The expression of ABCG4, V-ATPase and clinic significance of their correlation with NSCLC

Chinese Journal of Lung Cancer

Volumn 11, Issue 5, 2008, Pages 691-695

  Zhang, Zhipei ^a   Li, Xiaofei ^a   Wang, Xiaoping ^a   Zhou, Yong'an ^a   Xu, Hong ^a   Wang, Jian ^a   Huang, Lijun ^a   Tian, Yutu ^a   Cheng, Qingshu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

ABCG4 protein; Drug resistance; Lung neoplasma; V ATPase

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER G4; ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; V ADENOSINE TRIPHOSPHATASE;

ARTICLE; CELL MEMBRANE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DISEASE SEVERITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MICROSCOPY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR DIFFERENTIATION;

EID: 56449113406     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: 10.3779/j.issn.1009-3419.2008.05.023     Document Type: Article

References (11)

1. Li HB. The analysis of incidence rate and death rate about lung cancers from 2002 to 2004 in Pu Tuo district of Shang Hai. Shanghai Journal of Preventive Medicine, 2006, 18(2): 60-61.
2. Li CL, Hou M, Zhao Y, et al. Expression of multiple drug resistance-associated proteins in non-small cell lung cancer tissues and its clinical significance. Chin J Lung Cancer, 2005, 8(6): 523-526.
3. Huang Y, Sadee W. Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells. Cancer Lett, 2006, 239(2): 168-182.
4. Engel T, Lorkowski S, Lueken A, et al. The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages. Biochem Biophys Res Commun, 2001, 288(2): 483-488.
5. Albermann N, Schmitz-Winnenthal FH, graggen KZ, et al. Expre-ssion of the drug transporters MDR1/ABCB1, MRP1/ ABCC1, RP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononu-clear cells and their relationship with the expression in intestine and liver. Biochem Pharmcol, 2005, 70(6): 949-958.
6. Oldfield S, Lowry C, Ruddick J, et al. ABCG4: a novel human white family ABC-transporter expressed in the brain and eye. Biochem Biophys Acta, 2002, 159(1-3): 175-179.
7. Yoshikawa M, Yabuuchi H, Kuroiwa A, et al. Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4q. Gene, 2002, 293 (1-2): 67-75.
8. Fujiyoshi M, Ohtsuki S, Hori S, et al. 24S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression. J Neurochem, 2007, 100(4): 968-978.
9. Wang N, Lan D, Chen W, et al. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc Natl Acad Sci USA, 2004, 101(26): 9774-9779.
10. +-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity. Am J Physiol Cell Physiol, 2004, 286(6): C1443-C1452.
11. Breedveld P, Pluim D, Cipriani G, et al. The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models. Mol Pharmaco, 2007, 71(1): 240-249.