Laminar distribution of GABA A- and glycine-receptor mediated tonic inhibition in the dorsal horn of the rat lumbar spinal cord: Effects of picrotoxin and strychnine on expression of Fos-like immunoreactivity

Pain

Volumn 112, Issue 1-2, 2004, Pages 156-163

  Cronin, John N ^a   Bradbury, Elizabeth J ^a   Lidierth, Malcolm ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Allodynia; GABA; Glycine; Hyperalgesia; Neuropathic pain; Tonic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; GLYCINE RECEPTOR; GLYCINE RECEPTOR ANTAGONIST; PICROTOXIN; PROTEIN FOS; STRYCHNINE; PROTEIN C FOS;

ALLODYNIA; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HYPERSENSITIVITY; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; ANIMAL; BIOSYNTHESIS; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; IMMUNOCHEMISTRY; LUMBAR VERTEBRA; METABOLISM; NERVE CELL INHIBITION; PHYSIOLOGY; POSTERIOR HORN CELL; SPRAGUE DAWLEY RAT;

ANIMALS; GENE EXPRESSION REGULATION; IMMUNOCHEMISTRY; LUMBAR VERTEBRAE; MALE; NEURAL INHIBITION; PICROTOXIN; POSTERIOR HORN CELLS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECEPTORS, GLYCINE; STRYCHNINE;

EID: 5644284554     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2004.08.010     Document Type: Article

References (50)

1. S. Ahmadi, U. Muth-Selbach, A. Lauterbach, P. Lipfert, W.L. Neuhuber, and H.U. Zeilhofer Facilitation of spinal NMDA receptor currents by spillover of synaptically released glycine Science 300 2003 2094 2097
2. M. Antal, M. Petko, E. Polgar, C.W. Heizmann, and J. Storm-Mathisen Direct evidence of an extensive GABAergic innervation of the spinal dorsal horn by fibres descending from the rostral ventromedial medulla Neuroscience 73 1996 509 518
3. T. Araki, M. Yamano, T. Murakami, A. Wanaka, H. Betz, and M. Tohyama Localization of glycine receptors in the rat central nervous-system - an immunocytochemical analysis using monoclonal-antibody Neuroscience 25 1988 613 624
4. A.I. Basbaum Distribution of glycine receptor immunoreactivity in the spinal cord of the rat: cytochemical evidence for a differential glycinergic control of lamina I and V nociceptive neurons J Comp Neurol 278 1988 330 336
5. C. Beyer, L.A. Roberts, and B.R. Komisaruk Hyperalgesia induced by altered glycinergic activity at the spinal cord Life Sci 37 1985 875 882
6. J.M. Castro-Lopes, M. Malcangio, B.H. Pan, and N.G. Bowery Complex changes of GABAA and GABAB receptor binding in the spinal cord dorsal horn following peripheral inflammation or neurectomy Brain Res 679 1995 289 297
7. N. Chery, and Y. De Koninck Junctional versus extrajunctional glycine and GABA(A) receptor-mediated IPSCs in identified lamina I neurons of the adult rat spinal cord J Neurosci 19 1999 7342 7355
8. N. Chery, and Y. De Koninck GABA(B) receptors are the first target of released GABA at lamina I inhibitory synapses in the adult rat spinal cord J Neurophysiol 84 2000 1006 1011
9. R.E. Coggeshall, and W.D. Willis Sensory mechanisms of the spinal cord 1991 Plenum New York
10. J.A.M. Coull, D. Boudreau, K. Bachand, S.A. Prescott, F. Nault, A. Sik, P. De Koninck, and Y. De Koninck Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain Nature 424 2003 938 942
11. D.R. Curtis, A.W. Duggan, and G.A.R. Johnston Glycine, strychnine, picrotoxin and spinal inhibition Brain Res 14 1969 759 762
12. D. Denny-Brown, E.J. Kirk, and N. Yanagisawa The tract of Lissauer in relation to sensory transmission in the dorsal horn of spinal cord in the macaque monkey J Comp Neurol 151 1973 175 200
13. T. Doubell, R.J. Mannion, and C.J. Woolf The dorsal horn: state-dependent sensory processing, plasticity and the generation of pain P.D. Wall R. Melzack Textbook of pain 1999 Churchill-Livingstone Edinburgh 165 181
14. G.M. Drew, P.J. Siddall, and A.W. Duggan Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn Pain 109 2004 379 388
15. J.X. Hao, X.J. Xu, H. Aldskogius, A. Seiger, and Z. Wiesenfeld-Hallin Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation Pain 45 1991 175 185
16. D.G. Herrera, and H.A. Robertson Activation of c-fos in the brain Prog Neurobiol 50 1996 83 107
17. S.P. Hunt, A. Pini, and G. Evan Induction of c-fos-like protein in spinal cord neurons following sensory stimulation Nature 328 1987 632 634
18. S.J. Hwang, S. Pagliardini, A. Rustioni, and J.G. Valtschanoff Presynaptic kainate receptors in primary afferents to the superficial laminae of the rat spinal cord J Comp Neurol 436 2001 275 289
19. G.A.R. Johnston GABA(A) receptor pharmacology Pharmacol Ther 69 1996 173 198
20. V.K. Kontinen, and T.F. Meert Vocalization responses after spinal administration of bicuculline or strychnine in rats Neuromodulation 5 2002 221 230
21. V.K. Kontinen, L.C. Stanfa, A. Basu, and A.H. Dickenson Electrophysiologic evidence for increased endogenous GABAergic but not glycinergic inhibitory tone in the rat spinal nerve ligation model of neuropathy Anesthesiology 94 2001 333 339
22. I. Lever, J. Cunningham, J. Grist, P.K. Yip, and M. Malcangio Release of BDNF and GABA in the dorsal horn of neuropathic rats Eur J Neurosci 18 2003 1169 1174
23. M. Lidierth, and P.D. Wall Dorsal horn cells connected to the Lissauer tract and their relation to the dorsal root potential in the rat J Neurophysiol 80 1998 667 679
24. T.P. Malan, H.P. Mata, and F. Porreca Spinal GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain Anesthesiology 96 2002 1161 1167
25. D.L. McNeill, R.E. Coggeshall, and S.M. Carlton A light and electron microscopic study of calcitonin gene-related peptide in the spinal cord of the rat Exp Neurol 99 1988 699 708
26. M.J. Millan The induction of pain: an integrative review Prog Neurobiol 57 1999 1 164
27. M.J. Millan Descending control of pain Prog Neurobiol 66 2002 355 474
28. K. Mitchell, R.C. Spike, and A.J. Todd An immunocytochemical study of glycine receptor and GABA in laminae I-III of rat spinal dorsal horn J Neurosci 13 1993 2371 2381
29. C. Molander, Q. Xu, and G. Grant The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord J Comp Neurol 230 1984 133 141
30. K.A. Moore, T. Kohno, L.A. Karchewski, J. Scholz, H. Baba, and C.J. Woolf Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord J Neurosci 22 2002 6724 6731
31. S. Rajendra, J.W. Lynch, and P.R. Schofield The glycine receptor Pharmacol Ther 73 1997 121 146
32. A.J. Reeve, A.H. Dickenson, and N.C. Kerr Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist J Neurophysiol 79 1998 1494 1507
33. L.A. Roberts, C. Beyer, and B.R. Komisaruk Nociceptive responses to altered GABAergic activity at the spinal cord Life Sci 39 1986 1667 1674
34. A. Semyanov, M.C. Walker, and D.M. Kullmann GABA uptake regulates cortical excitability via cell type-specific tonic inhibition Nat Neurosci 6 2003 484 490
35. A. Semyanov, M.C. Walker, D.M. Kullmann, and R.A. Silver Tonically active GABA(A) receptors: modulating gain and maintaining the tone Trends Neurosci 27 2004 262 269
36. S.E. Sherman, and C.W. Loomis Strychnine-sensitive modulation is selective for non-noxious somatosensory input in the spinal cord of the rat Pain 66 1996 321 330
37. S.E. Sherman, L. Luo, and J.O. Dostrovsky Altered receptive fields and sensory modalities of rat VPL thalamic neurons during spinal strychnine-induced allodynia J Neurophysiol 78 1997 2296 2308
38. S.E. Sherman, L. Luo, and J.O. Dostrovsky Spinal strychnine alters response properties of nociceptive-specific neurons in rat medial thalamus J Neurophysiol 78 1997 628 637
39. P.J. Siddall, C.L. Xu, N. Floyd, and K.A. Keay C-fos expression in the spinal cord of rats exhibiting allodynia following contusive spinal cord injury Brain Res 851 1999 281 286
40. L. Sivilotti, and C.J. Woolf The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord J Neurophysiol 72 1994 169 179
41. L.S. Sorkin, and S. Puig Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist Pain 68 1996 283 292
42. L.S. Sorkin, S. Puig, and D.L. Jones Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists Pain 77 1998 181 190
43. A.J. Todd, and A.C. Sullivan Light-microscope study of the coexistence of gaba-like and glycine-like immunoreactivities in the spinal-cord of the rat J Comp Neurol 296 1990 496 505
44. A.J. Todd, R.C. Spike, A.R. Brodbelt, R.F. Price, and S.A. Shehab Some inhibitory neurons in the spinal cord develop c-fos-immunoreactivity after noxious stimulation Neuroscience 63 1994 805 816
45. A.N. van den Pol, and T. Gorcs Glycine and glycine receptor immunoreactivity in brain and spinal cord J Neurosci 8 1988 472 492
46. P.D. Wall, and M. Devor The effect of peripheral nerve injury on dorsal root potentials and on transmission of afferent signals into the spinal cord Brain Res 209 1981 95 111
47. P.D. Wall, and M. Lidierth Five sources of a dorsal root potential: their interactions and origins in the superficial dorsal horn J Neurophysiol 78 1997 860 871
48. P.D. Wall, M. Lidierth, and P. Hillman Brief and prolonged effects of Lissauer tract stimulation on dorsal horn cells Pain 83 1999 579 589
49. T.L. Yaksh Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists Pain 37 1989 111 123
50. R.P. Yezierski Pain following spinal cord injury: the clinical problem and experimental studies Pain 68 1996 185 194