Evaluation of immune responses and protective efficacy in a goat model following immunization with a coctail of recombinant antigens and a polyprotein of Mycobacterium avium subsp. paratuberculosis

Vaccine

Volumn 27, Issue 1, 2009, Pages 123-135

  Kathaperumal, Kumanan ^a   Kumanan, Vijayarani ^a   McDonough, Sean ^b   Chen, Li Hsuen ^a,d   Park, Sung Un ^a   Moreira, Maria A S ^a   Akey, Bruce ^a   Huntley, John ^c   Chang, Chao Fu ^a,d   Chang, Yung Fu ^a  

^a College of Veterinary Medicine ^*  (United States)

^b Department of Obstetrics Gynecology   (United States)

^c DEPARTMENT OF AGRICULTURE AND FOOD WESTERN AUSTRALIA   (Australia)

^d CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

85 complex; DDA; Johne's disease; Mycobacterium avium subsp. paratuberculosis; Polyprotein; Recombinant protein; SOD; Vaccine trial

Indexed keywords

85A ANTIGEN; 85B ANTIGEN; ADJUVANT; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; MAP74F PROTEIN; POLYPROTEIN; RECOMBINANT ANTIGEN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; AUTOPSY; BOOSTER IMMUNIZATION; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; FLOW CYTOMETRY; GENE EXPRESSION; GOAT; HISTOPATHOLOGY; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MYCOBACTERIUM PARATUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PARATUBERCULOSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVACCINATION;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; GOAT DISEASES; GOATS; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; PARATUBERCULOSIS; POLYPROTEINS; TH1 CELLS; VACCINATION; VACCINES, SYNTHETIC;

EID: 56949091045     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.10.019     Document Type: Article

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