DNA repair and chromosomal alterations

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 657, Issue 1, 2008, Pages 3-7

  Natarajan, Adayapalam T ^a   Palitti, Fabrizio ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Acetaldehyde; BPDE; Chromosomal aberrations; DNA double strand breaks; DNA repair; Ionising radiation

Indexed keywords

ALCOHOL;

ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL MUTANT; CHO CELL; CHROMATID ABERRATION; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; DNA DAMAGE; DNA REPAIR; EXPERIMENTAL ANIMAL; GENE FREQUENCY; HAMSTER; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL;

ACETALDEHYDE; ANIMALS; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; MUTAGENS; RADIATION, IONIZING; RECOMBINATION, GENETIC; SISTER CHROMATID EXCHANGE;

CRICETULUS GRISEUS;

EID: 56349162470     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.08.017     Document Type: Article

References (30)

1. Natarajan A.T. Chromosome aberrations: past, present and future. Mutat. Res. 594 (2002) 3-16
2. Sax K. An analysis of X-ray induced chromosome aberrations in Tradescantia. Genetics 25 (1940) 41-68
3. Serebovsky A.S. A general scheme for origin of mutations. Am. Nat. 63 (1929) 374-378
4. Revell S.H. The accurate estimation of chromatid breakage and its relevance to a new interpretation of chromatid aberrations by ionizing radiations. Proc. R. Soc. Lond. Ser. B 159 (1959) 563-589
5. Evans H.J., and Savage J.R.K. The relation between DNA synthesis and chromosome structure as revealed by X-ray damage. J. Cell Biol. 18 (1963) 525-540
6. Evans H.J., and Scott D. The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis. Proc. R. Soc. Lond. B: Biol. Sci. 173 (1969) 419-512
7. Kihlman B.A. Caffeine and Chromosomes (1977), Elsevier, Amsterdam pp. 504
8. Bender M.A., Griggs H.G., and Bedford J.S. Mechanisms of chromosomal aberration production. III. Chemicals and ionizing radiation. Mutat. Res. 23 (1974) 137-149
9. Natarajan A.T., Obe G., van Zeeland A.A., Palitti F., Meijers M., and Verdegaal-Immerzell E.A.M. Molecular mechanisms involved in the production of chromosomal aberrations. II. Utilization of Neurospora endonuclease for the study of aberration production by X-rays in G1 and G2 stages of the cell cycle. Mutat. Res. 69 (1980) 293-305
10. Natarajan A.T., Berni A., Marimuthu K.M., and Palitti F. The type and yield of ionizing radiation induced chromosomal aberrations depend on the efficiency of different DSB repair pathways in mammalian cells. Mutat. Res. 642 (2008) 80-85
11. Meschini R., Marotta E., Berni A., Filippi S., Fiore M., Mancinelli P., Natarajan A.T., and Palitti F. DNA repair deficiency and BPDE-induced chromosomal alterations in CHO cells. Mutat. Res. 637 (2007) 93-100
12. Mechilli M., Schinoppi A., Kobos K., Natarajan A.T., and Palitti F. DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells. Mutagenesis 23 (2008) 51-56
13. Natarajan A.T., Darroudi F., Mullenders L.H., and Meijers M. The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations. Mutat. Res. 160 (1986) 231-236
14. Grigorova M., and Natarajan A.T. Relative involvement of chromosome 21in radiation induced exchange aberrations in lymphocytes of Down's syndrome patients. Mutat. Res. 404 (1998) 67-78
15. Marcon F., Boei J.J.W.A., and Natarajan A.T. Recombination between homologous chromosomes do not play a dominant role in the formation of radiation-induced chromosomal aberrations. Int. J. Radiat. Biol. 76 (2000) 1343-1348
16. Takata M., Sasaki M.S., Sonoda E., Morrison C., Hashomoto M., Utsumi H., Yamaguchi-Iwai Y., Shinohara A., and Takeda S. Homologous recombination and non-homologous end-joining pathways pf DNA double strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 17 (1998) 5497-5508
17. Taylor A.M.R. Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested by cytogenetic observations. Mutat. Res. 50 (1978) 407-418
18. Natarajan A.T., and Meyers M. Chromosomal radio-sensitivity of ataxia-telangiectasia cells at different cell cycle stages. Hum. Genet. 52 (1979) 127-132
19. Darroudi F., and Natarajan A.T. Cytological characterization of Chinese hamster ovary X-ray sensitive mutant cells xrs 5 and xrs 6. I. Induction of chromosomal aberrations by X-irradiation and its modulation with 3-aminobenzamide and caffeine. Mutat. Res. 177 (1987) 133-148
20. Tucker J.D., Jones N.J., Allen N.A., Minkler J.L., Thompson L.H., and Carrano A.V. Cytogenetic characterization of ionising radiation sensitive Chinese hamster mutant irs1. Mutat. Res. 254 (1991) 143-152
21. Rothkamm K., Kruger I., Thompson L.H., and Loebrich M. Pathways of DNA double strand breaks repair during the mammalian cell cycle. Mol. Cell Biol. 23 (2003) 5706-5715
22. Iliakis G., Wang H., Perrault J.A.R., Boecker W., Rosidi B., Windhofer F., Wu W., Guan J., Terzoudi G., and Pantelias G. Mechanisms of DNA double strand break repair and chromosome aberration formation. Cytogenet. Genome Res. 104 (2004) 14-20
23. Braithwite R., Wu X., and Wang Z. Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis 19 (1998) 1239-1246
24. Obe G., Natarajan A.T., Meyers M., and den Hertog A. Induction of chromosomal aberrations in peripheral lymphocytes of human blood in vitro and SCEs in bone-marrow cells in vivo by ethanol and its metabolite acetaldehyde. Mutat. Res. 68 (1979) 291-294
25. Rothfuss A., and Grompe M. Repair kinetics of genomic interstrand DNA double strand-break-dependent activation of Fanconi anemia/BRACA pathway. Mol. Cell Biol. 24 (2004) 123-134
26. van Kesteren-van Leeuwen A.C., and Natarajan A.T. Localisation of 7-12-dimethylbenz(a)anthracene induced chromatid breaks and sister chromatid exchanges in chromosomes 1 and 2 of bone marrow cells of rat in vivo. Chromosoma 81 (1980) 297-307
27. Sasaki M.S., Takata M., Sonoda E., Tachibana A., and Takeda S. Recombination repair pathway in the maintenance of chromosome integrity against DNA interstrand crosslinks. Cytogenet. Genome Res. 104 (2004) 28-34
28. Virsik-Kopp P., Hofman-Huther H., Rave-Frank M., and Schmidberger H. The effect of wortaminnin on radiation-induced chromosome aberration formation in the radioresistant tumor cell line WiDr. Radiat. Res. 164 (2005) 148-156
29. Gulston M., de Lara C., Jenner T., Davis E., and O'Neill P. Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 32 (2004) 1602-1609
30. Karlsson K.H., and Stenerlow B. Extensive ssDNA end formation at DNA double strand breaks in non-homologous end-joining deficient cells during S phase. BMC Mol. Biol. 8 (2007) 97