Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures

Journal of Neuroscience Research

Volumn 86, Issue 15, 2008, Pages 3393-3400

  Yang, Dehua ^a   Peng, Changgeng ^a   Li, Xuping ^a   Fan, Xiaolan ^a   Li, Liang ^a   Ming, Ming ^a   Chen, Sheng ^a   Le, Weidong ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

BDNF; DA; GDNF; Neurodegeneration; Pitx3; Primary astrocytes

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; PROTEIN ANTIBODY; ROTENONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PITX3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ASTROCYTE; CELL COUNT; CELL NUCLEUS; CELL PROTECTION; CONTROLLED STUDY; CULTURE MEDIUM; DOPAMINERGIC NERVE CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; MESENCEPHALON; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DOPAMINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE THERAPY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; NERVE DEGENERATION; NEURONS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROTENONE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 57049138146     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21774     Document Type: Article

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