Solanum indicum ssp. distichum extract is effective against L-NAME-induced hypertension in rats

Fundamental and Clinical Pharmacology

Volumn 22, Issue 6, 2008, Pages 693-699

  Bahgat, Ashraf ^a   Abdel Aziz, Heba ^b   Raafat, Mohamed ^a   Mahdy, Amina ^a   El Khatib, Aiman S ^a   Ismail, Ahmed ^c   Khayyal, Mohamed T ^a  

^a CAIRO UNIVERSITY   (Egypt)

^b Sinai University   (Egypt)

^c Sekem Academy   (Egypt)

Author keywords

Antihypertensive agents; Chlorogenic acids; Herbal medicinal product; L NAME; Solanum anguivi; Solanum indicum ssp. distichum

Indexed keywords

CHLOROGENIC ACID; N(G) NITROARGININE METHYL ESTER; PLANT EXTRACT; SOLANUM INDICUM EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; DRUG EFFICACY; HYPERTENSION; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; RAT; SOLANUM INDICUM; SYSTOLIC BLOOD PRESSURE;

ADMINISTRATION, ORAL; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUIT; HYPERTENSION; MALE; NG-NITROARGININE METHYL ESTER; PLANT EXTRACTS; RATS; RATS, WISTAR; SOLANUM; TIME FACTORS;

EID: 57049130348     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2008.00627.x     Document Type: Article

References (27)

1. Ripperger H., Himmelreich U. Anguivine and isoanguivine, steroid alkaloid glycosides from Solanum anguivi. Phytochemistry (1994) 37 1725 1727.
2. Honbu T., Ikeda T., Zhu X.H. et al. New steroidal glycosides from the fruits of Solanum anguivi. J. Nat. Prod. (2002) 65 1918 1920.
3. Zhu X.H., Ikeda T., Nohara T. Studies on the constituents of solanaceous plants. (46). Steroidal glycosides from the fruits of Solanum anguivi. Chem. Pharm. Bull. (2000) 48 568 570.
4. Rubaihayo E.B. Conservation and use of traditional vegetables in Uganda. Proc. IPGRI Int. Workshop Genetic Resources Traditional Vegetables Africa Conservation Use, Nairobi, Kenya, 29-31 August, 1995.
5. Rossoni G., Manfredi B., De Gennaro Colonna V., Berti M., Guazzi M., Berti F. Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat. Br. J. Pharmacol. (2007) 150 567 576.
6. Pechanova O., Bernatova I., Babal P. et al. Red wine polyphenols prevent cardiovascular alterations in L-NAME-induced hypertension. J. Hypertens. (2004) 22 1551 1559.
7. Khayyal M.T., El-Ghazaly M.A., Abdallah D.M., Nassar N.N., Okpanyi S.N., Kreuter M.H. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Drug Res. (2002) 52 797 802.
8. Sreevidya N., Mehrotra S. A spectrophotometric method for estimation of alkaloids precipitable with Dragendorff's reagent in plant materials. J. AOAC Int. (2003) 86 1124 1127.
9. Johnson R.A., Freeman R.H. Sustained hypertension in the rat induced by chronic blockade of nitric oxide production. Am. J. Hypertens. (1992) 5 919 922.
10. Friedman M., Henika P.R., Mackey B.E. Feeding of potato, tomato and eggplant alkaloids affects food consumption and body and liver weights in mice. J. Nutr. (1996) 126 989 999.
11. Mensinga T.T., Sips A.J., Rompelberg C.J. et al. Potato glycoalkaloids and adverse effects in humans: an ascending dose study. Regul. Toxicol. Pharmacol. (2005) 41 66 72.
12. Baylis C., Harton P., Engels K. Endothelial derived relaxing factor controls renal hemodynamics in the normal rat kidney. J. Am. Soc. Nephrol. (1990) 1 875 881.
13. Baylis C., Mitruka B., Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J. Clin. Invest. (1992) 90 278 281.
14. Zatz R., Baylis C. Chronic Nitric Oxide inhibition model six years on. Hypertension (1998) 32 958 964.
15. Pegoraro A.A., Carretero O.A., Sigmon D.H., Beierwaltes W.H. Sympathetic modulation of endothelium derived relaxing factor. Hypertension (1992) 19 643 647.
16. Qiu C., Muchant D., Beierwaltes W.H., Racusen L., Baylis C. Evolution of chronic nitric oxide inhibition hypertension: relationship to renal function. Hypertension (1998) 31 21 26.
17. Reid I.A., Bui H., Chou L. Role of nitric oxide in the renin and heart rate response to beta-adrenergic stimulation. Hypertension (1994) 23 I49 53.
18. Usui M., Egashira K., Kitamoto S. et al. Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats. Hypertension (1999) 34 546 551.
19. Vaziri N.D., Wang X.Q., Oveisi F., Rad B. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension (2000) 36 142 146.
20. Suzuki A., Kagawa D., Ochiai R., Tokimitsu I., Saito I. Green coffee bean extract and its metabolites have a hypotensive effect in spontaneously hypertensive rats. Hypertens. Res. (2002) 25 99 107.
21. Suzuki A., Yamamoto N., Jokura H. et al. Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats. J. Hypertens. (2006) 24 1065 1073.
22. Ochiai R., Jokura H., Suzuki A. et al. Green coffee bean extract improves human vasoreactivity. Hypertens. Res. (2004) 27 731 737.
23. Kozuma K., Tsuchiya S., Kohori J., Hase T., Tokimitsu I. Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertens. Res. (2005) 28 711 718.
24. Wantanabe T., Arai Y., Mitsui Y. et al. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin. Exp. Hypertens. (2006) 28 439 449.
25. +- ATPase activity and blood pressure in young spontaneously hypertensive rats. Hypertension (1987) 9 571 575.
26. Workman ML, Paller MS. Cardiovascular and endocrine effects of potassium in spontaneously hypertensive rats. Am. J. Physiol. (1985) 18 H907 H913.
27. Suzuki H., Kondo K., Saruta T. Inhibitory effect of potassium on blood pressure in DOCA salt hypertension in rats. Acta Endocrinol. (1981) 97 525 532.