Gram-negative resistance in Singapore: A historical perspective

Annals of the Academy of Medicine Singapore

Volumn 37, Issue 10, 2008, Pages 847-854

  Tse, Hsien Koh ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

AmpC; Carbapenemase; Extended spectrum lactamase; Oxacillinase; Quinolone

Indexed keywords

AMPICILLIN; BETA LACTAMASE AMPC; CARBAPENEM; CARBENICILLIN; CEFALORIDINE; CHLORAMPHENICOL; COTRIMOXAZOLE; DOXYCYCLINE; ERYTHROMYCIN; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; KANAMYCIN; METALLO BETA LACTAMASE; METICILLIN; NALIDIXIC ACID; NITROFURANTOIN; OXACILLIN; PENICILLIN G; POLYMYXIN B; QUINOLONE; STREPTOMYCIN; SULFONAMIDE; TETRACYCLINE;

ACINETOBACTER; ANTIBIOTIC RESISTANCE; ENTEROBACTERIACEAE; GRAM NEGATIVE BACTERIUM; NONHUMAN; PSEUDOMONAS AERUGINOSA; REVIEW; SINGAPORE;

EID: 56449108783     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Review

References (63)

1. Tay L. Microbiology in Singapore. Ann Acad Med Singapore 1989;18:465-76.
2. Tan RJS, Seto WH, Sng EH, Tay L, Wee R. Antimicrobial sensitivity testing of hospital isolates using a standardised disc method. Asian J Mod Med 1974;10:361-3.
3. Network for Antimicrobial Resistance Surveillance (Singapore). Singapore: NARSS Report, Feb 2007.
4. Kliebe C, Nies BA, Meyer JF, Tolxdorff-Neutzling RM, Wiedemann B. Evolution of plasmid-coded resistance to broad-spectrum cephalosporins. Antimicrob Agents Chemother 1985;28:302-7.
5. Bradford PA. Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev 2001;14:933-51.
6. Mulgrave L. Extended broad-spectrum beta-lactamases in Australia. Med J Aust 1990;152:444-5.
7. Howard C, van Daal A, Kelly G, Schooneveldt J, Nimmo G, Giffard PM. Identification and minisequencing-based discrimination of SHV beta-lactamases in nosocomial infection-associated Klebsiella pneumoniae in Brisbane, Australia. Antimicrob Agents Chemother 2002;46:659-64.
8. Inglis TJ, Kumarasinghe G, Chow C, Liew HY. Multiple antibiotic resistance in Klebsiella spp. and other Enterobacteriaceae isolated in Singapore. Singapore Med J 1994;35:602-4.
9. Annual Report. Singapore: Department of Pathology, Singapore General Hospital, 1982.
10. Kumarasinghe G, Chow C, Koh BL, Chiang KL, Liew HY, Ti TY. Antimicrobial resistance problem in a university hospital. Pathology 1995;27:67-70.
11. Kumarasinghe G, Chow C, Chiu C. In vitro activity of meropenem against organisms causing serious infections in a Singapore hospital. Int J Antimicrob Agents 1997;9:121-5.
12. Kumarasinghe G, Chow C, Tambyah PA. Widespread resistance to new antimicrobials in a university hospital before clinical use. Int J Antimicrob Agents 2001;18:391-3.
13. Chlebicki MP, Oh HM. Extended-spectrum beta-lactamases in clinical isolates of Escherichia coli and Klebsiella spp. in a Singapore hospital: clinical spectrum. Ann Acad Med Singapore 2004;33:302-6.
14. Hirakata Y, Matsuda J, Miyazaki Y, Kamihira S, Kawakami S, Miyazawa Y, et al. Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998-2002). Diagn Microbiol Infect Dis 2005;52:323-9.
15. Biedenbach DJ, Lewis MT, Jones RN. In vitro evaluation of cefepime and other broad-spectrum beta-lactams for isolates in Malaysia and Singapore medical centers. The Malaysia/Singapore Antimicrobial Resistance Study Group. Diagn Microbiol Infect Dis 1999;35:277-83.
16. Bell JM, Turnidge JD, Gales AC, Pfaller MA, Jones RN. Prevalence of extended spectrum beta-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998-99). Diagn Microbiol Infect Dis 2002;42:193-8.
17. Koh TH, Wang GC, Sng LH, Koh TY. CTX-M and plasmid-mediated AmpC-producing Enterobacteriaceae Singapore. Emerg Infect Dis 2004;10:1172-4.
18. Rodríguez MM, Power P, Radice M, Vay C, Famiglietti A, Galleni M, et al. Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases. Antimicrob Agents Chemother 2004;48:4895-7.
19. Olson AB, Silverman M, Boyd DA, McGeer A, Willey BM, Pong-Porter V, et al. Identification of a progenitor of the CTX-M-9 group of extended-spectrum beta-lactamases from Kluyvera georgiana isolated in Guyana. Antimicrob Agents Chemother 2005;49:2112-5.
20. Livermore DM, Canton R, Gniadkowski M, Nordmann P, Rossolini GM, Arlet G, et al. CTX-M: changing the face of ESBLs in Europe. J Antimicrob Chemother 2007;59:165-74.
21. Tan BH, Tan AL. Community-acquired bacteremia with an ESBL-producing Escherichia coli strain - a case report. Int J Infect Dis 2002;6:318-9.
22. Woodford N, Ward ME, Kaufmann ME, Turton J, Fagan EJ, James D, et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother 2004;54:735-43.
23. Coque TM, Novais A, Carattoli A, Poirel L, Pitout J, Peixe L, et al. Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15. Emerg Infect Dis 2008;14:195-200.
24. Woodford N, Dallow JW, Hill RL, Palepou MF, Pike R, Ward ME, et al. Ertapenem resistance among Klebsiella and Enterobacter submitted in the UK to a reference laboratory. Int J Antimicrob Agents 2007;29:456-9.
25. Bell JM, Turnidge JD, Jones RN. Prevalence of extended-spectrum beta-lactamase-producing Enterobacter cloacae in the Asia-Pacific region: Results from the SENTRY Antimicrobial Surveillance Program, 1998 to 2001. Antimicrob Agents Chemother 2003;47:3989-93.
26. Chiew YF. Detection of extended-spectrum beta-lactamases in a Singapore routine clinical microbiology laboratory. J Hosp Infect 2004;56:328-9.
27. Philippon A, Arlet G, Jacoby GA. Plasmid-determined AmpC-type beta-lactamases. Antimicrob Agents Chemother 2002;46:1-11.
28. Koh TH, Sng LH, Wang G, Hsu LY, Lin RT, Tee NW. Emerging problems with plasmid-mediated DHA and CMY AmpC beta-lactamases in Enterobacteriaceae in Singapore. Int J Antimicrob Agents 2007;30:278-80.
29. Tan TY, Ng SY, Teo L, Koh Y, Teok CH. Detection of plasmid-mediated AmpC in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis. J Clin Pathol 2008;61:642-4
30. Yong D, Lim Y, Song W, Choi YS, Park DY, Lee H, et al. Plasmid-mediated, inducible AmpC beta-lactamase (DHA-1)-producing Enterobacteriaceae at a Korean hospital: wide dissemination in Klebsiella pneumoniae and Klebsiella oxytoca and emergence in Proteus mirabilis. Diagn Microbiol Infect Dis 2005;53:65-70.
31. Yan JJ, Ko WC, Jung YC, Chuang CL, Wu JJ. Emergence of Klebsiella pneumoniae isolates producing inducible DHA-1 beta-lactamase in a university hospital in Taiwan. J Clin Microbiol 2002;40:3121-6.
32. Kurupati P, Tan KS, Kumarasinghe G, Poh CL. Inhibition of gene expression and growth by antisense peptide nucleic acids in a multiresistant beta-lacamase-producing Klebsiella pneumoniae strain. Antimicrob Agents Chemother 2007;51:805-11.
33. BSAC Methods for Antimicrobial Susceptibility Testing Version 7.1. British Society for Antimicrobial Chemotherapy; 2008. Available at: http://www.bsac.org.uk/_db/_documents/version_7_1_february_2008.pdf. Accessed 12 April 2008.
34. Lee K, Yong D, Choi YS, Yum JH, Kim JM, Woodford N, et al. Reduced imipenem susceptibility in Klebsiella pneumoniae clinical isolates with plasmid-mediated CMY-2 and DHA-1 beta-lactamases co-mediated by porin loss. Int J Antimicrob Agents 2007;29:201-6.
35. Winokur PL, Vonstein DL, Hoffman LJ, Uhlenhopp EK, Doern GV. Evidence for transfer of CMY-2 AmpC beta-lactamase plasmids between Escherichia coli and Salmonella isolates from food animals and humans. Antimicrob Agents Chemother 2001;45:2716-22.
36. Chaibi EB, Sirot D, Paul G, Labia R. Inhibitor-resistant TEM beta-lactamases: phenotypic, genetic and biochemical characteristics. J Antimicrob Chemother 1999;43:447-58.
37. Koh TH, Wang G, Koh T. High-level cefepime resistance in Escherichia coli from Singapore producing OXA-1 beta-lactamase. Int J Antimicrob Agents 2008;31:382-3.
38. Stokes HW, Hall RM. A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons. Mol Microbiol 1989 3:1669-83.
39. Walsh TR, Toleman MA, Poirel L, Nordmann P. Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev 2005;18:306-25.
40. Watanabe M, Iyobe S, Inoue M, Mitsuhashi S. Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 1991;35:147-51.
41. Koh TH, Babini GS, Woodford N, Sng LH, Hall LM, Livermore DM. Carbapenem-hydrolysing IMP-1 beta-lactamase in Klebsiella pneumoniae from Singapore. Lancet 1999;353:2162.
42. Koh TH, Sng LH, Babini GS, Woodford N, Livermore DM, Hall LM. Carbapenem-resistant Klebsiella pneumoniae in Singapore producing IMP-1 beta-lactamase and lacking an outer membrane protein. Antimicrob Agents Chemother 2001;45:1939-40.
43. Kurokawa H, Yagi T, Shibata N, Shibayama K, Arakawa Y. Worldwide proliferation of carbapenem-resistant gram-negative bacteria. Lancet 1999;354:955.
44. Gibb AP, Tribuddharat C, Moore RA, Louie TJ, Krulick W, Livermore DM, et al. Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new bla(IMP) allele, bla(IMP-7). Antimicrob Agents Chemother 2002;46:255-8.
45. Ho SE, Subramaniam G, Palasubramaniam S, Navaratnam P. Carbapenem-resistant Pseudomonas aeruginosa in Malaysia producing IMP-7 beta-lactamase. Antimicrob Agents Chemother 2002;46:3286-7.
46. Kouda S, Kuwahara R, Ohara M, Shigeta M, Fujiwara T, Komatsuzawa H, et al. First isolation of bla(IMP-7) in a Pseudomonas aeruginosa in Japan. J Infect Chemother. 2007;13:276-7.
47. Koh TH, Wang GC, Sng LH. IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore. Antimicrob Agents Chemother 2004;48:2334-6.
48. Ang SW, Lee ST. Emergence of a multiply-resistant strain of Acinetobacter in a burns unit. Ann Acad Med Singapore 1992;21:660-3.
49. Kuah BG, Kumarasinghe G, Doran J, Chang HR. Antimicrobial susceptibilities of clinical isolates of Acinetobacter baumannii from Singapore. Antimicrob Agents Chemother 1994;38:2502-3.
50. Sng LH, Yeo M. Changing trends in the antimicrobial susceptibility of clinical isolates of Acinetobacter baumannii. Ann Acad Med Singapore 1996;25:179-83.
51. Paton R, Miles R, Hood J, Amyes S. ARI 1: beta-lactamase-mediated imipenem resistance in Acinetobacter baumannii. Int J Antimicrob Agents 1993;2:81-8.
52. Afzal-Shah M, Woodford N, Livermore DM. Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii. Antimicrob Agents Chemother 2001;45:583-8.
53. Brown S, Amyes SG. The sequences of seven class D beta-lactamases isolated from carbapenem-resistant Acinetobacter baumannii from four continents. Clin Microbiol Infect 2005;11:326-9.
54. Walther-Rasmussen J, Høiby N. OXA-type carbapenemases. J Antimicrob Chemother 2006;57:373-83.
55. Koh TH, Sng LH, Wang GC, Hsu LY, Zhao Y. IMP-4 and OXA beta-lactamases in Acinetobacter baumannii from Singapore. J Antimicrob Chemother 2007;59:627-32.
56. Chu YW, Afzal-Shah M, Houang ET, Palepou MI, Lyon DJ, Woodford N, et al. IMP-4, a novel metallo-beta-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998. Antimicrob Agents Chemother 2001;45:710-4.
57. Thomas L, Espedido B, Watson S, Iredell J. Forewarned is forearmed: antibiotic resistance gene surveillance in critical care. J Hosp Infect 2005;60:291-3.
58. Tan TY, Ng LS. Susceptibility of multi-resistant gram-negative bacilli in Singapore to tigecycline as tested by agar dilution. Ann Acad Med Singapore 2007;36:807-10.
59. National Antimicrobial Resistance Surveillance Workgroup. Singapore: NARSW Report, Jan-Mar 2006.
60. Schneiders T, Amyes SG, Levy SB. Role of AcrR and ramA in fluoroquinolone resistance in clinical Klebsiella pneumoniae isolates from Singapore. Antimicrob Agents Chemother 2003;47:2831-7.
61. Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis 2006;6:629-40.
62. Warren RE, Ensor VM, O'Neill P, Butler V, Taylor J, Nye K, et al. Imported chicken meat as a potential source of quinolone-resistant Escherichia coli producing extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother 2008;61:504-8.
63. European Antimicrobial Resistance Surveillance System. Available at: http://www.rivm.nl/earss/database. Accessed 2 February 2008.