Urinary oxidative stress markers closely reflect the efficacy of candesartan treatment for diabetic nephropathy

Nephron - Experimental Nephrology

Volumn 111, Issue 1, 2009, Pages

  Yoshida, Shin Ichiro ^a   Hashimoto, Tatsuo ^a   Kihara, Minoru ^a   Imai, Nozomi ^a   Yasuzaki, Hiroaki ^a   Nomura, Kouichirou ^a   Kiuchi, Yoshihiro ^a   Tamura, Kouichi ^a   Ishigami, Tomoaki ^a   Hirawa, Nobuhito ^a   Toya, Yoshiyuki ^a   Kitamura, Hitoshi ^a   Umemura, Satoshi ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II receptor blocker; Diabetic nephropathy; Glomeruli; Mouse models; Oxidative stress; Therapeutic markers; Urinary albumin excretion

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTANE; ALBUMIN; CANDESARTAN; HYDRALAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DIABETIC NEPHROPATHY; DRUG EFFICACY; GLOMERULUS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY INJURY; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; URINARY EXCRETION;

ALBUMINURIA; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BIOLOGICAL MARKERS; DEOXYGUANOSINE; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; DINOPROST; DISEASE MODELS, ANIMAL; HYDRALAZINE; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; TETRAZOLES; TREATMENT OUTCOME; TYROSINE;

EID: 57049167558     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000178764     Document Type: Article

References (34)

1. Shimoike T, Inoguchi T, Umeda F, Nawata H, Kawano K, Ochi H: The meaning of serum levels of advanced glycosylation end products in diabetic nephropathy. Metabolism 2000;49:1030-1035.
2. Hinokio Y, Suzuki S, Hirai M, Suzuki C, Suzuki M, Toyota T: Urinary excretion of 8-oxo-7, 8-dihydro-2′-deoxyguanosine as a predictor of the development of diabetic nephropathy. Diabetologia 2002;45:877-882.
3. Ogawa S, Mori T, Nako K, Kato T, Takeuchi K, Ito S: Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy. Hypertension 2006;47:699-705.
4. Etoh T, Inoguchi T, Kakimoto M, Sonoda N, Kobayashi K, Kuroda J, Sumimoto H, Nawata H: Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibility by interventive insulin treatment. Diabetologia 2003;46:1428-1437.
5. Fan Q, Liao J, Kobayashi M, Yamashita M, Gu L, Gohda T, Suzuki Y, Wang LN, Horikoshi S, Tomino Y: Candesartan reduced advanced glycation end-products accumulation and diminished nitro-oxidative stress in type 2 diabetic KK/Ta mice. Nephrol Dial Transplant 2004;19:3012-3020.
6. Sonta T, Inoguchi T, Matsumoto S, Yasukawa K, Inuo M, Tsubouchi H, Sonoda N, Kobayashi K, Utsumi H, Nawata H: In vivo imaging of oxidative stress in the kidney of diabetic mice and its normalization by angiotensin II type 1 receptor blocker. Biochem Biophys Res Commun 2005;330:415-422.
7. Fujii M, Inoguchi T, Maeda Y, Sasaki S, Sawada F, Saito R, Kobayashi K, Sumimoto H, Takayanagi R: Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice. Kidney Int 2007;72:473-480.
8. Imai N, Hashimoto T, Kihara M, Yoshida S, Kawana I, Yazawa T, Kitamura H, Umemura S: Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis. Lab Invest 2007;87:189-198.
9. Sasaki K, Murohara T, Ikeda H, Sugaya T, Shimada T, Shintani S, Imaizumi T: Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis. J Clin Invest 2002;109:603-611.
10. Kihara M, Umemura S, Yabana M, Sumida Y, Nyui N, Tamura K, Kadota T, Kishida R, Murakami K, Fukamizu A, Ishii M: Dietary salt loading decreases the expressions of neuronal-type nitric oxide synthase and renin in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice. J Am Soc Nephrol 1998;9:355-362.
11. Sato K, Kihara M, Hashimoto T, Matsushita K, Koide Y, Tamura K, Hirawa N, Toya Y, Fukamizu A, Umemura S: Alterations in renal endothelial nitric oxide synthase expression by salt diet in angiotensin type-1a receptor gene knockout mice. J Am Soc Nephrol 2004;15:1756-1763.
12. Hashimoto T, Kihara M, Sato K, Matsushita K, Tanimoto K, Toya Y, Fukamizu A, Umemura S: Expression of cyclooxygenase-2 in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice. Nephron Physiol 2006;102:1-8.
13. Oudit GY, Herzenberg AM, Kassiri Z, Wong D, Reich H, Khokha R, Crackower MA, Backx PH, Penninger JM, Scholey JW: Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. Am J Pathol 2006;168:1808-1820.
14. Hashimoto T, Kihara M, Ishida J, Imai N, Yoshida S, Toya Y, Fukamizu A, Kitamura H, Umemura S: Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2006;26:1267-1272.
15. Hashimoto T, Kihara M, Imai N, Yoshida S, Shimoyamada H, Yasuzaki H, Ishida J, Toya Y, Kiuchi Y, Hirawa N, Tamura K, Yazawa T, Kitamura H, Fukamizu A, Umemura S: Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis. Am J Pathol 2007;171:1705-1712.
16. Yamaguchi Y, Yamada K, Yoshikawa N, Nakamura K, Haginaka J, Kunitomo M: Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 2006;79:2474-2479.
17. Whaley-Connell AT, Chowdhury NA, Hayden MR, Stump CS, Habibi J, Wiedmeyer CE, Gallagher PE, Tallant EA, Cooper SA, Link CD, Ferrario C, Sowers JR: Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat. Am J Physiol Renal Physiol 2006;291:F1308-F1314.
18. Nagase M, Yoshida S, Shibata S, Nagase T, Gotoda T, Ando K, Fujita T: Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors. J Am Soc Nephrol 2006;17:3438-3446.
19. Shibata S, Nagase M, Yoshida S, Kawachi H, Fujita T: Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 2007;49:355-364.
20. Gohda T, Tanimoto M, Kaneko S, Shibata T, Funabiki K, Horikoshi S, Tomino Y: Minor gene effect of leptin receptor variant on the body weight in KK/Ta mice. Diabetes Obes Metab 2006;8:581-584.
21. Kobayashi M, Kimura H, Liao J, Abe M, Hirose S, Tomino Y: Measurement of mouse urinary type IV collagen using time-resolved fluoroimmunoassay. Anal Sci 2003;19:205-210.
22. Shike T, Gohda T, Tanimoto M, Kobayashi M, Makita Y, Funabiki K, Horikoshi S, Hirose S, Shirai T, Tomino Y: Chromosomal mapping of a quantitative trait locus for the development of albuminuria in diabetic KK/Ta mice. Nephrol Dial Transplant 2005;20:879-885.
23. Sharma K, McCue P, Dunn SR: Diabetic kidney disease in the db/db mouse. Am J Physiol Renal Physiol 2003;284:F1138-F1144.
24. Kakimoto M, Inoguchi T, Sonta T, Yu HY, Imamura M, Etoh T, Hashimoto T, Nawata H: Accumulation of 8-hydroxy-2′-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. Diabetes 2002;51:1588-1595.
25. Nangaku M: Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 2006;17:17-25.
26. Ye M, Wysocki J, Naaz P, Salabat MR, LaPointe MS, Batlle D: Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? Hypertension 2004;43:1120-1125.
27. Agarwal R: Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade. Am J Physiol Renal Physiol 2003;284:F863-F869.
28. Price DA, Porter LE, Gordon M, Fisher ND, De'Oliveira JM, Laffel LM, Passan DR, Williams GH, Hollenberg NK: The paradox of the low-renin state in diabetic nephropathy. J Am Soc Nephrol 1999;10:2382-2391.
29. Anderson S, Jung FF, Ingelfinger JR: Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am J Physiol 1993;265:F477-F486.
30. Zorad S, Dou JT, Benicky J, Hutanu D, Tybitanclova K, Zhou J, Saavedra JM: Long-term angiotensin II AT1 receptor inhibition produces adipose tissue hypotrophy accompanied by increased expression of adiponectin and PPARgamma. Eur J Pharmacol 2006;552:112-122.
31. Shepherd AM, Irvine NA: Differential hemodynamic and sympathoadrenal effects of sodium nitroprusside and hydralazine in hypertensive subjects. J Cardiovasc Pharmacol 1986;8:527-533.
32. Bray GA: Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications. Int J Obes Relat Metab Disord 2000;24(suppl 2):S8-S17.
33. Nonogaki K: New insights into sympathetic regulation of glucose and fat metabolism. Diabetologia 2000;43:533-549.
34. Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS: Role of leptin in fat regulation. Nature 1996;380:677.