Rhamnose catabolism in Bacteroides thetaiotaomicron is controlled by the positive transcriptional regulator RhaR

Research in Microbiology

Volumn 159, Issue 9-10, 2008, Pages 678-684

  Patel, Ekta H ^a   Paul, Lynthia V ^a   Patrick, Sheila ^b   Abratt, Valerie R ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Bacteroides thetaiotaomicron; Carbohydrate utilisation; Lactaldehyde reductase; Rhamnose catabolism

Indexed keywords

GLUCOSE; LACTALDEHYDE; RHAMNOSE;

ARTICLE; BACTEROIDES THETAIOTAOMICRON; CATABOLISM; CONTROLLED STUDY; ENZYME ASSAY; GENE; GENE CLUSTER; GENE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHA GENE; RHAO GENE; RHAR GENE; TRANSCRIPTION REGULATION;

ALCOHOL OXIDOREDUCTASES; BACTERIAL PROTEINS; BACTEROIDES; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTATION; PROPYLENE GLYCOLS; RHAMNOSE; TRANS-ACTIVATORS; TRANSCRIPTIONAL ACTIVATION;

BACTEROIDES THETAIOTAOMICRON;

EID: 56949093168     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/j.resmic.2008.09.002     Document Type: Article

References (36)

1. Aiba H., Adhya S., and de Crombrugghe B. Evidence for two functional gal promoters in intact Escherichia coli cells. J. Biol. Chem. 256 (1981) 11905-11910
2. Altschul S.F., Madden T.L., Schäffer A.A., Zhang J., Zhang Z., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acid Res. 25 (1997) 3389-3402
3. Baldomà L., and Aguilar J. Metabolism of l-fucose and l-rhamnose in Escherichia coli: aerobic-anaerobic regulation of l-lactaldehyde dissimilation. J. Bacteriol 170 (1988) 416-421
4. Bayley D.P., Rocha E.R., and Smith C.J. Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure. FEMS Microbiol. Lett. 193 (2000) 149-154
5. Berríos-Rivera S., San K.-Y., and Bennett G.N. The effect of carbon sources and lactate dehydrogenase deletion on 1,2-propanediol production in Escherichia coli. J. Ind. Microbiol. Biotechnol 30 (2003) 34-40
6. Boronat A., and Aguilar J. Metabolism of l-fucose and l-rhamnose in Escherichia coli: differences in induction of propanediol oxidoreductase. J. Bacteriol 147 (1981) 181-185
7. Chen Y.M., Lu Z., and Lin E.C.C. NAD-linked aldehyde dehydrogenase for aerobic utilization of l-fucose and l-rhamnose by Escherichia coli. J. Bacteriol 169 (1987) 3289-3294
8. Chen Y.M., Tobin J.F., Zhu Y., Schleif R.F., and Lin E.C. Cross-induction of the l-fucose system by l-rhamnose in Escherichia coli. J. Bacteriol 169 (1987) 3712-3719
9. Cheng Q., Paszkiet B.J., Shoemaker N.B., Gardner J.F., and Salyers A.A. Integration and excision of a Bacteroides conjugative transposon, CTnDOT. J. Bacteriol 182 (2000) 4035-4043
10. Eikmanns B.J.N., Thumb-Shmitz L., Eggeling L., Lüdtke K.U., and Sahm H. Nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase. Microbiology 140 (1994) 1817-1828
11. Gallegos M.T., Schleif R., Bairoch A., Hoffman K., and Ramos J.L. AraC/XylS family of transcriptional regulators. Microbiol. Mol. Biol. Rev. 61 (1997) 393-410
12. Holdeman L.V., and Moore W.E.C. Anaerobe laboratory manual. 4th ed. (1972), Virginia Polytechnic Institute and State University Anaerobe Laboratory, Blacksburg, VA
13. Hooper L.V., Xu J., Falk P.G., Midtvedt T., and Gordon J.I. A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 9833-9838
14. Huang K.X., Rudolph F.B., and Bennett G.N. Characterization of methylglyoxal synthase from Clostridium acetobutylicum ATCC 824 and its use in the formation of 1,2-Propanediol. Appl. Environ. Microbiol. 65 (1999) 3244-3247
15. Ish-Horowicz D., and Burke J.F. Rapid and efficient cosmid cloning. Nucleic Acids Res. 9 (1981) 2989-2998
16. Jones L.R., and Riddick J.A. Colorimetric determination of 1,2-propanediol and related compounds. Anal. Chem. 29 (1957) 1214-1215
17. Jousimies-Somer H.R., Summanen P., Citron D.M., Baron E.J., Wexler H.M., and Finegold S.M. Wadsworth-KTL anaerobic bacteriology manual. 6th ed. (2002), Star Publishing Company, Belmont, CA
18. Li L.Y., Shoemaker N.B., and Salyers A.A. Location and characteristics of the transfer region of a Bacteroides conjugative transposon and regulation of transfer genes. J. Bacteriol 177 (1995) 4992-4999
19. Moralejo P., Egan S.M., Hidalgo E., and Aguilar J. Sequencing and characterisation of a gene cluster encoding the enzymes for l-rhamnose metabolism in Escherichia coli. J. Bacteriol 175 (1993) 5585-5594
20. Obradors N., Cabiscol E., Aguilar J., and Ros J. Site-directed mutagenesis studies of the metal-binding center of the iron-dependent propanediol oxidoreductase from Escherichia coli. Eur. J. Biochem. 258 (1998) 207-213
21. Patrick S., and Duerden B.I. Non-sporing Gram negative anaerobes. In: Gillespie S.H., and Hawkey P.M. (Eds). Principles and practice of clinical bacteriology. 2nd ed (2006), J Wiley Sons, London 541-556
22. Power J. The l-rhamnose genetic system in Escherichia coli K-12. Genetics 55 (1966) 557-568
23. Reid M.F., and Fewson C.A. Molecular characterization of microbial alcohol dehydrogenases. Crit. Rev. Microbiol. 20 (1994) 13-56
24. Robertson K.P., Smith C.J., Gough A.M., and Rocha E.R. Characterization of Bacteroides fragilis hemolysins and regulation and synergistic interactions of HlyA and HlyB. Infect. Immun 74 (2006) 2304-2306
25. Salyers A.A., Gupta A., and Wang Y. Human intestinal bacteria as a reservoir for antibiotic resistance genes. Trends Microbiol. 9 (2004) 412-416
26. Salyers A.A., Vercelloti J., West S., and Wilkins T. Fermentation of mucin and plant polysaccharide by strains of Bacteroides from the human colon. Appl. Environ. Microbiol. 33 (1977) 319-322
27. Salyers A.A., West S., Vercelloti J., and Wilkins T. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl. Environ. Microbiol. 34 (1977) 529-533
28. Sambrook J.T., Fritsch E.F., and Maniatis T. Molecular cloning: a laboratory manual. 2nd ed. (1989), Cold Spring Harbour, NY
29. Sanger F., Nicklen S., and Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. U.S.A. 74 (1977) 5463-5467
30. Simon R., Priefer U., and Puhler A. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. J. Biotechnol 1 (1983) 784-791
31. Tobin J.F., and Schleif R.F. Positive regulation of the Escherichia coli l-rhamnose operon is mediated by products of tandemly repeated regulatory genes. J. Mol. Biol. 196 (1987) 789-799
32. Van Tassel R.L., and Wilkins T.D. Isolation of auxotrophs of B. fragilis. Can. J. Microbiol. 24 (1978) 1619-1621
33. Varel V.H., and Bryant M.P. Nutritional features of Bacteroides fragilis subsp. Fragilis. Appl. Microbiol. 28 (1974) 251-257
34. Via P., Badia J., Baldoma L., Obradors N., and Aguilar J. Transcriptional regulation of the Escherichia coli rhaT gene. Microbiology 142 (1996) 1833-1840
35. Wehnert G.U., Abratt V.R., and Woods D.R. Molecular analysis of a gene from Bacteroides fragilis involved in metronidazole resistance in Escherichia coli. Plasmid 27 (1992) 242-245
36. Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., and Gordon J.I. A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science 299 (2003) 2074-2076