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Volumn 35, Issue 11, 2008, Pages 2179-2186

Functional polymorphisms of folate-metabolizing enzymes in relation to homocysteine concentrations in systemic lupus erythematosus

Author keywords

Atherosclerosis; Coronary artery calcification; Genetic polymorphisms; Homocysteine; Systemic lupus erythematosus

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; CYSTATHIONINE BETA SYNTHASE; DIHYDROFOLATE REDUCTASE; FOLIC ACID; HOMOCYSTEINE; METHIONINE SYNTHASE; METHIONINE SYNTHASE REDUCTASE; PYRIDOXINE; THYMIDYLATE SYNTHASE;

EID: 56449130924     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.080071     Document Type: Article
Times cited : (19)

References (34)
  • 1
    • 34250621035 scopus 로고    scopus 로고
    • What can epidemiology tell us about systemic lupus erythematosus?
    • Simard JF, Costenbader KH. What can epidemiology tell us about systemic lupus erythematosus? Int J Clin Pract 2007;61:1170-80.
    • (2007) Int J Clin Pract , vol.61 , pp. 1170-1180
    • Simard, J.F.1    Costenbader, K.H.2
  • 2
    • 0031052874 scopus 로고    scopus 로고
    • Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: Comparison with the Framingham Study
    • Manzi S, Meilahn EN, Rairie JE, et al. Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study. Am J Epidemiol 1997;145:408-15.
    • (1997) Am J Epidemiol , vol.145 , pp. 408-415
    • Manzi, S.1    Meilahn, E.N.2    Rairie, J.E.3
  • 3
    • 20444373191 scopus 로고    scopus 로고
    • Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: The St. Francis Heart Study
    • Arad Y, Goodman KJ, Roth M, Newstein D, Guerci AD. Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study. J Am Coll Cardiol 2005;46:158-65.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 158-165
    • Arad, Y.1    Goodman, K.J.2    Roth, M.3    Newstein, D.4    Guerci, A.D.5
  • 4
    • 1842331509 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project
    • Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA 1997;277:1775-81.
    • (1997) JAMA , vol.277 , pp. 1775-1781
    • Graham, I.M.1    Daly, L.E.2    Refsum, H.M.3
  • 5
    • 0033822422 scopus 로고    scopus 로고
    • Biological and environmental determinants of plasma homocysteine
    • Schneede J, Refsum H, Ueland PM. Biological and environmental determinants of plasma homocysteine. Semin Thromb Hemost 2000;26:263-79.
    • (2000) Semin Thromb Hemost , vol.26 , pp. 263-279
    • Schneede, J.1    Refsum, H.2    Ueland, P.M.3
  • 6
    • 0021894152 scopus 로고
    • The natural history of homocystinuria due to cystathionine beta-synthase deficiency
    • Mudd SH, Skovby F, Levy HL, et al. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet 1985;37:1-31.
    • (1985) Am J Hum Genet , vol.37 , pp. 1-31
    • Mudd, S.H.1    Skovby, F.2    Levy, H.L.3
  • 7
    • 0029738540 scopus 로고    scopus 로고
    • The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia
    • Harmon DL, Woodside JV, Yarnell JW, et al. The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. QJM 1996;89:571-7.
    • (1996) QJM , vol.89 , pp. 571-577
    • Harmon, D.L.1    Woodside, J.V.2    Yarnell, J.W.3
  • 8
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques PF, Bostom AG, Williams RR, et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996;93:7-9.
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 9
    • 33947239251 scopus 로고    scopus 로고
    • Functional inference of the methylenetetrahydrofolate reductase 677C > T and 1298A > C polymorphisms from a large-scale epidemiological study
    • Ulvik A, Ueland PM, Fredriksen A, et al. Functional inference of the methylenetetrahydrofolate reductase 677C > T and 1298A > C polymorphisms from a large-scale epidemiological study. Hum Genet 2007;121:57-64.
    • (2007) Hum Genet , vol.121 , pp. 57-64
    • Ulvik, A.1    Ueland, P.M.2    Fredriksen, A.3
  • 10
    • 0035159261 scopus 로고    scopus 로고
    • Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men
    • Dekou V, Gudnason V, Hawe E, Miller GJ, Stansbie D, Humphries SE. Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men. Thromb Haemost 2001;85:67-74.
    • (2001) Thromb Haemost , vol.85 , pp. 67-74
    • Dekou, V.1    Gudnason, V.2    Hawe, E.3    Miller, G.J.4    Stansbie, D.5    Humphries, S.E.6
  • 11
    • 0032713815 scopus 로고    scopus 로고
    • Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations
    • Harmon DL, Shields DC, Woodside JV, et al. Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol 1999;17:298-309.
    • (1999) Genet Epidemiol , vol.17 , pp. 298-309
    • Harmon, D.L.1    Shields, D.C.2    Woodside, J.V.3
  • 12
    • 34848881628 scopus 로고    scopus 로고
    • Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism
    • Fredriksen A, Meyer K, Ueland PM, Vollset SE, Grotmol T, Schneede J. Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism. Hum Mutat 2007;28:856-65.
    • (2007) Hum Mutat , vol.28 , pp. 856-865
    • Fredriksen, A.1    Meyer, K.2    Ueland, P.M.3    Vollset, S.E.4    Grotmol, T.5    Schneede, J.6
  • 13
    • 0034904708 scopus 로고    scopus 로고
    • The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations
    • Gaughan DJ, Kluijtmans LA, Barbaux S, et al. The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations. Atherosclerosis 2001;157:451-6.
    • (2001) Atherosclerosis , vol.157 , pp. 451-456
    • Gaughan, D.J.1    Kluijtmans, L.A.2    Barbaux, S.3
  • 14
    • 56449112095 scopus 로고    scopus 로고
    • Gaughan DJ, Kluijtmans LA, Barbaux S, et al. Corrigendum to The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations. [Atherosclerosis 2001;157:451-6]. Atherosclerosis 2002;167:373.
    • Gaughan DJ, Kluijtmans LA, Barbaux S, et al. Corrigendum to "The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations". [Atherosclerosis 2001;157:451-6]. Atherosclerosis 2002;167:373.
  • 15
    • 20244362795 scopus 로고    scopus 로고
    • A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations
    • Kealey C, Brown KS, Woodside JV, et al. A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations. Hum Genet 2005;116:347-53.
    • (2005) Hum Genet , vol.116 , pp. 347-353
    • Kealey, C.1    Brown, K.S.2    Woodside, J.V.3
  • 16
    • 33845531853 scopus 로고    scopus 로고
    • Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels
    • Gellekink H, Blom HJ, van der Linden IJ, den Heijer M. Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels. Eur J Hum Genet 2007;15:103-9.
    • (2007) Eur J Hum Genet , vol.15 , pp. 103-109
    • Gellekink, H.1    Blom, H.J.2    van der Linden, I.J.3    den Heijer, M.4
  • 17
    • 0242495176 scopus 로고    scopus 로고
    • Risk factors for coronary heart disease in women with systemic lupus erythematosus: The Toronto Risk Factor Study
    • Bruce IN, Urowitz MB, Gladman DD, Ibanez D, Steiner G. Risk factors for coronary heart disease in women with systemic lupus erythematosus: the Toronto Risk Factor Study. Arthritis Rheum 2003;48:3159-67.
    • (2003) Arthritis Rheum , vol.48 , pp. 3159-3167
    • Bruce, I.N.1    Urowitz, M.B.2    Gladman, D.D.3    Ibanez, D.4    Steiner, G.5
  • 18
    • 20444378185 scopus 로고    scopus 로고
    • Thrombosis in systemic lupus erythematosus: Congenital and acquired risk factors
    • Afeltra A, Vadacca M, Conti L, et al. Thrombosis in systemic lupus erythematosus: congenital and acquired risk factors. Arthritis Rheum 2005;53:452-9.
    • (2005) Arthritis Rheum , vol.53 , pp. 452-459
    • Afeltra, A.1    Vadacca, M.2    Conti, L.3
  • 19
    • 33745899637 scopus 로고    scopus 로고
    • Homocysteine levels and disease duration independently correlate with coronary artery calcification in patients with systemic lupus erythematosus
    • Von Feldt JM, Scalzi LV, Cucchiara AJ, et al. Homocysteine levels and disease duration independently correlate with coronary artery calcification in patients with systemic lupus erythematosus. Arthritis Rheum 2006;54:2220-7.
    • (2006) Arthritis Rheum , vol.54 , pp. 2220-2227
    • Von Feldt, J.M.1    Scalzi, L.V.2    Cucchiara, A.J.3
  • 20
    • 33645359743 scopus 로고    scopus 로고
    • Traditional risk factor assessment does not capture the extent of cardiovascular risk in systemic lupus erythematosus
    • Lee AB, Godfrey T, Rowley KG, et al. Traditional risk factor assessment does not capture the extent of cardiovascular risk in systemic lupus erythematosus. Intern Med J 2006;36:237-43.
    • (2006) Intern Med J , vol.36 , pp. 237-243
    • Lee, A.B.1    Godfrey, T.2    Rowley, K.G.3
  • 21
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]
    • Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 22
    • 34247326091 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1: Plasma concentrations and A(-2518)G promoter polymorphism of its gene in systemic lupus erythematosus
    • Brown KS, Nackos E, Morthala S, Jensen LE, Whitehead AS, Von Feldt JM. Monocyte chemoattractant protein-1: plasma concentrations and A(-2518)G promoter polymorphism of its gene in systemic lupus erythematosus. J Rheumatol 2007;34:740-6.
    • (2007) J Rheumatol , vol.34 , pp. 740-746
    • Brown, K.S.1    Nackos, E.2    Morthala, S.3    Jensen, L.E.4    Whitehead, A.S.5    Von Feldt, J.M.6
  • 23
    • 0037126526 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
    • National Cholesterol Education Program NCEP
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 24
    • 1642502319 scopus 로고    scopus 로고
    • National Kidney Foundation practice guidelines for chronic kidney disease: Evaluation, classification, and stratification
    • Levey AS, Coresh J, Balk E, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med 2003;139:137-47.
    • (2003) Ann Intern Med , vol.139 , pp. 137-147
    • Levey, A.S.1    Coresh, J.2    Balk, E.3
  • 25
    • 0033927120 scopus 로고    scopus 로고
    • Accurate and rapid "multiplex heteroduplexing" method for genotyping key enzymes involved in folate/homocysteine metabolism
    • Barbaux S, Kluijtmans LA, Whitehead AS. Accurate and rapid "multiplex heteroduplexing" method for genotyping key enzymes involved in folate/homocysteine metabolism. Clin Chem 2000;46:907-12.
    • (2000) Clin Chem , vol.46 , pp. 907-912
    • Barbaux, S.1    Kluijtmans, L.A.2    Whitehead, A.S.3
  • 26
    • 33644876453 scopus 로고    scopus 로고
    • SNP500Cancer: A public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes
    • Packer BR, Yeager M, Burdett L, et al. SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes. Nucl Acids Res 2006;34:D617-21.
    • (2006) Nucl Acids Res , vol.34
    • Packer, B.R.1    Yeager, M.2    Burdett, L.3
  • 27
    • 0942290719 scopus 로고    scopus 로고
    • New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?
    • Johnson WG, Stenroos ES, Spychala JR, Chatkupt S, Ming SX, Buyske S. New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy? Am J Med Genet A 2004;124:339-45.
    • (2004) Am J Med Genet A , vol.124 , pp. 339-345
    • Johnson, W.G.1    Stenroos, E.S.2    Spychala, J.R.3    Chatkupt, S.4    Ming, S.X.5    Buyske, S.6
  • 28
    • 0141893992 scopus 로고    scopus 로고
    • Shi M, Caprau D, Romitti P, Christensen K, Murray JC. Genotype frequencies and linkage disequilibrium in the CEPH human diversity panel for variants in folate pathway genes MTHFR, MTHFD, MTRR, RFC1, and GCP2. Birth Defects Res A Clin Mol Teratol 2003;67:545-9.
    • Shi M, Caprau D, Romitti P, Christensen K, Murray JC. Genotype frequencies and linkage disequilibrium in the CEPH human diversity panel for variants in folate pathway genes MTHFR, MTHFD, MTRR, RFC1, and GCP2. Birth Defects Res A Clin Mol Teratol 2003;67:545-9.
  • 29
    • 0033020324 scopus 로고    scopus 로고
    • World distribution of the T833C/844INS68 CBS in cis double mutation: A reliable anthropological marker
    • Pepe G, Vanegas OC, Rickards O, et al. World distribution of the T833C/844INS68 CBS in cis double mutation: a reliable anthropological marker. Hum Genet 1999;104:126-9.
    • (1999) Hum Genet , vol.104 , pp. 126-129
    • Pepe, G.1    Vanegas, O.C.2    Rickards, O.3
  • 30
    • 3543065129 scopus 로고    scopus 로고
    • Single nucleotide polymorphism profiling across the methotrexate pathway in normal subjects and patients with rheumatoid arthritis
    • Ranganathan P, Culverhouse R, Marsh S, et al. Single nucleotide polymorphism profiling across the methotrexate pathway in normal subjects and patients with rheumatoid arthritis. Pharmacogenomics 2004;5:559-69.
    • (2004) Pharmacogenomics , vol.5 , pp. 559-569
    • Ranganathan, P.1    Culverhouse, R.2    Marsh, S.3
  • 31
    • 0031787461 scopus 로고    scopus 로고
    • Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: A retrospective cohort study
    • Fijnheer R, Roest M, Haas FJ, De Groot PG, Derksen RH. Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study. J Rheumatol 1998;25:1737-42.
    • (1998) J Rheumatol , vol.25 , pp. 1737-1742
    • Fijnheer, R.1    Roest, M.2    Haas, F.J.3    De Groot, P.G.4    Derksen, R.H.5
  • 32
    • 34547220582 scopus 로고    scopus 로고
    • MTR 2756 A > G polymorphism is associated with the risk of systemic lupus erythematosus in the Polish population
    • Burzynski M, Duriagin S, Mostowska M, Wudarski M, Chwalinska-Sadowska H, Jagodzinski PP. MTR 2756 A > G polymorphism is associated with the risk of systemic lupus erythematosus in the Polish population. Lupus 2007;16:450-4.
    • (2007) Lupus , vol.16 , pp. 450-454
    • Burzynski, M.1    Duriagin, S.2    Mostowska, M.3    Wudarski, M.4    Chwalinska-Sadowska, H.5    Jagodzinski, P.P.6
  • 33
    • 3042844018 scopus 로고    scopus 로고
    • Association between serum homocysteine and markers of impaired kidney function in adults in the United States
    • Francis ME, Eggers PW, Hostetter TH, Briggs JP. Association between serum homocysteine and markers of impaired kidney function in adults in the United States. Kidney Int 2004;66:303-12.
    • (2004) Kidney Int , vol.66 , pp. 303-312
    • Francis, M.E.1    Eggers, P.W.2    Hostetter, T.H.3    Briggs, J.P.4
  • 34
    • 33745551531 scopus 로고    scopus 로고
    • The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels
    • Parle-McDermott A, Mills JL, Molloy AM, et al. The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels. Mol Genet Metab 2006;88:290-4.
    • (2006) Mol Genet Metab , vol.88 , pp. 290-294
    • Parle-McDermott, A.1    Mills, J.L.2    Molloy, A.M.3


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