Adenosine A1 receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia

Acta Physiologica Scandinavica

Volumn 182, Issue 2, 2004, Pages 133-143

  Schulte, G ^a   Sommerschild, H ^a   Yang, J ^a   Tokuno, S ^a,c   Goiny, M ^a   Lovdahl C ^a   Johansson, B ^a   Fredholm, B B ^a   Valen, G ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF OSLO   (Norway)

^c Medical Services   (Japan)

Author keywords

Adenosine A1 receptors; Cardioprotection; Ischaemia reperfusion; Mitogen activated protein kinases; Pre conditioning

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A3 RECEPTOR; HYPOXANTHINE; INOSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; XANTHINE; MITOGEN ACTIVATED PROTEIN KINASE 3;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOBLOTTING; ISOLATED HEART; KNOCKOUT MOUSE; MICRODIALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; ANIMAL; GENE DELETION; GENETICS; HEART; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE REPERFUSION; MALE; METABOLISM; METHODOLOGY; MOUSE MUTANT; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE; ANIMALS; BRAIN ISCHEMIA; GENE DELETION; HEART; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, KNOCKOUT; MICRODIALYSIS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTOR, ADENOSINE A1; VENTRICULAR FUNCTION, LEFT;

EID: 5644294401     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-201X.2004.01350.x     Document Type: Article

References (34)

1. Baxter, G.F. 2002. Role of adenosine in delayed preconditioning of myocardium. Cardiovasc Res 55, 483-494.
2. Bell, R.M., Smith, C.C. & Yellon, D.M. 2002. Nitric oxide as a mediator of delayed pharmacological (A(1) receptor triggered) preconditioning; is eNOS masquerading as iNOS? Cardiovasc Res 53, 405-413.
3. Bolli, R. 2001. Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol 33, 1897-1918.
4. ATP Channel. Annu Rev Physiol 62, 79-109.
5. Dickson, E.W., Lorbar, M., Porcaro, W.A. et al. 1999. Rabbit heart can be 'preconditioned' via transfer of coronary effluent. Am J Physiol 277, 2451-2457.
6. Doevendans, P.A., Daemen, M.J., Muinck, E.D. & de Smits, J.F. 1998. Cardiovascular phenotyping in mice. Cardiovasc Res 39, 34-49.
7. Fredholm, B.B., Ijzerman, A.P., Jacobson, K.A., Klotz, K.-N. & Linden, J. 2001. International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53, 527-552.
8. Fuji, M., Hara, H., Meng, W., Vonsattel, J.P., Huang, Z. & Moskowitz, M.A. 1997. Strain-related differences in suspeptibility to transient forebrain ischemia in SV-129 and C57black/6 mice. Stroke 28, 1805-1810.
9. Gho, B.C., Schoemaker, R.G., van den Doel, M.A., Duncker, D.J. & Verdouw, P.D. 1996. Myocardial protection by brief ischemia in noncardiac tissue. Circulation 94, 2193-2200.
10. Grabb, M.C., Sciotti, V.M., Gidday, J.M., Cohen, S.A. & Van Wylen, D.G.L. 1998. Neurochemical and morphological responses to acutely and chronically implanted brain microdialysis probes. J Neurosci Methods 82, 25-34.
11. 3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning. J Mol Cell Cardiol 33, 825-830.
12. Haq, S.E.A., Clerk, A. & Sugden, P.H. 1998. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart. FEBS Lett 434, 305-308.
13. 1 receptor. Proc N Y Acad Sci 98, 9407-9412.
14. Kondoh, S., Nagasawa, S., Kawanishi, M., Yamaguchi, K., Kajimoto, S. & Ohta, T. 1999. Effects of ebselen on cerebral ischemia and reperfusion evaluated by microdialysis. Neurol Res 21, 682-686.
15. Kuzuya, T., Hoshida, S., Yamashita, N. et al. 1993. Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia. Circ Res 72, 1293-1299.
16. Li, G., Tokuno, S., Thäepold, P., Vaage, J., Löwbeer, C. & Valen, G. 2001. Preconditioning protects the severely atherosclerotic mouse heart. Ann Thorac Surg 71, 1296-1304.
17. Marais, E., Genade, S., Strijdom, H., Moolman, J.A. & Lochner, A. 2001. p38 MAPK activation triggers pharmacologically-induced β-adrenergic preconditioning, but not ischaemic preconditioning. J Mol Cell Cardiol 33, 2157-2177.
18. Marber, M.S., Latchman, D.S., Walker, J.M. & Yellon, D.M. 1993. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation 88, 1264-1272.
19. Murry, C.E., Jennings, R.B. & Reimer, K.A. 1986. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74, 1124-1136.
20. Nayeem, M.A., Matherne, G.P. & Mustafa, S.J. 2003. Ischemic and pharamcological preconditioning induces further delayed protection in transgenic mouse cardiomyocytes overexpressing adenosine A(1) (A(1)AR) receptors: Role of A (1) AR, iNOS, and K (ATP) channels. Naunyn Schmiedebergs Arch Pharamcol 367, 219-226.
21. Nyce, J.W. 1999. Insight into adenosine receptor function using antisense and gene-knockout approaches. TIPS 20, 79-83.
22. Pell, T.A., Baxter, G.F., Yellon, D.M. & Drew, G.M. 1998. Renal ischemia preconditions myocardium; role of adenosine receptors and ATP-sensitive potassium channels. Am J Physiol 275, H1524-H1547.
23. 1MF-2 cells. Eur J Pharmacol 413, 151-161.
24. 3 receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. Mol Pharm 58, 477-482.
25. Schulte, G. & Fredholm, B.B. 2003. Signaling from adenosine receptors to mitigen activated protein kinases. Cell Signal 15, 813-827.
26. Sommerschild, H.T. & Kirkeböen, K.A. 2000. Adenosine and cardioprotection during ischemia and reperfusion - an overview. Acta Anaesthesiol Scand 44, 1038-1055.
27. 3 adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms. Circ Res 88, 520-528.
28. Takaoka, A., Nakae, I., Mitsunami, K. et al. 1999. Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of 'remote preconditioning'. J Am Coll Cardiol 33, 556-564.
29. Tekin, D., Xi, L., Zhao, T., Tejero-Taldo, M.I., Atluri, S. & Kukreja, R.C. 2001. Mitogen-activated protein kinases mediate heat shock-induced delayed protection in mouse heart. Am J Physiol 281, H523-H532.
30. Tokuno, S., Hinokiyama, K., Tokuno, K., Löwbeer, C. & Valen, G. 2002. Spontaneous ischemic events in the heart and brain preconditions the hearts of severely atherosclerotic mice. Atherosclerosis, Thrombosis and Vascular Biology 22, 995-1001.
31. Yellon, D.M., Baxter, G.F., Garcia-Dorado, D., Heusch, G. & Sumeray, M.S. 1998. Ischemic preconditioning: present positions and future directions. Cardiovasc Res 37, 21-33.
32. Yu, A.C. & Lau, L.T. 2000. Expression of interleukin-1 alpha, tumor necrosis factor α and interleukin-6 genes in astrocytes under ischemic injury. Neurochem Int 36, 369-377.
33. Zhao, T.C. & Kukreja, R.C. 2002. Late preconditioning elicited by activation of adenosine A (3) receptor in heart: role of NF-kappa B, iNOS and mitochondrial K(ATP) channel. J Mol Cell Cardiol 34, 263-277.
34. 1 receptors. Evidence from gene-knockout mice. Circulation 102, 902-907.