Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors

Journal of Controlled Release

Volumn 132, Issue 3, 2008, Pages 200-207

  Fretz, Marjan M ^a   Lacombe, Marie ^b   Prakash, Jai ^c   Nguyen, Tri Q ^d   Goldschmeding, Roel ^d   Pato, Janos ^e  

^a Emmy) M   (Netherlands)

^b Kreatech Biotechnology BV   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e Vichem Chemie Ltd   (Hungary)

Author keywords

Drug targeting; Fibrosis; Kidney; Kinase inhibitors; Linker technology

Indexed keywords

DRUG TARGETING; FIBROSIS; KIDNEY; KINASE INHIBITORS; LINKER TECHNOLOGY;

ACTIVATION ANALYSIS; BIOACTIVITY; CELLS; GENE EXPRESSION; PLATINUM;

CYTOLOGY;

4 [3 (2 PYRIDINYL) 1H PYRAZOL 4 YL]QUINOLINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GROWTH FACTOR; LINK PROTEIN; LY 364947; LYSOZYME; PHOSPHOTRANSFERASE INHIBITOR; PLATINUM; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING AND TRANSPORT; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG RELEASE; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG TARGETING; ENDOCYTOSIS; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; ENDOCYTOSIS; EPIDERMAL GROWTH FACTOR; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY TUBULES, PROXIMAL; KINETICS; MURAMIDASE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRROLES; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 56949089687     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.08.013     Document Type: Article

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