Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5′ UTR of the NRAS proto-oncogene

Biochemistry

Volumn 47, Issue 48, 2008, Pages 12664-12669

  Kumari, Sunita ^a   Bugaut, Anthony ^a   Balasubramanian, Shankar ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; JOINTS (STRUCTURAL COMPONENTS); NUCLEIC ACIDS; RNA; TRANSLATION (LANGUAGES);

FORMING SEQUENCES; SECONDARY STRUCTURES; TRANSLATION REGULATIONS; TRANSLATION REPRESSIONS; TRANSLATIONAL EFFECTS; TRANSLATIONAL LEVELS; UNTRANSLATED REGIONS;

THERMODYNAMIC STABILITY;

GUANINE; MESSENGER RNA;

ARTICLE; CIRCULAR DICHROISM; ONCOGENE N RAS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTO ONCOGENE; THERMODYNAMICS; THERMOSTABILITY; TRANSLATION REGULATION; ULTRAVIOLET SPECTROSCOPY; UNTRANSLATED REGION;

5' UNTRANSLATED REGIONS; BASE SEQUENCE; CELL-FREE SYSTEM; G-QUADRUPLEXES; GENES, RAS; HUMANS; MUTATION; NUCLEIC ACID DENATURATION; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS P21(RAS); RNA; RNA STABILITY; RNA, MESSENGER; THERMODYNAMICS; TRANSITION TEMPERATURE;

EID: 57049135230     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8010797     Document Type: Article

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