Quantitative assessment of TRPM5-dependent oral aversiveness of pharmaceuticals using a mouse brief-access taste aversion assay

Behavioural Pharmacology

Volumn 19, Issue 7, 2008, Pages 673-682

  Devantier, Heather R ^a   Long, Daniel J ^a   Brennan, Francis X ^a   Carlucci, Stacy A ^a   Hendrix, Cynthia ^a   Bryant, Robert W ^a   Salemme, F Raymond ^a   Palmer, R Kyle ^a  

^a Redpoint Bio Corporation   (United States)

Author keywords

Brief assay; Mouse; Pharmaceuticals; Taste; TRPM5

Indexed keywords

CAPSAICIN; CETIRIZINE; CIMETIDINE; CIPROFLOXACIN; CLARITHROMYCIN; CYCLOHEXIMIDE; DEXTROMETHORPHAN; DIPHENHYDRAMINE; LEVOFLOXACIN; METRONIDAZOLE; MOXIFLOXACIN; NICOTINE; PARACETAMOL; QUININE; SUMATRIPTAN SUCCINATE; TOPIRAMATE; VALPROIC ACID; VARDENAFIL;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BITTER TASTE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LICKING; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; PALATABILITY; QUANTITATIVE ANALYSIS; TASTE AVERSION; WATER DEPRIVATION;

ANIMALS; AVOIDANCE LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRINKING BEHAVIOR; FEMALE; GENE EXPRESSION; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NONPRESCRIPTION DRUGS; PRESCRIPTION DRUGS; SPECIES SPECIFICITY; TASTE; TASTE THRESHOLD; TRPM CATION CHANNELS;

EID: 56649115984     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3283123cd6     Document Type: Article

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