Spontaneously immortalized mouse mesothelial cells display characteristics of malignant transformation

Cell Proliferation

Volumn 41, Issue 6, 2008, Pages 894-908

  Sherwood, A L ^b,c   Mutsaers, S E ^b,d,e   Peeva, V K ^f   Robinson, C ^b,c   DeSilva, C J ^f   Swanson, N R ^c,f   Lake, R A ^a,b,c  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d Lung Institute of Western Australia   (Australia)

^e PATHWEST LABORATORY MEDICINE   (Australia)

^f Lotterywest State Microarray Facility   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANCHORAGE INDEPENDENT GROWTH; ANEUPLOIDY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL IMMORTALIZATION; CELL LINE; CELL POPULATION; CELL PROLIFERATION; FEMALE; GENE EXPRESSION; IN VITRO STUDY; INDUCED MUTATION; ISOGRAFT; LIFESPAN; MALIGNANT TRANSFORMATION; MESOTHELIUM CELL; MOUSE; NONHUMAN; PLEURA MESOTHELIOMA;

ANIMALS; CELL AGING; CELL LINE, TRANSFORMED; CELL SHAPE; CELL TRANSFORMATION, NEOPLASTIC; DNA; DOWN-REGULATION; EPITHELIAL CELLS; GENE DELETION; GENE EXPRESSION PROFILING; GENES, TUMOR SUPPRESSOR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESOTHELIOMA; MICE; MICE, INBRED C57BL;

MUS;

EID: 56549103993     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2008.00560.x     Document Type: Article

References (29)

1. Bot J, Whitaker D, Vivian J, Lake RA, Yao V, McCauley R (2003) Culturing mouse peritoneal mesothelial cells. Pathol. Res. Pract. 199, 341 344.
2. Cahill DP, Kinzler KW, Vogelstein B, Lengauer C (1999) Genetic instability and darwinian selection in tumours. Trends Cell Biol. 9, M57 M60.
3. Davis T, Kipling D (2005) Telomeres and telomerase biology in vertebrates: progress towards a non-human model for replicative senescence and ageing. Biogerontology 6, 371 385.
4. Davis MR, Manning LS, Whitaker D, Garlepp MJ, Robinson BW (1992) Establishment of a murine model of malignant mesothelioma. Int. J. Cancer 52, 881 886.
5. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocke M, Campisi J (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92, 9363 9367.
6. Ehmann UK, Osborn RC, Guzman RC, Fajardo LF (1991) Cultured proliferating rat mammary epithelial cells. In Vitro Cell. Dev. Biol. 27A, 749 754.
7. Funaki K, Everitt J, Bermudez E, Walker C (1991) Trisomy of rat chromosome 1 associated with mesothelial cell transformation. Cancer Res. 51, 4059 4066.
8. Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R (2005) Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am. J. Pathol. 166, 1827 1840.
9. Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100, 57 70.
10. Huggett AC, Ellis PA, Ford CP, Hampton LL, Rimoldi D, Thorgeirsson SS (1991) Development of resistance to the growth inhibitory effects of transforming growth factor beta 1 during the spontaneous transformation of rat liver epithelial cells. Cancer Res. 51, 5929 5936.
11. Illei PB, Rusch VW, Zakowski MF, Ladanyi M (2003) Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas. Clin. Cancer Res. 9, 2108 2113.
12. Kaighn ME, Camalier RF, Bertolero F, Saffiotti U (1988) Spontaneous establishment and characterization of mouse keratinocyte cell lines in serum-free medium. In Vitro Cell. Dev. Biol. 24, 845 854.
13. Ke Y, Reddel RR, Gerwin BI, Reddel HK, Somers AN, McMenamin MG, Laveck MA, Stahel RA, Lechner JF, Harris CC (1989) Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma. Am. J. Pathol. 134, 979 991.
14. Kittrell FS, Oborn CJ, Medina D (1992) Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro. Cancer Res. 52, 1924 1932.
15. Kravchenko IV, Furalyov VA, Vasylieva LA, Pylev LN (1998) Spontaneous and asbestos-induced transformation of mesothelial cells in vitro. Teratog. Carcinog. Mutagen. 18, 141 151.
16. Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J (2001) Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl. Acad. Sci. USA 98, 12072 12077.
17. Murthy SS, Testa JR (1999) Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma. J. Cell. Physiol. 180, 150 157.
18. Mutsaers SE (2004) The mesothelial cell. Int. J. Biochem. Cell Biol. 36, 9 16.
19. Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE (2001) Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev. 15, 398 403.
20. Reddel RR, Malan-Shibley L, Gerwin BI, Metcalf RA, Harris CC (1989) Tumorigenicity of human mesothelial cell line transfected with EJ-ras oncogene. J. Natl. Cancer Inst. 81, 945 948.
21. Robinson BW, Lake RA (2005) Advances in malignant mesothelioma. N. Engl. J. Med. 353, 1591 1603.
22. Robinson BW, Musk AW, Lake RA (2005) Malignant Mesothelioma. Lancet 366, 397 408.
23. Sedivy JM (1998) Can ends justify the means? telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells. Proc. Natl. Acad. Sci. USA 95, 9078 9081.
24. Sherr CJ, Depinho RA (2000) Cellular senescence: mitotic clock or culture shock? Cell 102, 407 410.
25. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545 15550.
26. Suda Y, Suzuki M, Ikawa Y, Aizawa S (1987) Mouse embryonic stem cells exhibit indefinite proliferative potential. J. Cell. Physiol. 133, 197 201.
27. Todaro GJ, Green H (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17, 299 313.
28. Wilson CM, Gatewood JW, McCormack JM, Walker WS (1991) Immortalization of growth factor-dependent mouse splenic macrophages derived from cloned progenitors. J. Immunol. Methods 137, 17 25.
29. Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW (2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445, 656 660.