Biomarkers of human skin cells identified using DermArray DNA arrays and new bioinformatics methods

Biochemical and Biophysical Research Communications

Volumn 291, Issue 4, 2002, Pages 1052-1064

  Curto, Ernest V ^a   Lambert, Glenna W ^a   Davis, Richard L ^a   Wilborn, Teresa W ^a   Dooley, Thomas P ^a  

^a IntegriDerm Inc   (United States)

Author keywords

Algorithm; Differentiation; DNA array; DNA microarray; Fibroblast; Keratinocyte; Melanocyte

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; RNA;

ALGORITHM; ANALYTIC METHOD; ARTICLE; BIOINFORMATICS; CELL TYPE; CONTROLLED STUDY; DNA MICROARRAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; KERATINOCYTE; MATHEMATICAL ANALYSIS; MELANOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CELL; SKIN FIBROBLAST;

EID: 0036296666     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6542     Document Type: Article

References (47)

1. Improved barrier structure formation in air-exposed human keratinocyte culture systems
2. Beauty is skin deep: The fascinating biology of the epidermis and its appendages
3. Human pigmentation genetics: The difference is only skin deep
4. Similar, but not identical, modulation of expression of extracellular matrix components during in vitro and in vivo aging of human skin fibroblasts
5. High-density cDNA filter analysis: A novel approach for large-scale, quantitative analysis of gene expression
6. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
7. Comparison of normal human skin gene expression using cDNA microarrays
8. Thermodynamics, molecules and the Gibbs conference
9. TGF beta promotes the basal phenotype of epidermal keratinocytes: Transcriptional induction of K#5 and K#14 keratin genes
10. A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering
11. Keratin 14 gene mutations in patients with epidermolysis bullosa simplex
12. Cell density and culture factors regulate keratinocyte commitment to differentiation and expression of suprabasal K1/K10 keratins
13. The wound repair-associated keratins 6, 16, and 17. Insights into the role of intermediate filaments in specifying keratinocyte cytoarchitecture
14. A mutation in the mucosal keratin K4 is associated with oral white sponge nevus
15. Functional differences between keratins of stratified and simple epithelia
16. Temporal and spatial sequence expression of cytokeratin K19 in cultured human keratinocyte
17. Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage
18. Human keratinocytes adhere to a unique heparin-binding peptide sequence within the triple helical region of type IV collagen
19. Genetic analysis of the epidermal differentiation complex (EDC) on human chromosome 1q21: Chromosomal orientation, new markers, and a 6-Mb YAC contig
20. Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21
21. Annexins I and II show differences in subcellular localization and differentiation-related changes in human epidermal keratinocytes
22. S100A2, a putative tumor suppressor gene, regulates in vitro squamous cell carcinoma migration
23. Immunohistochemical localization of the Ca2+ binding S100 proteins in normal human skin and melanocytic lesions
24. Prognostic significance of the Ca(2+) binding protein S100A2 in laryngeal squamous-cell carcinoma
25. The Ca2+-binding proteins S100A8 and S100A9 are encoded by novel injury-regulated genes
26. S100A7, S100A10, and S100A11 are transglutaminase substrates
27. Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function
28. Homeobox genes and skin development: A review
29. HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development
30. Coordinate regulation of HOX genes in human hematopoietic cells
31. Chromosomal mapping of human keratin genes: Evidence of non-linkage
32. Cooperative interactions between PBX, PREP, and HOX proteins modulate the activity of the alpha 2(V) collagen (COL5A2) promoter
33. Skin aging and photoaging: The role of DNA damage and repair
34. Cellular and molecular mechanisms of cutaneous aging
35. Transmembrane crosstalk between the extracellular matrix and the cytoskeleton
36. Multiexon deletions in the type I collagen COL1A2 gene in osteogenesis imperfecta type IB. Molecules containing the shortened alpha2(I) chains show differential incorporation into the bone and skin extracellular matrix
37. Inherited disorders of collagen gene structure and expression
38. Reduced collagen VI causes Bethlem myopathy: A heterozygous COL6A1 nonsense mutation results in mRNA decay and functional haplo insufficiency
39. Coding sequence and growth regulation of the human vimentin gene
40. Rigidity of circulating lymphocytes is primarily conferred by vimentin intermediate filaments
41. Homologous pigmentation mutations in human, mouse and other model organisms
42. Analysis of mammalian pigmentation at the molecular level
43. Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides
44. MHC class I molecules, structure and function
45. An immunocytochemical study of MHC class I expression on human Langerhans cells and melanocytes
46. Bootstrapping cluster analysis: Assessing the reliability of conclusions from microarray experiments