Effect of insoluble fibre on intestinal morphology and mRNA expression pattern of inflammatory, cell cycle and growth marker genes in a piglet model

Archives of Animal Nutrition

Volumn 62, Issue 6, 2008, Pages 427-438

  Schedle, Karl ^a   Pfaffl, Michael W ^b   Plitzner, Christian ^a   Meyer, Heinrich H D ^b   Windisch, Wilhelm ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Animal model; Cluster analysis; Dietary fibre; Gene expression; Morphology

Indexed keywords

LIGNIN; MESSENGER RNA;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; CLUSTER ANALYSIS; DIETARY FIBER; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; INTESTINE MUCOSA; MALE; METABOLISM; NEWBORN; RANDOMIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLUBILITY; SWINE; WEANING;

ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; ANIMALS, NEWBORN; CLUSTER ANALYSIS; DIETARY FIBER; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; INTESTINAL MUCOSA; LIGNIN; MALE; RANDOM ALLOCATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOLUBILITY; SWINE; WEANING;

ANIMALIA; PINUS MASSONIANA; TRITICUM AESTIVUM;

EID: 56649119186     PISSN: 1745039X     EISSN: 14772817     Source Type: Journal    
DOI: 10.1080/17450390802479349     Document Type: Article

References (28)

1. American Association of Cereal Chemists. 2001. The definition of dietary fiber. Cereal Foods World. 46:112-129.
2. AOAC. 2000. Methods 985.29. Official methods of analysis. 17th ed. Gaithersburg (MD): W Horwitz.
3. Baker DH. 2008. Animal models in nutrition research. J Nutr. 138:391-396.
4. Bansal M, Belcastro V, Ambesi-Impiombato A, di Bernardo D. 2007. How to infer gene networks from expression profiles. Mol Syst Biol. 3:78.
5. Bravo L, Abia R, Saura-Calixto F. 1994. Polyphenols as dietary fiber associated compounds. Comparative study on in vivo and in vitro properties. J Agric Food Chem. 42:1481-1487.
6. Cooper DA, Berry DA, Spendel VA, Kiorpes AL, Peters JC, Middleton SJ. 1997. The domestic pig as a model for evaluating olestra's nutritional effects. J Nutr. 127:1555S-1565.
7. D'Haeseleer P. 2005. How does gene expression clustering work? Nat Biotechnol. 23:1499-1501.
8. Fleige S, Pfaffl MW. 2006. RNA integrity and the effect on the real-time qRT-PCR performance. Mol Asp Med. 27:126-139.
9. Fleige S, Preißinger W, Meyer HHD, Pfaffl MW. 2007. Effect of lactulose on growth performance and intestinal morphology of pre-ruminant calves using a milk replacer containing Enterococcus faecium. Animal. 1:367-373.
10. Fleige S, Walf V, Huch S, Prgomet C, Sehm J, Pfaffl MW. 2006. Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR. Biotechnol Lett. 28:1601-1613.
11. Hansen I, Knudsen KE, Eggum BO. 1992. Gastrointestinal implications in the rat of wheat bran, oat bran and pea fibre. Brit J Nutr. 68:451-462.
12. Hansen MJ, Chwalibog A, Tauson AH, Sawosz E. 2006. Influence of different fibre sources on digestibility and nitrogen and energy balances in growing pigs. Arch Anim Nutr. 60:390-401.
13. Hedemann MS, Højsgaard S, Jensen BB. 2003. Small intestinal morphology and activity of intestinal peptidases in piglets around weaning. J Anim Physiol Anim Nutr. 87:32-41.
14. Kubista M, Andrade JM, Bengtsson M, Forootan A, Jonak J, Lind K, Sindelka R, Sjoback R, Sjogreen B, Strombom L, Stahlberg A, Zoric N. 2006. The real-time polymerase chain reaction. Mol Aspects Med. 27:95-125.
15. Langhout DJ, Schutte JB, de Jong J, Sloetjes H, Verstegen MW, Tamminga S. 2000. Effect of viscosity on digestion of nutrients in conventional and germ-free chicks. Brit J Nutr. 83:533-540.
16. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-Delta Delta CT Method. Methods. 25:402-408.
17. Marion J, Biernat M, Thomas F, Savary G, Le Breton Y, Zabielski R, Le Huerou-Luron I, Le Dividich J. 2002. Small intestine growth and morphometry in piglets weaned at 7 days of age. Effects of level of energy intake. Reprod Nutr Dev. 42:339-354.
18. McDonald DE, Pethick DW, Mullan BP, Hampson DJ. 2001. Increasing viscosity of the intestinal contents alters small intestinal structure and intestinal growth, and stimulates proliferation of enterotoxigenic Escherichia coli in newly-weaned pigs. Brit J Nutr. 86:487-498.
19. Mitchell AD. 2007. Impact of research with cattle, pigs, and sheep on nutritional concepts: body composition and growth. J Nutr. 137:711-714.
20. Montagne L, Pluske JR, Hampson DJ. 2003. A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals. Anim Feed Sci Technol. 108:95-117.
21. Motta Ferreira W, Fraga MJ, Carabano R. 1996. Inclusion of grape pomace, in substitution for alfalfa hay, in diets for growing rabbits. Anim Sci. 63:167-174.
22. Pluske JR, Hampson DJ, Williams IH. 1997. Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livest Prod Sci. 51:215-236.
23. Schedle K, Plitzner C, Zhao L, Ettle T, Domig K, Windisch W. 2008. Effects of different insoluble dietary fibers, on performance, digestibility, and gut microbiology in piglets. Arch Anim Nutr. 62:141-151.
24. Sehm J, Lindermayer H, Meyer HHD, Pfaffl MW. 2006. The influence of apple- and red-wine pomace rich diet on mRNA expression of inflammatory and apoptotic markers in different piglet organs. Animal Sci. 82:877-887.
25. Sjögren K, Jansson JO, Isaksson OGP, Ohlsson C. 2002. A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liverderived IGF-I. Endocrine. 19:249-256.
26. Spurlock ME, Gabler NK. 2008. The development of porcine models of obesity and the metabolic syndrome. J Nutr. 138:397-402.
27. Wenk C. 2001. The role of dietary fibre in the digestive physiology of the pig. Anim Feed Sci Technol. 90:21-33.
28. Zhao L, Windisch W, Roth FX, Eder K, Ettle T. 2007. Nutritive value of Masson Pine pollen in comparison to wheat bran and effects on stool characteristics in a pig model. Bodenkultur. 58:29-38.