Expression of multiple drug resistance-associated proteins in non-small cell lung cancer tissues and its clinical significance

Chinese Journal of Lung Cancer

Volumn 8, Issue 6, 2005, Pages 523-526

  Li, Changlin ^a   Hou, Mei ^b   Zhao, Yu ^b   Zhou, Qinghua ^b  

^a SICHUAN UNIVERSITY   (China)

^b NONE

Author keywords

Glutathion S transferase ; Lung neoplasms; Lung resistance related protein; Multidrug resistance associated protein; P glycoprotein; Topoisomerase II

Indexed keywords

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); GLUTATHIONE TRANSFERASE P1; GLYCOPROTEIN P; LUNG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CHEMOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION;

EID: 33645092149     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Kreisholt J, Sorensen M, Jensen PB, et al. Immunohistochemical detection of DNA topoisomerase II alpha, P-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer. Br J Cancer, 1998, 77(9):1469-1473.
2. Tan B, Piwnica-Worms D, Ratner L. Multidrug resistance transporters and modulation. Curr Opin Oncol, 2000, 12(5):450-458.
3. Arai T, Yasuda Y, Takaya T, et al. Immunohistochemical expression of glutathione transferase-pi in untreated primary non-small-cell lung cancer. Cancer Detect Prev, 2000, 24(3):252-257.
4. Nishio K, Nakamura T, Koh Y, et al. Drug resistance in lung cancer. Curr Opin Oncol, 1999, 11(2):109-115.
5. Berger W, Elbling L, Hauptmann E, et al. Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells. Int J Cancer, 1997, 73 (1):84-93.
6. Scheper RJ, Broxterman HJ, Scheffer GL, et al. Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res, 1993, 53(7):1475-1479.
7. Chauncey TR. Drug resistance mechanisms in acute leukemia. Curr Opin Oncol, 2001, 13(1):21-26.
8. Oshika Y, Nakamura M, Tokunaga T, et al. Multidrug resistance-associated protein and mutant p53 protein expression in non-small cell lung cancer. Mod Pathol, 1998, 11(11):1059-1063.
9. Schroeijers AB, Scheffer GL, Reurs AW, et al. Detection of the Mr 110,000 lung resistance-related protein LRP/MVP with monoclonal antibodies. J Histochem Cytochem, 2001, 49(11):1379-1385.
10. Trussardi A, Poitevin G, Gorisse MC, et al. Sequential overexpression of LRP and MRP but not P-gp 170 in VP16-selected A549 adenocarcinoma cells. Int J Oncol, 1998, 13(3):543-548.
11. Nakanishi Y, Kawasaki M, Bai F, et al. Expression of p53 and glutathione S-transferase-pi relates to clinical drug resistance in non-small cell lung cancer. Oncology, 1999, 57(4):318-323.
12. Dingemans AC, van Ark-Otte J, Span S, et al. Topoisomerase II alpha and other drug resistance markers in advanced non-small cell lung cancer. Lung Cancer, 2001, 32(2):117-128.