Distribution of CCR5-Δ32, CCR2-64I, SDF1-3′A, CX3CR1-249I, and CX3CR1-280M in Chinese populations

AIDS Research and Human Retroviruses

Volumn 24, Issue 11, 2008, Pages 1391-1397

  Qian, Yuan ^a   Sun, Hao ^a   Lin, Keqin ^a   Shi, Lei ^a   Shi, Li ^a   Chu, Jiayou ^a  

^a INSTITUTE OF MEDICAL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CX3CR1; STROMAL CELL DERIVED FACTOR 1; CCR2 PROTEIN, HUMAN; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; CHINESE; DISEASE COURSE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; CHINA; GENETICS; GEOGRAPHY;

CHEMOKINE CXCL12; CHINA; GENE FREQUENCY; GEOGRAPHY; HUMANS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, CCR2; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE;

EID: 57049179070     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2008.0048     Document Type: Article

References (40)

1. Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, Lomb DA, Goedert JJ, O'Brien TR, Jacobson LP, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner MW, and O'Brien SJ: Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science 1997;277:959-965.
2. Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, Kang S, Ceradini D, Jin Z, Yazdanbakhsh K, Kunstman K, Erickson D, Dragon E, Landau NR, Phair J, Ho DD,and Koup RA: The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996;2:1240-1243.
3. Dezzutti CS, Guenthner PC, Green TA, Cohen OJ, Spira TJ, and Lal RB: Stromal-derived factor-1 chemokine gene variant is associated with the delay of HIV-1 disease progression in two longitudinal cohorts. Aids 2000;14:894-896.
4. Winkler CA, Hendel H, Carrington M, Smith MW, Nelson GW, O'Brien S J, Phair J, Vlahov D, Jacobson LP, Rappaport J, Vasilescu A, Bertin-Maghit S, An P, Lu W, Andrieu JM, Schachter F, Therwath A, and Zagury JF: Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression. J Acquir Immune Defic Syndr 2004;37:1534-1538.
5. Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, Goedert JJ, Buchbinder SP, Vittinghoff E, Gomperts E, Donfield S, Vlahov D, Kaslow R, Saah A, Rinaldo C, Detels R, and O'Brien SJ: Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996;273:1856-1862.
6. Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, Lee B, Doms RW, Margolick J, Buchbinder S, Goedert JJ, O'Brien TR, Hilgartner MW, Vlahov D, O'Brien SJ, and Carrington M: Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 1998;282:1907-1911.
7. Bleul CC, Farzan M, Choe H, Parolin C, Clark-Lewis I, Sodroski J, and Springer TA: The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382:829-833.
8. Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, Schwartz O, Heard JM, Clark-Lewis I, Legler DF, Loetscher M, Baggiolini M, and Moser B: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996;382:833-835.
9. Winkler C, Modi W, Smith MW, Nelson GW, Wu X, Carrington M, Dean M, Honjo T, Tashiro K, Yabe D, Buchbinder S, Vittinghoff E, Goedert JJ, O'Brien TR, Jacobson LP, Detels R, Donfield S, Willoughby A, Gomperts E, Vlahov D, Phair J, and O'Brien SJ: Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC). Science 1998;279:389-393.
10. Brambilla A, Villa C, Rizzardi G, Veglia F, Ghezzi S, Lazzarin A, Cusini M, Muratori S, Santagostino E, Gringeri A, Louie LG, Sheppard HW, Poli G, Michael NL, Pantaleo G, and Vicenzi E: Shorter survival of SDF1-3′A/ 3′A homozygotes linked to CD4+ T cell decrease in advanced human immunodeficiency virus type 1 infection. J Infect Dis 2000;182:311-315.
11. Meyer L, Magierowska M, Hubert JB, Theodorou I, van Rij R, Prins M, de Roda Husman AM, Coutinho R, and Schuitemaker H: CC-chemokine receptor variants, SDF-1 polymorphism, and disease progression in 720 HIV-infected patients. SEROCO Cohort. Amsterdam Cohort Studies on AIDS. AIDS 1999;13:624-626.
12. Mummidi S, Ahuja SS, Gonzalez E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, and Ahuja SK: Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression. Nat Med 1998;4:786-793.
13. van Rij RP, Broersen S, Goudsmit J, Coutinho RA, and Schuitemaker H: The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection. AIDS 1998;12:F85-90.
14. Faure S, Meyer L, Costagliola D, Vaneensberghe C, Genin E, Autran B, Delfraissy JF, McDermott DH, Murphy PM, Debre P, Theodorou I, and Combadiere C: Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1. Science 2000;287:2274-2277.
15. McDermott DH, Colla JS, Kleeberger CA, Plankey M, Rosenberg PS, Smith ED, Zimmerman PA, Combadiere C, Leitman SF, Kaslow RA, Goedert JJ, Berger EA, O'Brien TR, and Murphy PM: Genetic polymorphism in CX3CR1 and risk of HIV disease. Science 2000;290:2031.
16. Wang FS, Hong WG, Cao Y, Liu MX, Jin L, Hu LP, Wang Z, Feng TJ, Hou J, Zhang B, Shi M, Xu DP, Lei ZY, Wang B, Liu ZD, Ye JJ, Peng L, Qiu Y, and Winkler C: Population survey of CCR5 delta32, CCR5 m303, CCR2b 64I, and SDF1 3′A allele frequencies in indigenous Chinese healthy individuals, and in HIV-1-infected and HIV-1-uninfected individuals in HIV-1 risk groups. J Acquir Immune Defic Syndr 2003;32:124-130.
17. Su B, Jin L, Hu F, Xiao J, Luo J, Lu D, Zhang W, Chu J, Du R, Geng Z, Qiu X, Xue J, Tan J, O'Brien SJ, and Chakraborty R: Distribution of two HIV-1-resistant polymorphisms (SDF1-3′A and CCR2-64I) in East Asian and world populations and its implication in AIDS epidemiology. Am J Hum Genet 1999;65:1047-1053.
18. Gonzalez E, Dhanda R, Bamshad M, Mummidi S, Geevarghese R, Catano G, Anderson SA, Walter EA, Stephan KT, Hammer MF, Mangano A, Sen L, Clark RA, Ahuja SS, Dolan MJ, and Ahuja SK: Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: Impact on the epidemiology of the HIV-1 pandemic. Proc Natl Acad Sci USA 2001;98:5199-5204.
19. Liu Z, Lian Z, and Zhao C: Drug use and HIV/AIDS in China. Drug Alcohol Rev 2006;25:173-175.
20. Deng R, Li J, Sringernyuang L, and Zhang K: Drug abuse, HIV/AIDS and stigmatisation in a Dai community in Yunnan, China. Soc Sci Med 2007;64:1560-1571.
21. Yang X, Derlega VJ, and Luo H: Migration, behaviour change and HIV/STD risks in China. AIDS Care 2007;19:282-288.
22. Struyf F, Thoelen I, Charlier N, Keyaerts E, Van der Donck I, Wuu J, and Van Ranst M: Prevalence of CCR5 and CCR2 HIV-coreceptor gene polymorphisms in Belgium. Hum Hered 2000;50:304-307.
23. Apostolakis S, Baritaki S, Krambovitis E, and Spandidos DA: Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population. J Clin Virol 2005;34:310-314.
24. Su B, Sun G, Lu D, Xiao J, Hu F, Chakraborty R, Deka R, and Jin L: Distribution of three HIV-1 resistance-conferring polymorphisms (SDF1-3′A, CCR2-641, and CCR5-delta32) in global populations. Eur J Hum Genet 2000;8:975-979.
25. Voevodin A, Samilchuk E, and Dashti S: Frequencies of SDF-1 chemokine, CCR-5, and CCR-2 chemokine receptor gene alleles conferring resistance to human immunodeficiency virus type 1 and AIDS in Kuwaitis. J Med Virol 1999;58:54-58.
26. Martinson JJ, Hong L, Karanicolas R, Moore JP, and Kostrikis LG: Global distribution of the CCR2-64I/CCR5-59653T HIV-1 disease-protective haplotype. AIDS 2000;14:483-489.
27. [National sentinel surveillance of HIV infection in China from 1995 to 1998]. Zhonghua Liu Xing Bing Xue Za Zhi 2000;21:7-9.
28. Chu JY, Huang W, Kuang SQ, Wang JM, Xu JJ, Chu ZT, Yang ZQ, Lin KQ, Li P, Wu M, Geng ZC, Tan CC, Du RF, and Jin L: Genetic relationship of populations in China. Proc Natl Acad Sci USA 1998;95:11763-11768.
29. Black ML, Wise CA, Wang W, and Bittles AH: Combining genetics and population history in the study of ethnic diversity in the People's Republic of China. Hum Biol 2006;78:277-293.
30. Chu TX and Levy JA: Injection drug use and HIV/AIDS transmission in China. Cell Res 2005;15:865-869.
31. Yu XF, Chen J, Shao Y, Beyrer C, and Lai S: Two subtypes of HIV-1 among injection-drug users in southern China. Lancet 1998;351:1250.
32. Beyrer C, Razak MH, Lisam K, Chen J, Lui W, and Yu XF: Overland heroin trafficking routes and HIV-1 spread in south and south-east Asia. AIDS 2000;14:75-83.
33. Piyasirisilp S, McCutchan FE, Carr JK, Sanders-Buell E, Liu W, Chen J, Wagner R, Wolf H, Shao Y, Lai S, Beyrer C, and Yu XF: A recent outbreak of human immunodeficiency virus type 1 infection in southern China was initiated by two highly homogeneous, geographically separated strains, circulating recombinant form AE and a novel BC recombinant. J Virol 2000;74:11286-11295.
34. McClutchan FE, Carr JK, Murphy D, Piyasirisilp S, Gao F, Hahn B, Yu XF, Beyrer C, and Birx DL: Precise mapping of recombination breakpoints suggests a common parent of two BC recombinant HIV type 1 strains circulating in China. AIDS Res Hum Retroviruses 2002;18:1135-1140.
35. Depner M, Kormann MS, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Combadiere C, and Kabesch M: CX3CR1 polymorphisms are associated with atopy but not asthma in German children. Int Arch Allergy Immunol 2007;144:91-94.
36. Dimberg J, Dienus O, Lofgren S, Hugander A, and Wagsater D: Polymorphisms of fractalkine receptor CX3CR1 and plasma levels of its ligand CX3CL1 in colorectal cancer patients. Int J Colorectal Dis 2007;22:1195-1200.
37. Plant D, Young HS, Watson RE, Worthington J, and Griffiths CE: The CX3CL1-CX3CR1 system and psoriasis. Exp Dermatol 2006;15:900-903.
38. Simeoni E, Vassalli G, Seydoux C, Ramsay D, Noll G, von Segesser LK, and Fleury S: CCR5, RANTES and CX3CR1 polymorphisms: Possible genetic links with acute heart rejection. Transplantation 2005;80:1309-1315.
39. Li C, Lu SC, Hsieh PS, Huang YH, Huang HI, Ying TH, and Shieh B: Distribution of human chemokine (C-X3-C) receptor 1 (CX3CR1) gene polymorphisms and haplotypes of the CC chemokine receptor 5 (CCR5) promoter in Chinese people, and the effects of CCR5 haplotypes on CCR5 expression. Int J Immunogenet. 2005;32(2):99-106.
40. Liu MX, Wang FS, Hong WG, Wang CQ, Wang B, Jin L, Hou J, and Lei ZY: Distribution of HIV-1 coreceptor CX3CR1 allelic polymorphisms in general population, HIV-1 high-risk group and HIV-1 carriers of Chinese indigenous Han and Uygur people. Chinese J Epidemiol 2003;24(7):595-598