kuwabara PE, Labouesse M (2002) The sterol-sensing domain: Multiple families, a unique role? Trends Genet 18:193-201. doi: 10.1016/ S0168-9525(02)02640-9
    • (2002) Trends Genet , vol.18 , pp. 193-201
    • Kuwabara, P.E.1    Labouesse, M.2
  • 23
    • 33751415908 scopus 로고    scopus 로고
    • Relationships among the biosynthesis of ubiquinone, carotene, sterols, and triacylglycerols in zygomycetes
    • doi: 10.1007/s00203-006-0166-9
    • Kuzina V, Domenech C, Cerdá-Olmedo E (2006) Relationships among the biosynthesis of ubiquinone, carotene, sterols, and triacylglycerols in zygomycetes. Arch Microbiol 186:485-493. doi: 10.1007/ s00203-006-0166-9
    • (2006) Arch Microbiol , vol.186 , pp. 485-493
    • Kuzina, V.1    Domenech, C.2    Cerdá-Olmedo, E.3
  • 24
    • 8644276266 scopus 로고    scopus 로고
    • Differentiation of Rhizomucor species on the basis of their different sensitivities to lovastatin
    • doi: 10.1128/JCM.42.11.5400-5402.2004
    • Lukács GY, Papp T, Nyilasi I, Nagy E, Vágvölgyi Cs (2004) Differentiation of Rhizomucor species on the basis of their different sensitivities to lovastatin. J Clin Microbiol 42:5400-5402. doi: 10.1128/JCM.42.11.5400-5402.2004
    • (2004) J Clin Microbiol , vol.42 , pp. 5400-5402
    • Lukács, G.Y.1    Papp, T.2    Nyilasi, I.3    Nagy, E.4    Vágvölgyi, C.S.5
  • 25
    • 33747077887 scopus 로고    scopus 로고
    • Growth inhibition of Candida species and Aspergillus fumigatus by statins
    • doi: 10.1111/j.1574-6968.2006.00370.x
    • Macreadie IG, Johnson G, Schlosser T, Macreadie PI (2006) Growth inhibition of Candida species and Aspergillus fumigatus by statins. FEMS Microbiol Lett 262:9-13. doi: 10.1111/j.1574-6968.2006.00370.x
    • (2006) FEMS Microbiol Lett , vol.262 , pp. 9-13
    • Macreadie, I.G.1    Johnson, G.2    Schlosser, T.3    Macreadie, P.I.4
  • 26
    • 0028238115 scopus 로고
    • Electrophoretic karyotype of Mucor circinelloides
    • doi: 10.1007/BF00326303
    • Nagy Á, Vágvölgyi Cs, Balla É, Ferenczy L (1994) Electrophoretic karyotype of Mucor circinelloides. Curr Genet 26:45-48. doi: 10.1007/BF00326303
    • (1994) Curr Genet , vol.26 , pp. 45-48
    • Nagy, Á.1    Vágvölgyi, C.S.2    Balla, É.3    Ferenczy, L.4
  • 27
    • 0002439624 scopus 로고
    • Microbial proteinases and biotechnology
    • In: Fogarty WM, Kelly CT (eds) Elsevier, London
    • Outtrup H, Boyce COL (1990) Microbial proteinases and biotechnology. In: Fogarty WM, Kelly CT (eds) Microbial enzymes and biotechnology. Elsevier, London, pp 227-254
    • (1990) Microbial Enzymes and Biotechnology , pp. 227-254
    • Outtrup, H.1    Boyce, C.O.L.2
  • 30
    • 0025999293 scopus 로고
    • Ras isoprenilation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells
    • doi: 10.1083/jcb.115.3.795
    • Qiu MS, Pitts AF, Winters TR, Green SH (1991) Ras isoprenilation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells. J Cell Biol 115:795-808. doi: 10.1083/ jcb.115.3.795
    • (1991) J Cell Biol , vol.115 , pp. 795-808
    • Qiu, M.S.1    Pitts, A.F.2    Winters, T.R.3    Green, S.H.4
  • 31
    • 0034040526 scopus 로고    scopus 로고
    • Zygomycetes in human disease
    • doi: 10.1128/CMR.13.2.236-301.2000
    • Ribes JA, Vanover-Sams CL, Baker DJ (2000) Zygomycetes in human disease. Clin Microbiol Rev 13:236-301. doi: 10.1128/CMR.13.2.236-301.2000
    • (2000) Clin Microbiol Rev , vol.13 , pp. 236-301
    • Ribes, J.A.1    Vanover-Sams, C.L.2    Baker, D.J.3
  • 32
    • 0032214453 scopus 로고    scopus 로고
    • Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus
    • doi: 10.1006/fgbi.1998.1093
    • Roze LV, Linz JE (1998) Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus. Fungal Genet Biol 25:119-133. doi: 10.1006/fgbi.1998.1093
    • (1998) Fungal Genet Biol , vol.25 , pp. 119-133
    • Roze, L.V.1    Linz, J.E.2
  • 33
    • 0035678748 scopus 로고    scopus 로고
    • Genes for mevalonate biosynthesis in Phycomyces
    • doi: 10.1007/s004380100565
    • Ruiz-Albert J, Cerdá-Olmedo E, Corrochano LM (2002) Genes for mevalonate biosynthesis in Phycomyces. Mol Genet Genomics 266:768-777. doi: 10.1007/s004380100565
    • (2002) Mol Genet Genomics , vol.266 , pp. 768-777
    • Ruiz-Albert, J.1    Cerdá-Olmedo, E.2    Corrochano, L.M.3
  • 35
    • 0034786532 scopus 로고    scopus 로고
    • The HMMTOP transmembrane topology prediction server
    • doi: 10.1093/bioinformatics/17.9.849
    • Tusnády GE, Simon I (2001) The HMMTOP transmembrane topology prediction server. Bioinformatics 17:849-850. doi: 10.1093/ bioinformatics/17.9.849
    • (2001) Bioinformatics , vol.17 , pp. 849-850
    • Tusnády, G.E.1    Simon, I.2
  • 36
    • 51849181211 scopus 로고
    • High frequency transformation of Mucor with recombinant plasmid DNA
    • doi: 10.1007/BF02907500
    • van Heeswijck R, Roncero MIG (1984) High frequency transformation of Mucor with recombinant plasmid DNA. Carlsberg Res Commun 49:691-702. doi: 10.1007/BF02907500
    • (1984) Carlsberg Res Commun , vol.49 , pp. 691-702
    • van Heeswijck, R.1    Roncero, M.I.G.2
  • 37
    • 4043181283 scopus 로고    scopus 로고
    • Cloning and sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase gene from the zygomycetes fungus Rhizomucor miehei
    • doi: 10.1023/B:ANTO.0000036118.41484.e7
    • Vastag M, Kasza Z, Ács K, Papp T, Schwab H, Cs Vágvölgyi (2004) Cloning and sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase gene from the zygomycetes fungus Rhizomucor miehei. Antonie Van Leeuwenhoek 86:111-119. doi: 10.1023/B:ANTO.0000036118.41484.e7
    • (2004) Antonie Van Leeuwenhoek , vol.86 , pp. 111-119
    • Vastag, M.1    Kasza, Z.2    Ács, K.3    Papp, T.4    Schwab, H.5    Vágvölgyi, C.S.6
  • 38
    • 0031040015 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl-CoA reductase gene of Gibberella fujikuroi: Isolation and characterization
    • doi: 10.1007/s002940050174
    • Woitek S, Unkles SE, Kinghorn JR, Tudzynski B (1997) 3-Hydroxy-3-methylglutaryl-CoA reductase gene of Gibberella fujikuroi: isolation and characterization. Curr Genet 31:38-47. doi: 10.1007/ s002940050174
    • (1997) Curr Genet , vol.31 , pp. 38-47
    • Woitek, S.1    Unkles, S.E.2    Kinghorn, J.R.3    Tudzynski, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.