Neuroprotection by platelet-activating factor antagonism

Annals of the New York Academy of Sciences

Volumn 1053, Issue , 2005, Pages 455-456

  Tian, Xiaohua ^a   Bazan, Nicolas G ^a,b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Antagonist; BN 52021; Neuroprotection; Phospholipase; Phospholipid; Platelet activating factor (PAF)

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; GINKGOLIDE B; MEMBRANE PHOSPHOLIPID; PHOSPHOLIPASE A2; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ASTROCYTE; BRAIN HYPOXIA; BRAIN INJURY; CONFERENCE PAPER; ENDOTHELIUM CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; LONG TERM POTENTIATION; MEMORY; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROPROTECTION;

EID: 29744435061     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1344.057     Document Type: Conference Paper

References (11)

1. KATO, K., G.D. CLARK, N.G. BAZAN & C.F. ZORUMSKI. 1994. Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation. Nature 367: 175-179.
2. IZQUIERDO, I., C. FIN, P.K. SCHMITZ et al. 1995. Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc. Natl. Acad. Sci. USA 92: 5047-5051.
3. BAZAN, N.G., M.G. PACKARD, L. TEATHER & G. ALLAN. 1997. Bioactive lipids in excitatory neurotransmission and neuronal plasticity. Neurochem. Int. 30: 225-231.
4. HORROCKS, L.A. & A.A. FAROOQUI. 1994. NMDA receptor-stimulated release of arachidonic acid: mechanisms for the Bazan effect. In Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease, pp. 113-128. Plenum. New York.
5. SUN, G.Y., J. XU, M.D. JENSEN & A. SIMONYI. 2004. Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases. J. Lipid Res. 45: 205-213.
6. BAZAN, N.G., E.B. RODRIGUEZ DE TURCO & G. ALLAN. 1995. Mediators of injury in neurotrauma: intracellular signal transduction and gene expression. J. Neurotrauma 12: 791-814.
7. LIU, X.H., B.L. EUN, F.S. SILVERSTEIN & J.D. BARKS. 1996. The platelet-activating factor antagonist BN 52021 attenuates hypoxic-ischemic brain injury in the immature rat. Pediatr. Res. 40: 797-803.
8. OGDEN, F., M.A. DECOSTER & N.G. BAZAN. 1998. Recombinant plasma-type platelet-activating factor acetylhydrolase attenuates NMDA-induced hippocampal neuronal apoptosis. J. Neurosci. Res. 53: 677-684.
9. SQUINTO, S.P., A.L. BLOCK, P. BRAQUET & N.G. BAZAN. 1989. Platelet-activating factor stimulates a fos/jun/AP-1 transcriptional signaling system in human neuroblastoma cells. J. Neurosci. Res. 24: 558-566.
10. SQUINTO, S.P., P. BRAQUET, A.L. BLOCK & N.G. BAZAN. 1990. Platelet-activating factor activates HIV promoter in transfected SH-SY5Y neuroblastoma cells and MOLT-4 T lymphocytes. J. Mol. Neurosci. 2: 79-84.
11. BAZAN, N.G., S.P. SQUINTO, P. BRAQUET et al. 1991. Platelet-activating factor and polyunsaturated fatty acids in cerebral ischemia or convulsions: intracellular PAF-binding sites and activation of a fos/jun/AP-1 transcriptional signaling system. Lipids 26: 1236-1242.