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ERN amplitude increases when subjects favor accuracy over speed, whereas ERN amplitude is reduced as error rates increase (13, 16). If we would accept higher error rates after alcohol, then ERN amplitude might vary with alcohol dosage because of the effects of alcohol not on error detection (expressed in ERN amplitude) but on error rate (which in turn covaries with ERN amplitude). Should our procedure incur a speed-accuracy tradeoff to obtain comparable error percentages across alcohol conditions, then the relative emphasis on accuracy after alcohol should result in larger ERNs, which would oppose the alcohol-induced reduction in ERN amplitude anticipated here, thus rendering our ap proach a conservative one.
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The research of K.R.R. and G.P.H.B. was supported by the Royal Netherlands Academy of Arts and Sciences. Helpful comments by S. Nieuwenhuis and technical assistance by W. van den .Wildenberg Wildenberg are gratefully acknowledged.
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