Extended-release, once-daily morphine (Avinza) for the treatment of chronic nonmalignant pain: Effect on pain, depressive symptoms, and cognition

Pain Medicine

Volumn 9, Issue 8, 2008, Pages 985-993

  Panjabi, Sumeet S ^a,d   Panjabi, Ravi S ^b   Shepherd, Marvin D ^c   Lawson, Kenneth A ^c   Johnsrud, Michael ^c   Barner, Jamie ^c  

^a ELAN PHARMACEUTICALS   (United States)

^b Advanced Pain Management and Rehab Group Inc   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d NONE   (United States)

Author keywords

Chronic Pain; Cognitive Function; Depressive Symptoms; Morphine; Nonmalignant Pain

Indexed keywords

MORPHINE SULFATE; SHORT ACTING DRUG;

ADULT; AGED; ANALGESIC ACTIVITY; ARTICLE; BECK DEPRESSION INVENTORY; CHRONIC PAIN; CLINICAL TRIAL; COGNITION; CONFUSION; DEPRESSION; DIGIT SYMBOL SUBSTITUTION TEST; DROWSINESS; DRUG EFFICACY; DRUG ERUPTION; DRUG HYPERSENSITIVITY; DRUG SAFETY; DRUG WITHDRAWAL; DYSPNEA; FATIGUE; FEMALE; FINGER SPAN TEST; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; NEUROLOGIC EXAMINATION; NEUROPSYCHOLOGICAL TEST; OUTCOME ASSESSMENT; OUTPATIENT CARE; PACED AUDITORY SERIAL ADDITION TEST; PAIN ASSESSMENT; PRURITUS; RATING SCALE; SCORING SYSTEM; SELF REPORT; TREATMENT DURATION; TREATMENT RESPONSE;

ADOLESCENT; ADULT; AGED; ANALGESICS, OPIOID; COGNITION; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; MORPHINE; NEUROPSYCHOLOGICAL TESTS; PAIN; PAIN MEASUREMENT; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 56849096729     PISSN: 15262375     EISSN: 15264637     Source Type: Journal    
DOI: 10.1111/j.1526-4637.2008.00483.x     Document Type: Article

References (44)

1. Turk DC, Monarch ES. Biopsychosocial perspective on chronic pain. In: Turk DC, Gatchel RJ, eds. Psychological Approaches to Pain Management. New York: The Guilford Press; 2002.
2. Von Korff M, Simon G. The relationship between pain and depression. Br J Psychiatry Suppl 1996; 168 (suppl 30): 101-8.
3. Caudill-Slosberg MA, Schwartz LM, Woloshin S. Office visits and analgesic prescriptions for musculoskeletal pain in US: 1980 vs. 2000. Pain 2004; 109: 514-9.
4. Gilson AM, Ryan KM, Joranson DE, Dahl JL. A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002. J Pain Symptom Manage 2004; 28: 176-88.
5. Joranson DE, Ryan KM, Gilson AM, Dahl JL. Trends in medical use and abuse of opioid analgesics. JAMA 2000; 283: 1710-4.
6. Clark MR, Treisman GJ, eds. Pain and depression. An interdisciplinary patient-centered approach. Adv Psychosom Med 2004; 25: 123-37.
7. Sjogren P, Thomsen AB, Olsen AK. Impaired neuropsychological performance in chronic nonmalignant pain patients receiving long-term oral opioid therapy. J Pain Symptom Manage 2000; 19: 100-8.
8. Sjogren P, Christrup LL, Petersen MA, Hojsted J. Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. Eur J Pain 2005; 9: 453-62.
9. Moulin DE, Iezzi A, Amireh R, et al. Randomized trial of oral morphine for chronic non-cancer pain. Lancet 1996; 347: 143-7.
10. Haythornthwaite JA, Menefee LA, Lynette MA, Quatrano-Piacentini Al, Pappagallo M. Outcome of chronic opioid therapy for non-cancer pain. J Pain Symptom Manage 1998; 15: 185-94.
11. Jamison RN, Schein JR, Vallow S, et al. Neuropsychological effects of long-term opioid use in chronic pain patients. J Pain Symptom Manage 2003; 26: 913-21.
12. Lorenz J, Beck H, Bromm B. Cognitive performance, mood and experimental pain before and during morphine-induced analgesia in patients with chronic non-malignant pain. Pain 1997; 73: 369-75.
13. Tassain V, Attal N, Fletcher D, et al. Long term effects of oral sustained release morphine on neuropsychological performance in patients with chronic non-cancer pain. Pain 2003; 104: 389-400.
14. Rowbotham MC, Twilling L, Davies PS, etal. Oral opioid therapy for chronic peripheral and central neuropathic pain. N Engl J Med 2003; 348: 1223-32.
15. Menefee LA, Frank ED, Crerand C, et al. The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions. Pain Med 2004; 5: 42-9.
16. Rosenthal MH, Bryant S, Iwan T, et al. Significant improvements in neurocognition observed in once-a-day AVINZA® (extended-release morphine sulfate)-treated patients with chronic moderate to severe osteoarthritis (OA) pain [abstract]. J Pain 2006; 7 (suppl 1): 67; abstract 865.
17. Jamison RN, Brocco TS, Parris WC. The influence of problems with concentration and memory on emotional distress and daily activities in chronic pain patients. Int J Psychiatry Med 1988; 18: 183-91.
18. Dufton BD. Cognitive failure and chronic pain. Int J Psychiatry Med 1989; 19: 291-7.
19. Kewman DG, Vaishampayan N, Zald D, Han B. Cognitive impairment in musculoskeletal patients. Int J Psychiatry Med 1991; 21: 253-62.
20. Schwartz DP, Barth JT, Dane JR, et al. Cognitive deficits in chronic pain patients with and without a history of head/neck injury: Development of a brief screening battery. Clin J Pain 1987; 3: 94-101.
21. Eccleston C. Chronic pain and attention: A cognitive approach. Br J Clin Psychol 1994; 22: 535-47.
22. Eccleston C. Chronic pain and distraction: An experimental investigation into the role of sustained and shifting attention in the processing of chronic persistent pain. Behav Res Ther 1995; 33: 391-405.
23. Eccleston C, Crombez G, Aldrich S, Stannard C. Attention and somatic awareness in chronic pain. Pain 1997; 72: 209-15.
24. Sletvold H, Stiles TC, Landro NI. Information processing in primary fibromyalgia, major depression, and healthy controls. J Rheumatol 1995; 22: 137-42.
25. McCracken LM, Iverson GL. Predicting complaints of impaired cognitive functioning in patients with chronic pain. J Pain Symptom Manage 2001; 5: 392-6.
26. Weiner DK, Rudy TE, Morrow L, Slaboda J, Lieber S. The relationship between pain, neuropsychological performance, and physical function in community-dwelling older adults with chronic low back pain. Pain Med 2006; 7: 60-70.
27. Rauck RL, Bookbinder SA, Bunker TR, et al. The ACTION study: A randomized, open-label multicenter trial comparing once-a-day morphine sulfate extended-release capsules (AVINZA) vs. twice-a-day oxycodone hydrochloride controlled-release tablets (OxyContin) for the treatment of chronic moderate to severe low back pain. J Opioid Manag 2006; 2: 155-66.
28. Caldwell JR, Rapoport RJ, Davis JC, et al. Efficacy and safety of a once-daily morphine formulation in chronic, moderate-to-severe osteoarthritis pain: Results from a randomized, placebo-controlled, double-blind trial and an open-label extension trial. J Pain Symptom Manage 2002; 23: 278-91.
29. Douglas MD, Garland WT, Kelly JB, et al. Efficacy of a new, once-daily, rapid-onset, extended-release morphine formulation (Morphelen™ ROER™) and a twice-daily morphine sulfate controlled-release formulation (MS Contin®) in patients with chronic, moderate-to-severe pain [abstract]. Presented at American Pain Society 20th Annual Scientific Meeting; Phoenix, AZ; April 19-22, 2001. Abstract 780.
30. Richards D, Simmonds M, Shelby S. Once daily, rapid onset, extended release morphine in patients with chronic malignant pain [abstract]. Presented at American Society of Clinical Oncology 37th Annual Meeting; San Francisco, CA; May 12-15, 2001. Abstract 1559.
31. Adams E, Chwieko P, Guary J, Ghalie R, de Jong E. Pain control in chronic non-cancer pain patients treated with once-a-day AVINZA® (morphine sulfate extended-release capsules) [abstract]. J Pain 2006; 7 (suppl 1): 57; abstract 825.
32. Wade JB, Hart RP. Attention and the stages of pain processing. Pain Med 2002; 3: 30-8.
33. Seymour RA, Simpson JM, Charlton JE, Phillips ME. An evaluation of length and end-phrase of visual analogue scales in dental pain. Pain 1985; 21 (2): 177-85.
34. Heaton RK, Getto CJ, Lehman RA, et al. A standardized evaluation of psychosocial factors in chronic pain. Pain 1982; 12 (2): 165-74.
35. Beck AT, Steer RA, Ball R, Ranieri W. Comparison of Beck Depression Inventories-IA and II in psychiatric outpatients. J Pers Assess 1996; 67 (3): 588-97.
36. Morley S, Williams AC, Black S. A confirmatory factor analysis of the Beck Depression Inventory in chronic pain. Pain 2002; 99 (1-2): 289-98.
37. Lezak MD. Neuropsychological Assessment, 2nd edition. New York: Oxford University Press; 1983.
38. Spreen O, Strauss E. A Compendium of Neuropsychological Tests: Administration, Norms and Commentary, 2nd edition. New York: Oxford University Press; 1998.
39. Tabachnick BG, Fidel LS. Using Multivariate Statistics, 3rd edition. New York: HarperCollins College Publishers; 1996.
40. Streiner DL. Regression toward the mean: Its etiology, diagnosis, and treatment. Can J Psychiatry 2001; 46: 72-7.
41. Arkinstall W, Sandler A, Goughnour B, et al. Efficacy of controlled-release codeine in chronic non-malignant pain: A randomized, placebo-controlled clinical trial. Pain 1995; 62: 169-78.
42. Matsumoto AK, Babul N, Ahdieh H. Oxymorphone extended-release tablets relieve moderate to severe pain and improve physical function in osteoarthritis: Results of a randomized, double-blind, placebo- and active-controlled phase III trial. Pain Med 2005; 6: 357-66.
43. Roth SH, Fleisschmann RM, Burch FX, etal. Around-the-clock controlled-release oxycodone therapy for osteoarthritis-related pain: Placebo-controlled trial and long-term evaluation. Arch Intern Med 2000; 160: 853-60.
44. Raja SN, Haythornthwaite JA, Pappagallo M, et al. Opioids versus antidepressants in postherpetic neuralgia: A randomized, placebo-controlled trial. Neurology 2002; 59: 1015-21.