Association of apolipoprotein A5 gene-1131T/C polymorphism with serum lipids and carotid intima-media thickness in patients with type 2 diabetes mellitus

Journal of Sichuan University (Medical Science)

Volumn 39, Issue 6, 2008, Pages

  Qiao, Yan ^a   Liu, Rui ^a   Tian, Hao ming ^a   Liu, Yu ^a   Qiang, Ou ^a   Liu, Bing wen ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

A5 gene polymorphism; Apolipoprotein; Carotid intima media thickness; Triglyceride; Type 2 diabetes mellitus

Indexed keywords

EID: 57049096909     PISSN: 1672173X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Pennacchio LA, Olivier M, Hubacek JA, et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science, 2001;294(5540): 169-173.
2. van der Vliet HN, Sammels MG, Leegwater AC, et al. Apolipoprotein A-V, a novel apolipoprotein associated with an early phase of liver regeneration. J Biol Chem, 2001;276(48): 44512-44520.
3. Pennacchio LA, Rubin EM. Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice. Arterioscler Thromb Vasc Biol, 2003;23(4):529-534.
4. Yen SK, Cheng XQ, Song YH. et al. Apolipoprotein A5 gene polymorphism - 1131T→C: association with plasma lipids and type 2 diabetes mellitus with coronary heart disease in Chinese. Chin Chem Lab Med, 2005;43(6):607-612.
5. Geurian K, Pinson JB, Weart CW. The triglyceride connection in atherosclerosis. Ann Pharmacother. 1992;26(9):1109-1117.
6. Erlich HA. Principles and applications for DNA amplification. In: Higuchi R. PCR technology. New York: Stockton Press, 1989:36.
7. Talmud PJ, Hawe E, Martin S, et al. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum Mol Genet, 2002;11 (24):3039-3046.
8. Pennacchio LA, Olivier M, Hubacek JA, et al. Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet, 2002;11(24):3031-3038.
9. Nabika T, Nasreen S, Kobayashi S, et al. The genetic effect of the apoprotein A V gene on the serum triglyceride level in Japanese. Atherosclerosis, 2002;65(2):201-204.
10. Aouizerat BE, Kulkarni M, Heilbron D, et al. Genetic analysis of a polymorphism in the human apoA - V gene: effect on plasma lipids. J Lipid Res, 2003;44(6):1167-1173.
11. van der Vliet HN, Schaap FG, Levels JH, et al. Adenoviral overexpression of apolipoprotein A V reduces serum levels of triglycerides and cholesterol in mice. Biochem Biophys Res Commun, 2002;295(5):1156-1159.
12. Merkel M, Loeffler B, Kluger M, et al. Apolipoprotein A V accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J Biol Chem, 2005;280(22):21553- 21560.
13. Grosskopf I, Baroukh N, Lee SJ, et al. Apolipoprotein A- V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants. Arterioscler Thromb Vasc Biol, 2005;25(12):2573-2579.
14. Baroukh N, Bauge E, Akiyama J, et al. Analysis of apolipoprotein A5, C3, and plasma triglyceride concentrations in genetically engineered mice. Arterioscler Thromb Vasc Biol, 2004;24(7):1297-1302.
15. Elosua R, Ordovas JM, Cupples LA, et al. Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study. J Lipid Res, 2006;47(5):990-996.