Oral opioid therapy for chronic peripheral and central neuropathic pain

New England Journal of Medicine

Volumn 348, Issue 13, 2003, Pages 1223-1232

  Rowbotham, Michael C ^a,c   Twilling, Lisa ^a   Davies, Pamela S ^a   Reisner, Lori ^a,b   Taylor, Kirk ^a   Mohr, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Department of Neurology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEVORPHANOL; MU OPIATE RECEPTOR AGONIST; OPIATE;

ADULT; AGED; ANALGESIA; ANGER; ARTICLE; CHRONIC PAIN; CLINICAL TRIAL; COGNITION; CONFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DISTRESS SYNDROME; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG POTENCY; DRUNKENNESS; FEMALE; HUMAN; IRRITABILITY; MAJOR CLINICAL STUDY; MALE; MOOD DISORDER; MUSCLE WEAKNESS; NEUROPATHIC PAIN; PAIN ASSESSMENT; PERIPHERAL NEUROPATHY; PERSONALITY DISORDER; PRIORITY JOURNAL; PRURITUS; PSYCHOLOGIC ASSESSMENT; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; SIDE EFFECT; SLEEP; SOMNOLENCE; STROKE; SUICIDAL BEHAVIOR; SWEAT GLAND DISEASE; TREATMENT OUTCOME; VERTIGO; XEROSTOMIA;

ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CENTRAL NERVOUS SYSTEM DISEASES; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG TOLERANCE; FEMALE; HUMANS; LEVORPHANOL; MALE; MIDDLE AGED; NEURALGIA; OUTCOME ASSESSMENT (HEALTH CARE); PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 0037468691     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa021420     Document Type: Article

References (38)

1. Dubner R. A call for more science, not more rhetoric, regarding opioids and neuropathic pain. Pain 1991;47:1-2.
2. Fields HL. Can opiates relieve neuropathic pain? Pain 1988;35:365-7.
3. Amer S, Meyerson BA. Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 1988;33:11-23.
4. Idem. Genuine resistance to opioids - fact or fiction? Pain 1991;47:116-21.
5. Dellemijn P. Are opioids effective in relieving neuropathic pain? Pain 1999;80:453-62.
6. McQuay HJ. Opioid use in chronic pain. Acta Anaesthesiol Scand 1997;41:175-83.
7. Wall PD. Neuropathic pain. Pain 1990;43:267-8.
8. Portenoy RK, Foley KM, Inturrisi CE. The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions. Pain 1990;43:273-86.
9. Rowbotham MC, Reisner-Keller LA, Fields HL. Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia. Neurology 1991;41:1024-8.
10. Dellemijn PL, Vanneste JA. Randomized double-blind active-placebo-controlled crossover trial of intravenous fentanyl in neuropathic pain. Lancet 1997;349:753-8.
11. Rowbotham MC. The debate over opioids and neuropathic pain. In: Kalso E, Wiesenfeld-Hallin Z, McQuay HJ, eds. Opioid sensitivity of chronic noncancer pain. Vol. 14 of Progress in pain research and management. Seattle: IASP Press, 1999:307-18.
12. Watson CP, Babul N. Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia. Neurology 1998;50:1837-41.
13. Raja SN, Haythornthwaite JA, Pappagallo M, et al. Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology 2002;59:1015-21.
14. Morgan D, Cook CD, Smith MA, Picker MJ. An examination of the interactions between the antinociceptive effects ofmorphine and various mu-opioids: the role of intrinsic efficacy and stimulus intensity. Anesth Analg 1999;88:407-13.
15. Dixon R, Crews T, Inturrisi C, Foley K. Levorphanol: pharmacokinetics and steady-state plasma concentrations in patients with pain. Res Commun Chem Pathol Pharmacol 1983;41:3-17.
16. Morrison JD, Loan WB, Dundee JW. Controlled comparison of the efficacy of fourteen preparations in the relief of postoperative pain. Br Med J 1971;3:287-90.
17. Banister EH. Six potent analgesic drugs: a double-blind study in post-operative pain. Anaesthesia 1974;29:158-62.
18. First MB, Gibbon M, Spitzer RL, Williams JBW. Structured Clinical Interview for DSM-IV-TK. New York: New York State Psychiatric Institute, 1995. (Also available at http://cpmcnet.columbia.edu/dept/scid/.)
19. Max MB, Culnane M, Schafer SC, et al. Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood. Neurology 1987;37:589-96.
20. McNair DM, Lorr M, Droppleman LF. Manual for the Profile of Mood States (POMS). San Diego, Calif.: Educational and Industrial Testing Service, 1971.
21. Kerns RD, Turk DC, Rudy TE. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Pain 1985;23:345-56. (Also available at http://195.101.204.50:443/public/WHYMPI.html.)
22. Smith A. Symbol-Digit Modalities Test. Los Angeles: Westem Psychological Services, 1991. (Also available at http://www.tvtc.com:8080/tvtc/tvtcpage/sdmt.html.)
23. Preston KL, Bigelow GE, Liebson IA. Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts. J Pharmacol Exp Ther 1987;240:900-10.
24. Everhart ET, Shwonek P, Jacob P III, Rowbotham MC, Jones RT. Quantitation of levorphanol in human plasma at subnanogram per milliliter levels using capillary gas chromatography with electron-capture detection. J Chromatogr B Biomed Sci Appl 1999;729:173-81.
25. Littell RC, Pendergast J, Natarajan R. Modelling covariance structure in the analysis of repeated measures data. Stat Med 2000;19:1793-819.
26. Gilson AM, Joranson DE. Controlled substances and pain management: changes in knowledge and attitudes of state medical regulators. J Pain Symptom Manage 2001;21:227-37.
27. Joranson DE. Federal and state regulation of opioids. J Pain Symptom Manage 1990;5:Suppl:S12-S23.
28. Joranson DE, Gilson AM. Regulatory barriers to pain management. Semin Oncol Nuts 1998;14:158-63.
29. Maruta T, Swanson DW, Finlayson RE. Drug abuse and dependency in patients with chronic pain. Mayo Clin Proc 1979;54:241-4.
30. France RD, Urban BJ, Keefe FJ. Long-term use of narcotic analgesics in chronic pain. Soc Sci Med 1984;19:1379-82.
31. Dellemijn PL, van Duijn H, Vanneste JA. Prolonged treatment with transdermal fentanyl in neuropathic pain. J Pain Symptom Manage 1998;16:220-9.
32. Porter J, Jick H. Addiction rare in patients treated with narcotics. N Engl J Med 1980;302:123.
33. Watson CP, Evans RJ, Watt VR, Birkett N. Post-herpetic neuralgia: 208 cases. Pain 1988;35:289-97.
34. Moulin DE, Iezzi A, Amireh R, Sharpe WK, Boyd D, Merskey H. Randomized trial of oral morphine for chronic non-cancer pain. Lancet 1996;347:143-7.
35. Rowbotham M, Harden N, Stacey B, Bernstein P, Magnus-Miller L. Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial. JAMA 1998;280:1837-42.
36. Kishore-Kumar R, Max MB, Schafer SC, et al. Desipramine relieves postherpetic neuralgia. Clin Pharmacol Ther 1990;47:305-12.
37. Max MB, Schafer SC, Culnane M, Smollet B, Dubner R, Gracely RH. Amitriptyline, but not lorazepam, relieves postherpetic neuralgia. Neurology 1988;38:1427-32.
38. Max MB, Lynch SA, Muir J, Shoaf SE, Smoller B, Dubner R. Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. N Engl J Med 1992;326:1250-6.