An investigation into keratinolytic enzymes to enhance ungual drug delivery

International Journal of Pharmaceutics

Volumn 332, Issue 1-2, 2007, Pages 196-201

  Mohorcic M ^a   Torkar, A ^b   Friedrich, J ^a   Kristl, J ^b   Murdan, S ^c  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Drug permeation; Keratinase; Nail; Permeability; Ungual drug delivery

Indexed keywords

ENZYME; KERATIN; KERATINASE; TOPICAL AGENT;

ANIMAL TISSUE; ARTICLE; COW; DRUG DELIVERY SYSTEM; DRUG PENETRATION; HOOF AND CLAW; HUMAN; HUMAN TISSUE; INTERCELLULAR SPACE; NAIL; NONHUMAN; PARTITION COEFFICIENT; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TEMPERATURE; TOPICAL TREATMENT;

ADMINISTRATION, TOPICAL; ADRENAL CORTEX HORMONES; ANIMALS; ANTIFUNGAL AGENTS; CATTLE; CELL MEMBRANE PERMEABILITY; DIFFUSION CHAMBERS, CULTURE; HOOF AND CLAW; HUMANS; KERATINS; KERATOLYTIC AGENTS; METFORMIN; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; NAIL DISEASES; NAILS; PEPTIDE HYDROLASES; TIME FACTORS;

EID: 33846888289     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.09.042     Document Type: Article

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