Development of SLN and NLC enriched hydrogels for transdermal delivery of nitrendipine: In vitro and in vivo characteristics

Drug Development and Industrial Pharmacy

Volumn 35, Issue 1, 2009, Pages 98-113

  Bhaskar, Kesavan ^a,b   Krishna Mohan, Chinnala ^a   Lingam, Meka ^a   Jagan Mohan, Somagoni ^a   Venkateswarlu, Vobalaboina ^a   Madhusudan Rao, Yamsani ^a   Anbu, Jayaraman ^b   Ravichandran, Velayudam ^b  

^a KAKATIYA UNIVERSITY   (India)

^b VELS INSTITUTE OF SCIENCE   (India)

Author keywords

Antihypertensive; Hydrogel; Nanostructured lipid carrier; Nitrendipine; Solid lipid nanoparticles; Transdermal delivery

Indexed keywords

CARBOMER; CARBOPOL 934; CHITOSAN; DRUG CARRIER; EPIKURON 200; GLYCEROL; HYDROXYPROPYLCELLULOSE; MYRISTIC ACID DERIVATIVE; NANOSTRUCTURED LIPID CARRIER; NITRENDIPINE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; SURFACTANT; TRIMYRISTIN; UNCLASSIFIED DRUG; XANTHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; AREA UNDER THE CURVE; ARTICLE; DISEASE MODEL; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG HALF LIFE; DRUG PENETRATION; HYDROGEL; HYPERTENSION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; RAT; SKIN IRRITATION; SUSTAINED DRUG RELEASE; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRASOUND; ZETA POTENTIAL;

ADMINISTRATION, CUTANEOUS; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG STABILITY; DRUG STORAGE; HYPERTENSION; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NITRENDIPINE; PARTICLE SIZE; RATS; RATS, WISTAR; SKIN ABSORPTION; TRIGLYCERIDES;

EID: 56749105731     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802192822     Document Type: Article

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