Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE2 production: Functional significance

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 4, 2008, Pages

  Abdullah, Huda Ismail ^a   Pedraza, Paulina L ^a   McGiff, John C ^a   Ferreri, Nicholas R ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Loop of Henle; Nuclear factor of activated T cells; Oxygen consumption; Tumor necrosis factor

Indexed keywords

CALCINEURIN; CALCIUM ION; CALCIUM SENSING RECEPTOR; CYCLOOXYGENASE 2 INHIBITOR; CYCLOSPORIN A; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NUCLEAR FACTOR; OUABAIN; OXYGEN; PROSTAGLANDIN E2; PROTEIN GQ; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CELL FUNCTION; CONTROLLED STUDY; ENZYME SYNTHESIS; EXTRACELLULAR CALCIUM; IN VITRO STUDY; ION TRANSPORT; KIDNEY TUBULE CELL; MALE; MEDULLARY THICK ASCENDING LIMB CELL; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

EID: 57049171968     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.90316.2008     Document Type: Article

References (64)

1. Abdullah HI, Pedraza PL, Hao S, Rodland KD, McGiff JC, Ferreri NR. NFAT regulates calcium sensing receptor-mediated TNF production. Am J Physiol Renal Physiol 290: F1110-F1117, 2006.
2. Abdullah HI, Pedraza PL, McGiff JC, Ferreri NR. CaR activation increases TNF production by mTAL cells via a Gi-dependent mechanism. Am J Physiol Renal Physiol 294: F345-F354, 2008.
3. Attie MF, Gill JR Jr, Stock JL, Spiegel AM, Downs RW Jr, Levine MA, Marx SJ. Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. J Clin Invest 72: 667-676, 1983.
4. Beck N, Singh H, Reed SW, Murdaugh HV, Davis BB. Pathogenic role of cyclic AMP in the impairment of urinary concentrating ability in acute hypercalcemia. J Clin Invest 54: 1049-1055, 1974.
5. Besseghir K, Trimble ME, Stoner L. Action of ADH on isolated medullary thick ascending limb of the Brattleboro rat. Am J Physiol Renal Fluid Electrolyte Physiol 251: F271-F277, 1986.
6. 2+-sensing receptor: central mediator of systemic calcium homeostasis. Annu Rev Nutr 20: 507-533, 2000.
7. 2+ to function as a versatile extracellular first messenger. Recent Prog Horm Res 53: 257-280, 1998.
8. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 81: 239-297, 2001.
9. Brown EM, Vassilev PM, Hebert SC. Calcium ions as extracellular messengers. Cell 83: 679-682, 1995.
10. 2+-sensing receptor: a versatile regulator of diverse cellular functions. Vitam Horm 55: 1-71, 1999.
11. Carney S, Morgan TO. Mechanisms of polyuria of hypercalcemia. Am J Nephrol 6: 230-231, 1986.
12. Carroll MA, McGiff JC, Ferreri NR. Products of arachidonic acid metabolism. Methods Mol Med 86: 385-397, 2003.
13. Chamberlin ME, Mandel LJ. Substrate support of medullary thick ascending limb oxygen consumption. Am J Physiol Renal Fluid Electrolyte Physiol 251: F758-F763, 1986.
14. Chattopadhyay N, Baum M, Bai M, Riccardi D, Hebert SC, Harris HW, Brown EM. Ontogeny of the extracellular calcium-sensing receptor in rat kidney. Am J Physiol Renal Fluid Electrolyte Physiol 271: F736-F743, 1996.
15. +-ATPase in rat renal proximal tubules by dopamine involved DA-1 receptor activation. Naunyn Schmiedebergs Arch Pharmacol 347: 289-295, 1993.
16. 2+. J Biol Chem 273: 15192-15202, 1998.
17. Eng B, Mukhopadhyay S, Vio CP, Pedraza PL, Hao S, Battula S, Sehgal PB, McGiff JC, Ferreri NR. Characterization of a long-term rat mTAL cell line. Am J Physiol Renal Physiol 293: F1413-F1422, 2007.
18. Escalante B, Erlij D, Falck JR, McGiff JC. Effect of cytochrome P450 arachidonate metabolites on ion transport in rabbit kidney loop of Henle. Science 251: 799-802, 1991.
19. Escalante BA, Ferreri NR, Dunn CE, McGiff JC. Cytokines affect ion transport in primary cultured thick ascending limb of Henle's loop cells. Am J Physiol Cell Physiol 266: C1568-C1576, 1994.
20. Ferreri NR, An SJ, McGiff JC. Cyclooxygenase-2 expression and function in the medullary thick ascending limb. Am J Physiol Renal Physiol 277: F360-F368, 1999.
21. Ferreri NR, Escalante BA, Zhao Y, An S, McGiff JC. Angiotensin II induces TNF production by the thick ascending limb: functional implications. Am J Physiol Renal Physiol 274: F148-F155, 1998.
22. Gamba G, Miyanoshita A, Lombardi M, Lytton J, Lee WS, Hediger MA, Hebert SC. Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem 269: 17713-17722, 1994.
23. Giebisch G. Renal potassium transport: mechanisms and regulation. Am J Physiol Renal Physiol 274: F817-F833, 1998.
24. Gimenez I, Forbush B. Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J Biol Chem 278: 26946-26951, 2003.
25. Goldfarb S, Agus ZS. Mechanism of the polyuria of hypercalcemia. Am J Nephrol 4: 69-76, 1984.
26. Greger R. Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev 65: 760-797, 1985.
27. Hebert SC. Extracellular calcium-sensing receptor: implications for calcium and magnesium handling in the kidney. Kidney Int 50: 2129-2139, 1996.
28. Hebert SC. Bartter syndrome. Curr Opin Nephrol Hypertens 12: 527-532, 2003.
29. Hebert SC, Riccardi D, Geibel JP. The calcium sensing receptor. In: Seldin and Giebisch's The Kidney: Physiology and Pathophysiology, edited by Alpern RJ and Hebert SC. New York: Academic, 2007, p. 1785-1802.
30. Hocherl K, Dreher F, Vitzthum H, Kohler J, Kurtz A. Cyclosporine A suppresses cyclooxygenase-2 expression in the rat kidney. J Am Soc Nephrol 13: 2427-2436, 2002.
31. Igarashi P, Vanden Heuvel GB, Payne JA, Forbush B 3rd. Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol Renal Fluid Electrolyte Physiol 269: F405-F418, 1995.
32. 2 inhibits Na-K-2Cl cotransport in medullary thick ascending limb cells. Am J Physiol Cell Physiol 271: C354-C361, 1996.
33. Kim GH, Ecelbarger CA, Mitchell C, Packer RK, Wade JB, Knepper MA. Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop. Am J Physiol Renal Physiol 276: F96-F103, 1999.
34. Knepper MA, Kim GH, Fernandez-Llama P, Ecelbarger CA. Regulation of thick ascending limb transport by vasopressin. J Am Soc Nephrol 10: 628-634, 1999.
35. +-ATPase α1-subunit gene in an MTAL cell line. Am J Physiol Renal Physiol 276: F614-F621, 1999.
36. Kwon TH, Frokiær J, Fernandez-Llama P, Maunsbach AB, Knepper MA, Nielsen S. Altered expression of Na transporters NHE-3, NaPi-II, Na-K-ATPase, BSC-1, and TSC in CRF rat kidneys. Am J Physiol Renal Physiol 277: F257-F270, 1999.
37. + channel in the thick ascending limb of the rat kidney. Am J Physiol Cell Physiol 278: C905-C913, 2000.
38. + channel in the thick ascending limb of the rat kidney. J Gen Physiol 108: 1-11, 1996.
39. Matsuda S, Koyasu S. Mechanisms of action of cyclosporine. Immunopharmacology 47: 119-125, 2000.
40. 2+ handling, and arterial pressure control. Can J Physiol Pharmacol 72: 937-944, 1994.
41. McGiff JC. Bartter's syndrome results from an imbalance of vasoactive hormones. Ann Intern Med 87: 369-372, 1977.
42. McNeil SE, Hobson SA, Nipper V, Rodland KD. Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium. J Biol Chem 273: 1114-1120, 1998.
43. - cotransporter is mediated by regulation of cotransporter trafficking. Am J Physiol Renal Physiol 284: F1145-F1154, 2003.
44. - entry in mouse medullary thick ascending limbs of Henle. Am J Physiol Renal Fluid Electrolyte Physiol 252: F177-F187, 1987.
45. 2+ on renal adenyl cyclase. J Supramol Struct 9: 391-398, 1978.
46. 2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats via sympatholytic and renal effects. Am J Clin Nutr 54: 227S-236S, 1991.
47. - cotransporter activity. Am J Physiol Renal Physiol 281: F819-F825, 2001.
48. Procino G, Carmosino M, Tamma G, Gouraud S, Laera A, Riccardi D, Svelto M, Valenti G. Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells. Kidney Int 66: 2245-2255, 2004.
49. 2+/polyvalent cation-sensing protein in rat kidney. Am J Physiol Renal Physiol 274: F611-F622, 1998.
50. 2+ sensing receptor and PTH/PTHrP receptor in rat kidney. Am J Physiol Renal Fluid Electrolyte Physiol 271: F951-F956, 1996.
51. Sands JM, Naruse M, Baum M, Jo I, Hebert SC, Brown EM, Harris HW. Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct. J Clin Invest 99: 1399-1405, 1997.
52. +-ATPase). Nature 314: 620-622, 1985.
53. 2 on chloride transport across the rabbit thick ascending limb of Henle. J Clin Invest 64: 495-502, 1979.
54. Varela M, Garvin JL. Acute and chronic regulation of thick ascending limb endothelial nitric oxide synthase by statins. J Am Soc Nephrol 15: 269-275, 2004.
55. Wang D, An SJ, Wang WH, McGiff JC, Ferreri NR. CaR-mediated COX-2 expression in primary cultured mTAL cells. Am J Physiol Renal Physiol 281: F658-F664, 2001.
56. Wang D, McGiff JC, Ferreri NR. Regulation of cyclooxygenase isoforms in the renal thick ascending limb: effects of extracellular calcium. J Physiol Pharmacol 51: 587-595, 2000.
57. Wang D, Pedraza PL, Abdullah HI, McGiff JC, Ferreri NR. Calcium-sensing receptor-mediated TNF production in medullary thick ascending limb cells. Am J Physiol Renal Physiol 283: F963-F970, 2002.
58. + channels in rat TAL. Am J Physiol Renal Physiol 273: F421-F429, 1997.
59. + channels in the TAL. Am J Physiol Cell Physiol 271: C103-C111, 1996.
60. + channel in the TAL of the rat kidney. Hypertension 25: 31, 1995.
61. Wang W, Kwon TH, Li C, Frokiær J, Knepper MA, Nielsen S. Reduced expression of Na-K-2Cl cotransporter in medullary TAL in vitamin D-induced hypercalcemia in rats. Am J Physiol Renal Physiol 282: F34-F44, 2002.
62. + channels in rat TAL. Am J Physiol Renal Physiol 273: F421-F429, 1997.
63. Ward DT. Calcium receptor-mediated intracellular signalling. Cell Calcium 35: 217-228, 2004.
64. 2+-sensing receptor mRNAs along the rat nephron. Am J Physiol Renal Physiol 272: F751-F758, 1997.