Nanoscaffold matrices for size-controlled, pulsatile transdermal testosterone delivery: Nanosize effects on the time dimension

Nanotechnology

Volumn 19, Issue 43, 2008, Pages

  Malik, Ritu ^a   Tondwal, Shailesh ^b   Venkatesh, K S ^b   Misra, Amit ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ABS RESINS; CRYSTALLINE MATERIALS; CRYSTALLOGRAPHY; DISSOLUTION; DRUG DELIVERY; MICROSCOPIC EXAMINATION; NANOPARTICLES; NANOSTRUCTURES; POLYMER FILMS; POLYMERS; SKIN;

ADHERENT FILMS; CONTROLLED POROSITIES; DIFFUSION BEHAVIORS; DRUG RELEASES; INTERFERENCE PATTERNS; MOLECULAR STATES; NANO-SIZE EFFECTS; POLYMERIC FILMS; SIZE AND SHAPES; SKIN PERMEATIONS; TESTOSTERONE; TIME DIMENSIONS; TRANSDERMAL; VINYLIC POLYMERS;

CONTROLLED DRUG DELIVERY;

MOLECULAR SCAFFOLD; NANOPARTICLE; POLYVINYL ACETATE; POLYVINYL ALCOHOL; POVIDONE; TESTOSTERONE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; NONHUMAN; POROSITY; PRIORITY JOURNAL; PULSATILE HORMONE RELEASE; RAT; SCANNING ELECTRON MICROSCOPY; SKIN PERMEABILITY;

EID: 56349167639     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/19/43/435101     Document Type: Article

References (24)

1. O'Donnell L, Meacham S J, Stanton P G and McLachlan R I 2005 Knobil and Neill's Physiology of Reproduction ed J D Niell (St Louis, MO: Academic) pp 1017-70
2. Christiansen K 2004 Testosterone: Action, Deficiency, Substitution ed S Nieschlag et al (Cambridge: Cambridge University Press) pp 125-72
3. Yan H H, Mruk D D, Lee W M and Cheng C Y 2008 Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells FASEB J. 22 1945-59
4. Maddocks S, Hargreave T B, Reddie K, Fraser H M, Kerr J B and Sharpe R M 1993 Intratesticular hormone levels and the route of secretion of hormones from the testis of the rat, guinea pig, monkey and human Int. J. Androl. 16 272-8
5. Bablok L, Janczewski Z and Czaplicki M 1984 Testosterone, FSH and LH in human spermatic and cubital venous plasma in post-inflammatory azoospermia Andrologia 16 525-7
6. Bablok L, Janczewski Z and Czaplicki M 1985 Testosterone, FSH and LH in human spermatic and cubital venous plasma in varicocele patients Andrologia 17 346-51
7. Foresta C, Bordon P, Rossato M, Mioni R and Veldhuis J D 1997 Specific linkages among luteinizing hormone, follicle-stimulating hormone, and testosterone release in the peripheral blood and human spermatic vein: evidence for both positive (feed-forward) and negative (feedback) within-axis regulation J. Clin. Endocrinol. Metab. 82 3040-6
8. Morelli A, Corona G, Filippi S, Ambrosini S, Forti G, Vignozzi L and Maggi M 2007 Which patients with sexual dysfunction are suitable for testosterone replacement therapy? J. Endocrinol. Invest. 30 880-8
9. Amory J K 2007 Contraceptive developments for men Drugs Today (BARC) 43 179-92
10. Grimes D A, Lopez L M, Gallo M F, Halpern V, Nanda K and Schulz K F 2007 Steroid hormones for contraception in men Cochrane. Database Syst. Rev. 18 CD004316
11. Liu P Y, Swerdloff R S, Christenson P D, Handelsman D J and Wang C 2006 Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis Lancet 367 1412-20
12. Misra A, Pal R, Majumdar S S, Talwar G P and Singh O 1997 Biphasic testosterone delivery profile observed with two different transdermal formulations Pharm. Res. 14 1264-8
13. Zitzmann M and Nieschlag E 2000 Hormone substitution in male hypogonadism Mol. Cell. Endocrinol. 161 73-88
14. Beiner M, Rengarajan G T, Pankaj S, Enke D and Steinhart M 2007 Manipulating the crystalline state of pharmaceuticals by nanoconfinement Nano Lett. 7 1381-5
15. Raghavan S L, Trividic A, Davis A F and Hadgraft J 2001 Crystallization of hydrocortisone acetate: influence of polymers Int. J. Pharm. 212 213-21
16. Misra A, Singh O and Talwar G P 1993 Film-forming lotion achieves controlled transdermal delivery Proc. Int. Symp. Control. Rel. Bioact. Mater. 20 414-5
17. Misra A, Raghuvanshi R, Ganga S, Diwan M, Talwar G and Singh O 1996 Formulation of a transdermal system for biphasic delivery of testosterone. J. Control. Release 39 1-7
18. Loi V, Vertzoni M, Vryonidou A and Phenekos C 2006 Development and validation of a simple reversed-phase high-performance liquid chromatography method for the determination of testosterone in serum of males J. Pharm. Biomed. Anal. 41 527-32
19. Harris R K, Joyce S A, Pickard C J, Cadars S and Emsley L 2006 Assigning carbon-13 NMR spectra to crystal structures by the INADEQUATE pulse sequence and first principles computation: a case study of two forms of testosterone Phys. Chem. Chem. Phys. 8 137-43
20. Roberts P J, Pettersen R C, Sheldrick G M, Isaacs N W and Kennard O 1973 Crystal and molecular structure of 17beta-hydroxyandrost-4-en-3-one (testosterone) J. Chem. Soc., Perkin Trans. 2 1973-84
21. Smolensky M H and Peppas N A 2007 Chronobiology, drug delivery, and chronotherapeutics Adv. Drug Deliv. Rev. 59 828-51
22. Huynh D P, Nguyen M K, Pi B S, Kim M S, Chae S Y, Lee K C, Kim B S, Kim S W and Lee D S 2008 Functionalized injectable hydrogels for controlled insulin delivery Biomaterials 29 2527-34
23. Mohamad A and Dashevsky A 2006 pH-independent pulsatile drug delivery system based on hard gelatin capsules and coated with aqueous dispersion Aquacoat ECD Eur. J. Pharm. Biopharm. 64 173-9
24. Mohamad A and Dashevsky A 2007 In vitro and in vivo performance of a multiparticulate pulsatile drug delivery system Drug Dev. Ind. Pharm. 33 113-9