Looking through ion channels: Recharged concepts in T-cell signaling

Trends in Immunology

Volumn 25, Issue 11, 2004, Pages 565-569

  Panyi, György ^a   Vámosi, György ^a   Bodnár, Andrea ^a   Gáspár, Rezso ^a   Damjanovich, Sándor ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; DILTIAZEM; ION CHANNEL; POTASSIUM CHANNEL; VERAPAMIL; VOLTAGE GATED POTASSIUM CHANNEL;

CALCIUM TRANSPORT; CELL ACTIVATION; HUMAN; IMMUNOREACTIVITY; MULTIPLE SCLEROSIS; NONHUMAN; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE; T LYMPHOCYTE;

EID: 5644228811     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2004.09.002     Document Type: Short Survey

References (28)

1. D.R. Matteson, and C. Deutsch K channels in T lymphocytes: a patch clamp study using monoclonal antibody adhesion Nature 307 1984 468 471
2. + channels in human T lymphocytes: a role in mitogenesis? Nature 307 1984 465 468
3. G. Panyi Ion channels and lymphocyte activation Immunol. Lett. 92 2004 55 66
4. M.D. Cahalan Molecular properties and physiological roles of ion channels in the immune system J. Clin. Immunol. 21 2001 235 252
5. R.S. Lewis Calcium signaling mechanisms in T lymphocytes Annu. Rev. Immunol. 19 2001 497 521
6. + channels as targets for specific immunomodulation Trends Pharmacol. Sci. 25 2004 280 289
7. J. Cui CaT1 contributes to the stores-operated calcium current in Jurkat T-lymphocytes J. Biol. Chem. 277 2002 47175 47183
8. 2+ channels in human T cells: pharmacology and molecular characterization of the major α pore-forming and auxiliary β-subunits J. Biol. Chem. 279 2004 19566 19573
9. 2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2 J. Biol. Chem. 279 2004 12427 12437
10. + channel in effector memory T cells as new target for MS J. Clin. Invest. 111 2003 1703 1713
11. G. Panyi Colocalization and nonrandom distribution of Kv1.3 potassium channels and CD3 molecules in the plasma membrane of human T lymphocytes Proc. Natl. Acad. Sci. U. S. A. 100 2003 2592 2597
12. G. Panyi Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cells Proc. Natl. Acad. Sci. U. S. A. 101 2004 1285 1290
13. C.M. Fanger Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1 J. Biol. Chem. 274 1999 5746 5754
14. C.M. Fanger Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels J. Biol. Chem. 276 2001 12249 12256
15. 2+-inhibited cation (MIC) channels J. Gen. Physiol. 119 2002 487 507
16. M. Péter Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24 J. Membr. Biol. 179 2001 13 25
17. K. Kalman ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide J. Biol. Chem. 273 1998 32697 32707
18. V. Viglietta GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes J. Clin. Invest. 109 2002 895 903
19. P. Valverde Selective blockade of voltage-gated potassium channels reduces inflammatory bone resorption in experimental periodontal disease J. Bone Miner. Res. 19 2004 155 164
20. + effector memory cells relative to central memory cells Blood 103 2004 3986 3988
21. + channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis Proc. Natl. Acad. Sci. U. S. A. 98 2001 13942 13947
22. + channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation J. Immunol. 166 2001 936 944
23. P.A. van der Merwe Formation and function of the immunological synapse Curr. Opin. Immunol. 14 2002 293 298
24. + channels and T-cell synapses: the molecular background for efficient immunomodulation is shaping up Trends Pharmacol. Sci. 24 2003 385 389
25. G. Vereb Dynamic, yet structured: The cell membrane three decades after the Singer-Nicolson model Proc. Natl. Acad. Sci. U. S. A. 100 2003 8053 8058
26. + and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins J. Exp. Med. 191 2000 1167 1176
27. J. Bock Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms Biochem. Biophys. Res. Commun. 305 2003 890 897
28. R.E. Dolmetsch Calcium oscillations increase the efficiency and specificity of gene expression Nature 392 1998 933 936