Association of the GNAS locus with severe malaria

Human Genetics

Volumn 124, Issue 5, 2008, Pages 499-506

  Auburn, Sarah ^a,m   Diakite, Mahamadou ^a   Fry, Andrew E ^a   Ghansah, Anita ^b   Campino, Susana ^a   Richardson, Anna ^a   Jallow, Muminatou ^c   Sisay Joof, Fatou ^c   Pinder, Margaret ^c   Griffiths, Michael J ^d   Peshu, Norbert ^d   Williams, Thomas N ^d,e   Marsh, Kevin ^e   Molyneux, Malcolm E ^f,h   Taylor, Terrie E ^g,i   Koram, Kwadwo A ^b   Oduro, Abraham R ^j   Rogers, William O ^k   Rockett, Kirk A ^a   Haldar, Kasturi ^l   Kwiatkowski, Dominic P ^a,m   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b University of Ghana   (Ghana)

^c MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^f MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^g UNIVERSITY OF MALAWI   (Malawi)

^h LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

ⁱ MICHIGAN STATE UNIVERSITY   (United States)

^j NAVRONGO HEALTH RESEARCH CENTRE   (Ghana)

^k NAVAL MEDICAL RESEARCH CENTER   (United States)

^l NORTHWESTERN UNIVERSITY   (United States)

^m WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ARTICLE; CASE CONTROL STUDY; CLINICAL TRIAL; DISEASE SEVERITY; DNA POLYMORPHISM; GAMBIA; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GHANA; HUMAN; KENYA; MALARIA; MALARIA FALCIPARUM; MALAWI; META ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTOZOAL GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW;

AFRICA; ALLELES; ANIMALS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; ERYTHROCYTES; GENE FREQUENCY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HAPLOTYPES; HUMANS; INFANT; INFANT, NEWBORN; LINKAGE DISEQUILIBRIUM; MALARIA; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION;

PLASMODIUM FALCIPARUM;

EID: 57049102286     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-008-0575-8     Document Type: Article

References (23)

1. Adams JH, Blair PL, Kaneko O, Peterson DS (2001) An expanding ebl family of Plasmodium falciparum. Trends Parasitol 17:297-299
2. Aidoo M, Terlouw DJ, Kolczak MS, McElroy PD, ter Kuile FO, Kariuki S, Nahlen BL, Lal AA, Udhayakumar V (2002) Protective effects of the sickle cell gene against malaria morbidity and mortality. Lancet 359:1311-1312
3. Cowman AF, Crabb BS (2006) Invasion of red blood cells by malaria parasites. Cell 124:755-766
4. Gonzalez JM, Portillo MC, Saiz-Jimenez C (2005) Multiple displacement amplification as a pre-polymerase chain reaction (pre-PCR) to process difficult to amplify samples and low copy number sequences from natural environments. Environ Microbiol 7:1024-1028
5. Harrison T, Samuel BU, Akompong T, Hamm H, Mohandas N, Lomasney JW, Haldar K (2003) Erythrocyte G protein-coupled receptor signaling in malarial infection. Science 301:1734-1736
6. Hill AV, Allsopp CE, Kwiatkowski D, Anstey NM, Twumasi P, Rowe PA, Bennett S, Brewster D, McMichael AJ, Greenwood BM (1991) Common west African HLA antigens are associated with protection from severe malaria. Nature 352:595-600
7. Ihaka R, Gentleman R (1996) R: A language for data analysis and graphics. J Comput Graph Stat 5:299-314
8. Ioannidis JP (2003) Genetic associations: False or true? Trends Mol Med 9:135-138
9. Kavvoura FK, Ioannidis JP (2007) Methods for meta-analysis in genetic association studies: A review of their potential and pitfalls. Hum Genet 123:1-14
10. Kazeem GR, Farrall M (2005) Integrating case-control and TDT studies. Ann Hum Genet 69:329-335
11. Lauer S, VanWye J, Harrison T, McManus H, Samuel BU, Hiller NL, Mohandas N, Haldar K (2000) Vacuolar uptake of host components, and a role for cholesterol and sphingomyelin in malarial infection. EMBO J 19:3556-3564
12. Lewontin RC, Kojima K (1960) The evolutionary dynamics of complex polymorphisms. Evolution 14:458-472
13. Molyneux ME, Taylor TE, Wirima JJ, Borgstein A (1989) Clinical features and prognostic indicators in paediatric cerebral malaria: A study of 131 comatose Malawian children. Q J Med 71:441-459
14. Murphy SC, Samuel BU, Harrison T, Speicher KD, Speicher DW, Reid ME, Prohaska R, Low PS, Tanner MJ, Mohandas N, Haldar K (2004) Erythrocyte detergent-resistant membrane proteins: Their characterization and selective uptake during malarial infection. Blood 103:1920-1928
15. Oldham WM, Hamm HE (2008) Heterotrimeric G protein activation by G-protein-coupled receptors. Nat Rev Mol Cell Biol 9:60-71
16. Purcell S, Cherny SS, Sham PC (2003) Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19:149-150
17. Samuel BU, Mohandas N, Harrison T, McManus H, Rosse W, Reid M, Haldar K (2001) The role of cholesterol and glycosylphosphatidylinositol-anchored proteins of erythrocyte rafts in regulating raft protein content and malarial infection. J Biol Chem 276:29319-29329
18. Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI (2005) The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434:214-217
19. Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516
20. Teo YY, Fry AE, Sanjoaquin MA, Pederson B, Small KS, Rockett KA, Kwiatkowski DP, Clark TG (2008) Assessing genuine parents-offspring trios for genetic association studies. Hum Hered 67(1):26-37
21. Thompson MD, Cole DE, Jose PA (2008) Pharmacogenomics of G protein-coupled receptor signaling: Insights from health and disease. Mol Biol 448:77-107
22. Weinstein LS, Chen M, Xie T, Liu J (2006) Genetic diseases associated with heterotrimeric G proteins. Trends Pharmacol Sci 27:260-266
23. Zhang L, Cui X, Schmitt K, Hubert R, Navidi W, Arnheim N (1992) Whole genome amplification from a single cell: Implications for genetic analysis. Proc Natl Acad Sci USA 89:5847-5851