Synthesis of biologically active N-methyl derivatives of amidines and cyclized five-membered products of amidines with oxalyl chloride

European Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2008, Pages 2824-2830

  Sondhi, Sham M ^a   Dinodia, Monica ^a   Jain, Shubhi ^a   Kumar, Ashok ^b  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b LLRM MEDICAL COLLEGE   (India)

Author keywords

Acylating agent; Analgesic; Anti inflammatory; Methyl iodide; Oxalyl chloride

Indexed keywords

[4,5 DIOXO 2 (PYRIDIN 2 YL) 4,5 DIHYDROIMIDAZOL 1 YL] 4 METHYLBENZENESULFONAMIDE; [4,5 DIOXO 2 (PYRIDIN 4 YL) 4,5 DIHYDROIMIDAZOL 1 YL] 4 METHOXYBENZENESULFONAMIDE; [4,5 DIOXO 2 (PYRIDIN 4 YL) 4,5 DIHYDROIMIDAZOL 1 YL]BENZENESULFONAMIDE; AMIDINE; METHYL (4 METHYLPHENYLSULFONAMIDO)PICOLINAMIDINE; METHYL (METHYLPHENYLSULFONAMIDO)ISONICOTINAMIDINE; METHYL IODIDE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; MALE; MOUSE; NONHUMAN; RAT;

ADMINISTRATION, ORAL; AMIDINES; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CHLORIDES; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; EDEMA; FEMALE; MALE; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXALATES; PAIN; PAIN MEASUREMENT; RATS; RATS, WISTAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 56849121655     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.10.005     Document Type: Article

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